Periodontitis

About the Disease
Periodontitis, also known as chronic pericementitis, is related to periodontitis, chronic and periodontitis, aggressive, 1, and has symptoms including leukorrhea and purulent discharge. An important gene associated with Periodontitis is CDKN2B-AS1 (CDKN2B Antisense RNA 1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Sodium fluoride and Menthol have been mentioned in the context of this disorder. Affiliated tissues include bone, neutrophil and endothelial, and related phenotypes are homeostasis/metabolism and immune system

Common Targets
NF-kappaB (NFkB) | CCR6 | IL1F10 | G7422 | IL37 | SFN | Matrix Metalloproteinase (MMP) (nonspecified subtype) | IL4R | TLR2 | CDKN2B-AS1 | Cyclophilins (nonspecified subtype) | NOD2 | G836 | Rho GTPase (nonspecified subtype) | SELL | MMP12 | PRDM1 | CTLA4 | MMP2 | CD14 | LRP5 | IRGM | CTSL | SIGLEC5 | Integrin Receptor (nonspecified subtype) | TGFBRAP1 | DDX39B | PDE5A | TNFSF13B | CAMTA1 | TLR9 | CHIT1 | GM-CSF Receptor (GM-CSF-R) | GSTP1 | CES1 | IFNG | G7099 | ATP6V1G2 | IL2 | G114548 | MCM3AP | G6772 | IL1A | MAPKAPK2 | ATP2A1 | ACKR1 | NEK7 | TGFB1 | G3576 | IL4 | ADGRE1 | MMP13 | IL1R1 | CHIA | FDPS | PTPN22 | MIR146A | QPCT | Cysteine Protease (nonspecified subtype) | LOC105378091 | C3 | TXNRD1 | LOC107984137 | NFKBIL1 | CTSC | MAOB | FCGR2A | ATP2A2 | NIN | FGFR2 | WTAPP1 | C5AR1 | IFIH1 | Vacuolar H+ ATPase | CTSK | MMP8 | PIN1 | IL16 | MMP1 | CTSB | G4780 | PTPN4 | IL18 | G7124 | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3 (PDE3) (nonspecified subtype) | CRP | MIR196A2 | ABCC4 | NFKB1 | NR3C1 | IL1RN | ANPEP | PDIA3 | LTA4H | G3569 | DEFB1 | G5743 | DNA-Directed DNA Polymerase Complex | G142 | IL12B | AQP6 | ACHE | MIR499A | G2099 | QPRT | TIMP3 | FCGR3B | LTF | IL1B | Integrin alphavbeta3 (vitronectin) receptor | VDR | IL2RA | KCNA3 | FCGR2B | G4318 | CYSLTR1 | CSF3 | HMGCR | MMP3 | Lipoxygenase (nonspecified subtype) | IL10 | PADI4 | COL1A1 | G4609 | LTA | UCP3

Note: If you'd like to get a target analysis report for Periodontitis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Periodontitis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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