Benign Familial Pemphigus

About the Disease
Benign Chronic Pemphigus, also known as hailey-hailey disease, is related to pemphigoid and pemphigus. An important gene associated with Benign Chronic Pemphigus is ATP2C1 (ATPase Secretory Pathway Ca2+ Transporting 1), and among its related pathways/superpathways are Nervous system development and Cardiac conduction. The drugs Acetylcholine and Cholinergic Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, testis and pituitary, and related phenotypes are hyperkeratosis and erythema

Common Targets
ATP2C1 | MC1R

Note: If you'd like to get a target analysis report for Benign Familial Pemphigus, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Benign Familial Pemphigus at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Glomerulonephritis | Niemann-Pick Disease, Type A | Spitz Nevus | Epidermal Nevus Syndrome | Senior-Loken Syndrome | Asthma, Nocturnal | Carcinoma, Merkel Cell | Neuropathy | Schwartz-Jampel-Aberfeld Syndrome | Echinococcosis | Aneurysm, Thoracic Aortic | Usher Syndrome Type IIC | Sengers Syndrome | Glutaric Aciduria Type 1 | Cerebellofaciodental Syndrome | Disseminated Superficial Actinic Porokeratosis | Glycogen Storage Disease Type 0 | Familial Glucocorticoid Deficiency | Proteus Syndrome | Gigantism | Glaucoma | LMNA-related Congenital Muscular Dystrophy | Ganglioglioma | Alopecia Areata | Amelogenesis Imperfecta | Chitayat Syndrome | Supravalvular Aortic Stenosis | Vitelliform Macular Dystrophy | Gestational Trophoblastic Disease | Spondyloepiphyseal Dysplasia Tarda, X-linked | Rett Syndrome | FG Syndrome | HIBCH Deficiency | Babesiosis | Keratosis, Actinic | Spinocerebellar Ataxia Type 6 | Renpenning Syndrome | Lichen Sclerosus | Mesothelioma, Malignant | Macrophage Activation Syndrome | Hypoplastic Left Heart Syndrome | Pierson Syndrome | Mannosidase Deficiency Diseases | Veno-occlusive Disease | Lattice Corneal Dystrophy | Chromosome 16p11.2 Deletion Syndrome | Albinism | Dengue Shock Syndrome | Behavioral Variant Of Frontotemporal Dementia | Herpes Genitalis | Sepiapterin Reductase Deficiency | Macrodactyly | Encephalitis, Tick-borne | Pemphigoid | Methemoglobinemia | Amebiasis | Actinomycetoma | Pyruvate Carboxylase Deficiency Disease | Endometriosis | Histoplasmosis | Hashimoto Thyroiditis | LEOPARD Syndrome | Combined Malonic And Methylmalonic Acidemia | Eosinophilia | Ovarian Hyperstimulation Syndrome | Peeling Skin Syndrome, Acral Type | Lupus Erythematosus | Maple Syrup Urine Disease | Leprosy | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Thrombophlebitis | Wolcott-Rallison Syndrome | Micropenis | Multicystic Renal Dysplasia | Toxoplasmosis | Meningococcal Infections | Cardiac Sarcoidosis | Eclampsia | Hyperphenylalaninemia | Pseudohypoparathyroidism Type 1C | Marinesco-Sjogren Syndrome | Dysequilibrium Syndrome | Angina Pectoris | Seizures-scoliosis-macrocephaly Syndrome | Hypospadias | Familial Digital Arthropathy-brachydactyly | Sitosterolemia | Menetrier Disease | Trichotillomania | Isobutyryl-CoA Dehydrogenase Deficiency | Craniofacial Dysostosis | Benign Recurrent Intrahepatic Cholestasis 1 | Neurodevelopmental Disorders | Tularemia | Myoclonus | Charcot-Marie-Tooth Disease Axonal Type 2N | Gastritis, Atrophic | Spermatocele | Hyperprolactinemia | Alpha-1 Antitrypsin Deficiency | Neuromyotonia | Androgen Insensitivity | Pfeiffer Syndrome | Usher Syndrome | Tetanus | Occipital Neuralgia | Esotropia | Myelofibrosis | Kohlschutter-Tonz Syndrome | Situs Inversus | Atelosteogenesis Type 1 | Multiple Sulfatase Deficiency | Juvenile Xanthogranuloma | Hemangioblastoma | Lymphoma | Lymphoma, Follicular | Synovitis | Retinal Vasculitis | Hyperinsulinism-hyperammonemia Syndrome | Hyperparathyroidism, Secondary | Mandibuloacral Dysplasia With Type A Lipodystrophy | Okihiro Syndrome | Primary Hyperoxaluria | Presbyopia | Cancer, Colon | Priapism | Autism | Menkes Disease | Familial Pheochromocytoma-paraganglioma | Vogt-Koyanagi-Harada Syndrome | Paraplegia | Botulism | GLUT1 Deficiency Syndrome | Dysplastic Nevus | Toxic Epidermal Necrolysis | Pituitary Stalk Interruption Syndrome | Cutis Laxa | Ichthyosis, X-linked | Christianson Syndrome | Rotor Syndrome | Infectious Diarrhea | Restless Legs Syndrome | Infantile Neuroaxonal Dystrophy | Atherosclerosis | Gastroschisis | Acanthosis Nigricans | Holt-Oram Syndrome | Acrodermatitis Enteropathica | Urea Cycle Disorder | Thymoma, Malignant | Esophageal Motility Disorders | Arthritis, Reactive | Familial Hypertrophic Cardiomyopathy | Aplasia Cutis Congenita | Malnutrition | Chronic Idiopathic Myelofibrosis | Malaria, Cerebral | Trimethylaminuria | Hypokalemia | Pterygium | Neurocysticercosis | Tetraplegia | Neurofibroma, Plexiform | Keloid | Blue Rubber Bleb Nevus Syndrome | Methylmalonic Aciduria And Homocystinuria, CblC Type | Osteomalacia | Chiari Malformation Type I | Azoospermia | Hyperandrogenemia | Renal-hepatic-pancreatic Dysplasia | C3 Glomerulonephritis | Cancer, Brain | Woodhouse-Sakati Syndrome | Aldosterone Synthase Deficiency | Corneal Neovascularization | Castleman Disease | Smith-Kingsmore Syndrome | Spinal Cord Diseases | Congenital Afibrinogenemia | Constipation | Pseudohypoaldosteronism | Persistent Mullerian Duct Syndrome | Multiple Sclerosis | Hypersomnia | Rhizomelic Chondrodysplasia Punctata | Primary Carnitine Deficiency | Spondylocostal Dysostosis | Paroxysmal Kinesigenic Dyskinesia | Malonyl-CoA Decarboxylase Deficiency | Pneumonia, Mycoplasma | Graft-versus-host Disease | Sarcoidosis, Pulmonary | Inflammatory Joint Disease | Nemaline Myopathy | Addison Disease | Retinal Telangiectasia | Thrombotic Microangiopathy | Osteosarcoma | Kabuki Syndrome 2 | Melanoma | Carotid Artery Disease | Hartnup Disease | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Chondrodysplasia Punctata | Calcium Pyrophosphate Deposition Disease | Pemphigus Foliaceus | Saul-Wilson Syndrome | Urolithiasis | Colitis, Microscopic | Bacterial Meningitis | Osteochondroma | Atelosteogenesis Type 2 | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Encephalopathy, Hepatic | Carpal Tunnel Syndrome | Riboflavin Transporter Deficiency Neuronopathy | Microvillus Inclusion Disease | Adult Polyglucosan Body Disease | Retinitis Pigmentosa 3 | Hepatitis D | Purpura | Immunoproliferative Disorders | Combined Pituitary Hormone Deficiency | Hyperglycemia | Fetal Akinesia Deformation Sequence | Spinocerebellar Ataxia Type 5 | Epidermolysis Bullosa Simplex | Malignant Peripheral Nerve Sheath Tumor | Bartsocas-Papas Syndrome | Creutzfeldt-Jakob Disease | Auriculocondylar Syndrome | Sulfite Oxidase Deficiency | Cleidocranial Dysplasia | Alpha-mannosidosis | Trachoma | Postaxial Polydactyly | Reticular Dysgenesis | Leukocyte Adhesion Deficiency | Hepatitis, Chronic | Dominant Optic Atrophy | Charcot-Marie-Tooth Disease Type 3 | Congenital Hypofibrinogenemia | Wolff-Parkinson-White Syndrome | Alazami Syndrome | Lipid Storage Myopathy | Vestibular Disease | VEXAS Syndrome | Esophagitis | Lung Diseases | Paronychia | Juvenile Polyposis | Primary Cutaneous Amyloidosis | Pontocerebellar Hypoplasia Type 2 | Hemochromatosis Type 2 | Primary Torsion Dystonia | Overactive Bladder | Vertebrobasilar Insufficiency | Pancytopenia | Delirium | Renal Hypouricemia | CHOPS Syndrome | Sclerocornea | Distal Spinal Muscular Atrophy | Zimmermann-Laband Syndrome | Erectile Dysfunction | Kaposi Sarcoma | Snyder-Robinson Syndrome | Galloway-Mowat Syndrome | Cardiofaciocutaneous Syndrome | Tinea Versicolor | Endometritis | Jaundice, Obstructive | Heterotaxy | Lymphoma Lymphoblastic | Glutaric Aciduria Type 2 | Glaucomatocyclitic Crisis | Early Infantile Epileptic Encephalopathy 28 | Hyperlipidemia | Sickle Cell Disease | Camptocormia | 5-oxoprolinase Deficiency | Neurofibrosarcoma | Antley-Bixler Syndrome | Joubert Syndrome | Spondylolisthesis | Cystinuria | Neurofibromatosis Type 1 | Thyroiditis, Autoimmune | Zollinger-Ellison Syndrome | Periodontitis | Thanatophoric Dysplasia Type 1 | Cramp Fasciculation Syndrome | Cystinosis | Oligoasthenoteratozoospermia | Lymphedema | Demyelinating Diseases | Stroke, Hemorrhagic | Isovaleric Acidemia | Autoimmune Autonomic Ganglionopathy | Fibrosarcoma | COACH Syndrome | Light Chain Amyloidosis | Preaxial Polydactyly | Blepharoconjunctivitis | Hyper IgE Syndrome | Chronic Myeloid Leukemia | Osteogenesis Imperfecta Type III | Iron Overload | Hypopigmentation | Acute Myeloid Leukemia | Gingivitis | Myofibrillar Myopathy | Aneurysm, Abdominal Aortic | Pulmonary Stenosis | Chudley-McCullough Syndrome | Congenital Hemolytic Anemia | DICER1 Syndrome | Niemann-Pick Disease | Netherton Syndrome | Becker Muscular Dystrophy | Progressive Myoclonic Epilepsy | Spinocerebellar Ataxia Type 13 | Pulverulent Zonular Cataract | T-cell Leukemia | Localized Scleroderma | IMAGe Syndrome | Centronuclear Myopathy | DOCK8 Immunodeficiency Syndrome | Hypersensitivity | Pseudo-pseudohypoparathyroidism | Allergic Contact Dermatitis | Craniolenticulosutural Dysplasia | Leri Pleonosteosis | Congenital Disorders Of Glycosylation | Kawasaki Disease | Familial Exudative Vitreoretinopathy | Liddle Syndrome | Cysticercosis | Mabry Syndrome | ICF Syndrome | Hyperuricemia | Myoclonic Atonic Epilepsy | Melanoma, Uveal | Transcobalamin Deficiency | Cryptosporidiosis | Dupuytren Disease | Juvenile Myelomonocytic Leukemia | Dyslexia | Birt-Hogg-Dube Syndrome | Chondromyxoid Fibroma | Neuronal Ceroid Lipofuscinosis | Spondylocarpotarsal Synostosis Syndrome | Mitochondrial Myopathy | Fibrosis | Spinal Muscular Atrophy Type 2 | Sandhoff Disease | Polyradiculopathy | Best Macular Dystrophy | Glucagonoma | Anterior Segment Dysgenesis | Aspartylglycosaminuria | HUPRA Syndrome | Osteopetrosis | Spinal Muscular Atrophy | Glanzmann Thrombasthenia | Pilomatrix Carcinoma | Pure Autonomic Failure | L-2-Hydroxyglutaric Aciduria | Leukoplakia | Atrial Septal Defect | Paraganglioma, Carotid Body | Patent Foramen Ovale | Bartter Syndrome | Headache | Porencephaly | Brenner Tumor | Retinal Dystrophy, Early-onset Severe | Esophageal Adenocarcinoma | Congenital Myopathy | Schaaf-Yang Syndrome | Pneumoconiosis | Lassa Fever | Congenital Torticollis | Charcot-Marie-Tooth Disease Type 2E | Systemic Mastocytosis | Neutrophilia | Fibromuscular Dysplasia | Diamond-Blackfan Anemia | Dysgerminoma | Focal Cortical Dysplasia Type 2 | Muscle Wasting | Generalized Epilepsy With Febrile Seizures Plus | Vitamin D Deficiency | Acne | Optic Nerve Hypoplasia, Bilateral | Norrie Disease | Hepatic Adenomatosis | Hyperthyroidism | Adenoma, Villous