Osteogenesis Imperfecta Type III

About the Disease
Osteogenesis Imperfecta, Type Iii, also known as osteogenesis imperfecta type iii, is related to osteogenesis imperfecta, type v and osteogenesis imperfecta, type xv. An important gene associated with Osteogenesis Imperfecta, Type Iii is COL1A2 (Collagen Type I Alpha 2 Chain), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. The drugs Zoledronic acid and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and bone marrow, and related phenotypes are frontal bossing and scoliosis

Common Targets
COL1A1 | BMP1 | P3H1 | FKBP10 | COL1A2 | CREB3L1 | IFITM5 | CRTAP | WNT1 | SERPINF1

Note: If you'd like to get a target analysis report for Osteogenesis Imperfecta Type III, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Osteogenesis Imperfecta Type III at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Behavioral Variant Of Frontotemporal Dementia | Thrombasthenia | Hypercalciuria | Neurocysticercosis | Congenital Myasthenic Syndrome | Pierpont Syndrome | Stroke, Hemorrhagic | Depression | Acral Lentiginous Melanoma | Placenta Previa | Hepatic Steatosis | Neuroectodermal Tumors, Primitive | Retinoschisis | Hairy Cell Leukemia | Osteoporosis-pseudoglioma Syndrome | Vitamin K Deficiency | Pelvic Inflammatory Disease | Genee-Wiedemann Syndrome | Glioblastoma | Bethlem Myopathy | Pemphigus Vulgaris | Paroxysmal Nocturnal Hemoglobinuria | Epidermolysis Bullosa Simplex, Generalized | Anorectal Malformations | Filariasis | Mood Disorder | Lymphoma | Long QT Syndrome Type 1 | Aspartylglycosaminuria | Diabetic Macular Edema | Paronychia | Dyslipidemia | Pseudoachondroplasia | Granuloma Annulare | Lymphoma, AIDS-related | Zygomycosis | Cold Agglutinin Disease | Polyomavirus Nephropathy | Cyclic Vomiting Syndrome | Gastroschisis | Multiple Epiphyseal Dysplasia | Antithrombin III Deficiency | Protein S Deficiency | Alopecia | Hypotonia-cystinuria Syndrome | Stiff-man Syndrome | Keratitis | Pachyonychia Congenita | Adenoma, Villous | Craniopharyngioma | Acromicric Dysplasia | PASLI Disease | Subcortical Band Heterotopia | ADNP Syndrome | Obesity | Aromatic L-amino Acid Decarboxylase Deficiency | Pituitary Disorders | Smoldering Myeloma | Vaginitis | Stargardt Disease | Hyperandrogenemia | Anorchia | Schistosomiasis Mansoni | Turner's Syndrome | Papilledema | 3-M Syndrome | Kidney Stones | Acrodermatitis Enteropathica | Shock, Cardiogenic | Hennekam Lymphangiectasia-lymphedema Syndrome | Spondyloepiphyseal Dysplasia Tarda, X-linked | Urofacial Syndrome | Hypercholesterolemia, Familial | Giant Cell Arteritis | Hypertension, Essential | Eccrine Porocarcinoma | Priapism | Hydrocephalus, Normal Pressure | Fuchs Dystrophy | Juvenile Xanthogranuloma | Distal Myopathy | Hyperbilirubinemia | Glycogen Storage Disease Type 0, Muscle | Joubert Syndrome | Mosaic Variegated Aneuploidy Syndrome 2 | Arthritis, Reactive | Pseudo-pseudohypoparathyroidism | Acute Anterior Uveitis | Congenital Dyserythropoietic Anemia | Phenylketonuria | Mitochondrial Cytopathy | Kaposiform Hemangioendothelioma | Lewy Body Dementia | Urolithiasis | Atrioventricular Septal Defect | Stuve-Wiedemann Syndrome | Erythema Nodosum | Erectile Dysfunction | Split Hand-foot Malformation | Wiskott-Aldrich Syndrome | Osteoglophonic Dysplasia | Macrophagic Myofasciitis | Congenital Mirror Movements | Sarcoma | Bronchitis | Fabry's Disease | Spinal Muscular Atrophy Type 3 | Lyme Disease | Nephrocalcinosis | Facioscapulohumeral Muscular Dystrophy Type 1 | Klippel-Feil Syndrome | Aplastic Anemia | Roberts Syndrome | Autoimmune Polyendocrine Syndrome | Intermittent Claudication | Spondylocostal Dysostosis | Adenosine Deaminase 2 Deficiency | Oral Lichen Planus | Toxic Epidermal Necrolysis | Behcet's Disease | Acrodysostosis | Aldosterone Synthase Deficiency | Bladder Exstrophy | Hepatitis E | Primary Cutaneous Amyloidosis | Dowling-Degos Disease | Blepharo-cheilo-odontic Syndrome | Membranous Nephropathy | Conjunctivitis | Anxiety Disorders | Mabry Syndrome | Diverticulitis | Epidermolytic Palmoplantar Keratoderma | Spinocerebellar Ataxia Type 10 | Palmoplantar Keratoderma | Ebstein Anomaly | Speech Disorders | Bacterial Meningitis | Sclerosteosis | Seborrheic Dermatitis | Primary Pigmented Nodular Adrenocortical Disease | Pilomatrix Carcinoma | Best Macular Dystrophy | Sleep Apnea, Central | Protein C Deficiency | Seasonal Mood Disorder | Retinitis Pigmentosa 3 | Splenomegaly | Rolandic Epilepsy | Blomstrand Osteochondrodysplasia | Early Infantile Epileptic Encephalopathy 28 | Pulmonary Alveolar Proteinosis | Melanoma | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Analgesia | Scabies | Lesch-Nyhan Syndrome | Primary Familial Brain Calcification | Multiple Hamartoma Syndrome | Fascioliasis | Agranulocytosis | Arteriosclerosis | Intestinal Hypomagnesemia 1 | Hypopigmentation | Trichotillomania | Thanatophoric Dysplasia Type 1 | Angiosarcoma | Hyperlipidemia | Biotinidase Deficiency | Esophagitis, Eosinophilic | Porphyria Cutanea Tarda | Gliosarcoma | Herpes Simplex Dermatitis | Macular Corneal Dystrophy | Oligospermia | Auriculocondylar Syndrome | Ophthalmia, Sympathetic | Pure Red Cell Aplasia | Heavy Chain Disease | Occipital Neuralgia | Neurofibromatosis-Noonan Syndrome | Nasodigitoacoustic Syndrome | Carcinoma, Small Cell | Chronic Kidney Disease | Dwarfism | Adenomatoid Tumor | 3C Syndrome | Fibrosis | Transthyretin-related Amyloidosis | GLUT1 Deficiency Syndrome | Non-proliferative Diabetic Retinopathy | Chondromyxoid Fibroma | Hypertension | Salla Disease | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Autoimmune Autonomic Ganglionopathy | Vitelliform Macular Dystrophy | Hyperbilirubinemia, Neonatal | Metachondromatosis | Pernicious Anemia | Knobloch Syndrome | Loeys-Dietz Syndrome Type 4 | Charcot-Marie-Tooth Disease Type 2D | Vascular Calcification | Amenorrhea | Epidermolysis Bullosa Simplex, Localized | Chronic Myeloid Leukemia | Neurofibromatosis Type 2 | Saul-Wilson Syndrome | Aplasia Cutis Congenita | Fibromuscular Dysplasia | Trichomegaly | Renal Dysplasia | Craniofrontonasal Syndrome | Schwartz-Jampel-Aberfeld Syndrome | Endometritis | Steel Syndrome | Retinal Diseases | Porphyria | Oligoastrocytoma | Keratopathy | Cardiofaciocutaneous Syndrome | Chromosome 9q34.3 Deletion Syndrome | Familial Hyperaldosteronism | Progressive Familial Intrahepatic Cholestasis Type 3 | Cryopyrin-associated Periodic Syndromes | Creatine Deficiency Syndrome Due To AGAT Deficiency | Pleomorphic Xanthoastrocytoma | Glucagonoma | Plasma Cell Leukemia | Osteoarthritis | Epithelial-myoepithelial Carcinoma | Walker-Warburg Syndrome | Plasma Cell Dyscrasia | Congenital Disorders Of Glycosylation | Leukocyte Adhesion Deficiency | Hereditary Mixed Polyposis Syndrome | Hyperthermia, Malignant | Cholangitis | Osteopetrosis | Gastroenteritis, Eosinophilic | L-2-Hydroxyglutaric Aciduria | Androgen Insensitivity | Fanconi Anemia | Hemolytic Uremic Syndrome | Vertigo | Hyperuricemia | Gastric Atrophy | Persistent Truncus Arteriosus | HUPRA Syndrome | Androgenic Alopecia | Gout | Spitzoid Melanoma | Fraser Syndrome | Cardiomyopathy, Dilated, 1L | Peripheral Neuropathy | Panniculitis | Holt-Oram Syndrome | Molybdenum Cofactor Deficiency | Gastritis | Hypobetalipoproteinemias | Facioscapulohumeral Muscular Dystrophy | Multicentric Carpotarsal Osteolysis Syndrome | Hartsfield Syndrome | Familial Mediterranean Fever | VACTERL Association | Ameloblastic Carcinoma | Stuttering | Congenital Poikiloderma | Ileitis | Astigmatism | Epidermolysis Bullosa Acquisita | Juvenile Myoclonic Epilepsy | Glomerulonephritis | Low Tension Glaucoma | Fibrillation, Atrial | Angiomyolipoma | Hepatitis D | Arthritis, Psoriatic | Hypertension, Renovascular | Temporal Lobe Epilepsy | Cryptococcal Meningitis | Haim-Munk Syndrome | Basal Ganglia Disease | ICF Syndrome | Budd-Chiari Syndrome | Stroke, Ischemic | Waardenburg Syndrome Type 2A | Nephrosclerosis | Ureteropelvic Junction Obstruction | Overactive Bladder | Martsolf Syndrome | Greenberg Dysplasia | Spondyloperipheral Dysplasia | Tonsillitis | Tuberculous Meningitis | Alpers Syndrome | Lysosomal Acid Lipase Deficiency | Vitamin A Deficiency | COACH Syndrome | Spinal And Bulbar Muscular Atrophy | Malonyl-CoA Decarboxylase Deficiency | Chondrodysplasia Punctata | Alkaptonuria | Focal Cortical Dysplasia Type 2 | Lymphoproliferative Disorders | Mucolipidosis Type III | Herpes Genitalis | Oculocutaneous Albinism | Low Phospholipid Associated Cholelithiasis | Chanarin-Dorfman Syndrome | Encephalopathy, Glycine | Bone Giant Cell Tumor | Juvenile Hyaline Fibromatosis | Barrett Esophagus | Rash | Cerebrotendinous Xanthomatosis | Interstitial Lung Diseases | Nephrotic Syndrome Type 1 | Ichthyosis Hystrix, Curth-Macklin Type | Epidermolytic Hyperkeratosis | Micro Syndrome | Spondylo-ocular Syndrome | Skin Fragility-woolly Hair Syndrome | Corneal Ulcer | Connective Tissue Disorders | Spinocerebellar Ataxia Type 21 | C3 Glomerulonephritis | T-cell Chronic Lymphocytic Leukemia | Amyloidosis | Cancer, Brain | Hemophilia | Mitochondrial DNA Depletion Syndrome | Disseminated Intravascular Coagulation | Desmosterolosis | Thalassemia, Beta | Gestational Trophoblastic Disease | Blepharitis | Takenouchi-Kosaki Syndrome | Glycogen Storage Disease | Prune Belly Syndrome | Tietze Syndrome | Cholera | Pulmonary Vein Stenosis | Trachoma | Schuurs-Hoeijmakers Syndrome | Hepatitis | Antley-Bixler Syndrome | Robinow Syndrome | Hepatoblastoma | Chudley-McCullough Syndrome | Mitochondrial DNA Depletion Syndrome 13 | Multiple Sclerosis, Secondary Progressive | Myositis | Hashimoto Thyroiditis | Spinocerebellar Ataxia Type 42 | Spinocerebellar Ataxia Type 23 | Pheochromocytoma | Chromosome 16p11.2 Deletion Syndrome | Acute Motor Axonal Neuropathy | Spinocerebellar Ataxia Type 20 | Hepatitis, Autoimmune | Menkes Disease | Recurrent Respiratory Papillomatosis | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | B-cell Chronic Lymphocytic Leukemia | Pyruvate Kinase Deficiency | Geleophysic Dysplasia | Asphyxia Neonatorum | Hepatitis A | Dysferlinopathy | Trismus-pseudocamptodactyly Syndrome | Arrhythmogenic Right Ventricular Cardiomyopathy | Carcinoma In Situ | Meningioma | Diffuse Mesangial Sclerosis | Bietti Crystalline Dystrophy | Skin Papilloma | Arts Syndrome | Argininosuccinic Aciduria | Gallstones | Chronic Mucocutaneous Candidiasis | Vertebrobasilar Insufficiency | Syphilis | Pulmonary Stenosis | Glutaric Aciduria Type 1 | Pseudohypoaldosteronism | Gnathodiaphyseal Dysplasia | Spitz Nevus | Common Cold | Melnick-Needles Syndrome | MIRAGE Syndrome | Leri-Weill Dyschondrosteosis | Porphyria, Variegate | Malaria | Williams Syndrome | Muckle-Wells Syndrome | Colon Adenoma | Mucormycosis | Acrodermatitis