Osteogenesis Imperfecta Type III

About the Disease
Osteogenesis Imperfecta, Type Iii, also known as osteogenesis imperfecta type iii, is related to osteogenesis imperfecta, type v and osteogenesis imperfecta, type xv. An important gene associated with Osteogenesis Imperfecta, Type Iii is COL1A2 (Collagen Type I Alpha 2 Chain), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. The drugs Zoledronic acid and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and bone marrow, and related phenotypes are frontal bossing and scoliosis

Common Targets
COL1A1 | BMP1 | P3H1 | FKBP10 | COL1A2 | CREB3L1 | IFITM5 | CRTAP | WNT1 | SERPINF1

Note: If you'd like to get a target analysis report for Osteogenesis Imperfecta Type III, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Osteogenesis Imperfecta Type III at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Angioedema | Moyamoya Disease | LRBA Deficiency | Diverticulitis | Pain | Silicosis | Spinocerebellar Ataxia Type 38 | Smoldering Myeloma | Polymyositis | Discoid Lupus Erythematosus | Vitamin K Deficiency | Bursitis | Crohn's Disease | Dysmorphophobia | Brugada Syndrome 1 | Pelizaeus-Merzbacher Disease | Paraganglioma | Metaphyseal Chondrodysplasia, Schmid Type | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Irritable Bowel Syndrome | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Anemia | Beckwith-Wiedemann Syndrome | Infertility, Male | Congenital Hemolytic Anemia | Limb Girdle Muscular Dystrophy | Facioscapulohumeral Muscular Dystrophy | Primary Hyperoxaluria | Insulin Resistance | Myasthenia | Chiari Malformation Type I | Tularemia | Rhabdomyosarcoma, Alveolar | Hypereosinophilic Syndrome | Klippel-Feil Syndrome | Carbamoyl Phosphate Synthetase I Deficiency | Vascular Calcification | Myoclonus | Bone Marrow Necrosis | Joubert Syndrome | Spinocerebellar Ataxia Type 13 | Presbycusis | Juvenile Polyposis | Parkinson's Disease | Hyperekplexia | Pemphigoid | Autonomic Nervous System Disorders | Sarcoma, Endometrial Stromal | Bietti Crystalline Dystrophy | Charcot-Marie-Tooth Disease Type 3 | Trimethylaminuria | Spinocerebellar Ataxia | Leukocyte Adhesion Deficiency Type 1 | Congenital Hereditary Endothelial Dystrophy Type I | Rhabdomyosarcoma | Incontinentia Pigmenti | Peritonitis | Diabetes Insipidus, Nephrogenic | FG Syndrome | Tyrosinemia Type 1 | Cervicitis | Fascioliasis | Osteoporosis | Hypertensive Retinopathy | Low Phospholipid Associated Cholelithiasis | Scoliosis | Congenital Muscular Dystrophy | Light Chain Amyloidosis | Neurogenic Bladder | Histiocytic Sarcoma | Diabetes Gestational | Oguchi Disease-2 | Usher Syndrome Type III | Rubeosis Iridis | Non-Langerhans Cell Histiocytosis | Hepatitis C, Chronic | Hypopituitarism | Fetal And Neonatal Alloimmune Thrombocytopenia | Angiomyolipoma | Mast Cell Leukemia | Otosclerosis | Hyperlipidemia Type V | Ghosal Syndrome | Angioimmunoblastic T-cell Lymphoma | Spondylometaphyseal Dysplasia | Amyloidosis | Menkes Disease | Wagner Disease | Spondyloepiphyseal Dysplasia Tarda, X-linked | Carcinoma, Signet Ring Cell | Lipoma | Schizophrenia, Paranoid | Leukodystrophies | Leukoplakia | Congenital Dyserythropoietic Anemia | Cole-Carpenter Syndrome | Meleda Disease | Fetal Alcohol Syndrome | Lentigo | Monilethrix | Hypertension, Renal | HIBCH Deficiency | Retinal Vasculitis | Cancer, Bladder | Hypercalciuria | Impetigo | Johanson-Blizzard Syndrome | Aphasia | SAPHO Syndrome | Sorsby Fundus Dystrophy | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Absence Epilepsy | Parkinson Disease 6, Autosomal Recessive Early-onset | Cutaneous Angiosarcoma | Myocardial Infarction | Thrombotic Microangiopathy | Cartilage Disorders | Small Lymphocytic Lymphoma | Hypertension, Pulmonary | Marshall-Smith Syndrome | Anorchia | Charcot-Marie-Tooth Disease | Common Cold | Nemaline Myopathy 8 | Cerebellar Ataxia, Cayman Type | Acute Chest Syndrome | Congenital Stromal Corneal Dystrophy | Mosaic Variegated Aneuploidy Syndrome 2 | Adult Polyglucosan Body Disease | Depression | Progressive External Ophthalmoplegia | Tuberculous Meningitis | Amenorrhea | Bacterial Meningitis | Osteomyelitis | Inflammatory Myofibroblastic Tumor | Olmsted Syndrome | Medulloblastoma | Charcot-Marie-Tooth Disease, Type 2A | Familial Pheochromocytoma-paraganglioma | Lyme Disease | Hyperparathyroidism | Tic Disorder | Neurotoxicity | Pearson Syndrome | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Meningioma, Benign | Cohen Syndrome | Cardiospondylocarpofacial Syndrome | Apraxia | Multiple Hamartoma Syndrome | MIRAGE Syndrome | Retinal Degeneration | Nasodigitoacoustic Syndrome | Peripheral Neuropathy | Chromosome 8q21.11 Deletion Syndrome | Knobloch Syndrome | Postpartum Depression | Polyradiculopathy | Hypotension, Orthostatic | Reye Syndrome | Acrocallosal Syndrome | Galactosemia | Otitis Externa | Nephrocalcinosis | Hypertension, Renovascular | Microphthalmia, Syndromic 7 | Neurofibrosarcoma | Amelanotic Melanoma | Nanophthalmos | 3C Syndrome | Hyperinsulinemic Hypoglycemia | Obsessive-compulsive Disorder | Retinitis Pigmentosa 3 | Coronary Restenosis | Immunoproliferative Disorders | Ischemia | Nephropathy | Ataxia-ocular Apraxia 2 | Diabetic Encephalopathy | Non-bullous Congenital Ichthyosiform Erythroderma | Epidermolytic Ichthyosis, Annular | Chloridorrhea, Congenital | Apert Syndrome | Chromosome 16p11.2 Deletion Syndrome | Panuveitis | Riboflavin Transporter Deficiency Neuronopathy | Holt-Oram Syndrome | Dyggve-Melchior-Clausen Disease | Lymphedema | DNA Ligase IV Deficiency | Metachromatic Leukodystrophy | Coenzyme Q10 Deficiency | Bladder Exstrophy | Hypolipoproteinemia | Carcinoma, Merkel Cell | Autoimmune Polyendocrinopathy Syndrome Type I | High Molecular Weight Kininogen Deficiency | Corneal Dystrophy | Pierre Robin Syndrome | ICF Syndrome | Trismus-pseudocamptodactyly Syndrome | Infectious Diarrhea | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Pterygium | Progressive Myoclonic Epilepsy | Hypohidrotic Ectodermal Dysplasia | Argininosuccinic Aciduria | Porphyria, Variegate | Combined Malonic And Methylmalonic Acidemia | Familial Advanced Sleep Phase Syndrome | Myosin Storage Myopathy | Bullous Pemphigoid | Hydronephrosis | Headache | Wieacker-Wolff Syndrome | Glutaric Aciduria Type 3 | Dementia | Hereditary Spherocytosis | Glutathione Synthetase Deficiency | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Carotid Artery Disease | Stromal Corneal Dystrophy | Lathosterolosis | Melanocytic Nevus | Osteosclerosis | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Dent Disease | Congenital Mirror Movements | Ovarian Sex Cord-stromal Tumor | Ornithine Transcarbamylase Deficiency | IgA Deficiency | Hypocalcemia | Acne Vulgaris | Pancreatitis, Chronic | Prolactinoma | Familial Hyperaldosteronism | Ganglioneuroma | Exocrine Pancreatic Insufficiency | Vulvovaginitis | Guanidinoacetate Methyltransferase Deficiency | Focal Cortical Dysplasia Type 2 | Tracheal Disorders | Eating Disorder | Smith-Kingsmore Syndrome | Benign Familial Pemphigus | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Retinopathy Of Prematurity | Epidermolysis Bullosa Simplex | Polymyalgia Rheumatica | Emery-Dreifuss Muscular Dystrophy | Rhabdomyosarcoma, Embryonal | NDH Syndrome | Congenital Afibrinogenemia | Nephrotic Syndrome | Pulmonary Vein Stenosis | Proteus Syndrome | Hypogammaglobulinemia | Shprintzen-Goldberg Syndrome | Renal Tubular Acidosis | Neurofibromatosis-Noonan Syndrome | LMNA-related Congenital Muscular Dystrophy | Inflammatory Joint Disease | Hyperhomocysteinemia | Iron Overload | Angelman Syndrome | Batten Disease | Thrombocytopenia | Usher Syndrome Type I | Lewy Body Dementia | Osteogenesis Imperfecta Type III | Acute Kidney Injury | Paraganglioma, Carotid Body | X-linked Myotubular Myopathy | Spermatocele | Epidermolysis Bullosa Dystrophica | Multiple Sclerosis, Primary Progressive | Gerstmann-Straussler-Scheinker Syndrome | Hypogonadism | Chronic Myeloid Leukemia | Crouzon Syndrome With Acanthosis Nigricans | Primary Biliary Cholangitis | Hypoplastic Left Heart Syndrome | Calcium Pyrophosphate Deposition Disease | Encephalopathy, Ethylmalonic | Hereditary Xerocytosis | Epilepsy Of Infancy With Migrating Focal Seizures | Mitochondrial Myopathy | Pseudohypoparathyroidism Type 2 | Goldenhar Syndrome | Partington Syndrome | Diffuse Palmoplantar Keratoderma | Spinocerebellar Ataxia Type 3 | Keratosis | Chronic Granulomatous Disease, X-linked | Nephronophthisis | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Communication Disorders | Wolfram Syndrome 2 | Impulse Control Disorder | Prolymphocytic Leukemia | Polycystic Liver | Noonan Syndrome | Primary Lateral Sclerosis | Nager Acrofacial Dysostosis | Binge Eating Disorder | Waardenburg Syndrome | Leishmaniasis, Cutaneous | Lichen Sclerosus | Sleep Disorder | Glomerulonephritis, Membranous | Leber Congenital Amaurosis | Lymphopenia | Hemophagocytic Lymphohistiocytosis | Glycogen Storage Disease Type 1a | Non-small Cell Lung Cancer | Sick Sinus Syndrome | Xeroderma Pigmentosum | Autoimmune Autonomic Ganglionopathy | Brooke-Spiegler Syndrome | Still Disease | Antenatal Bartter Syndrome Type 1 | Hyperparathyroidism, Primary | Leukocyte Adhesion Deficiency | Camptocormia | Erythromelalgia | Carpenter Syndrome | Primary Cutaneous Amyloidosis | Left Ventricular Noncompaction | Intracerebral Hemorrhage | Kearns-Sayre Syndrome | Exfoliative Dermatitis | Guttate Psoriasis | Hydrops Fetalis | Actinomycetoma | Chorea | Intestinal Obstruction | Disseminated Intravascular Coagulation | Chronic Granulomatous Disease | Generalized Epilepsy With Febrile Seizures Plus | Xeroderma Pigmentosum Variant Type | Myhre Syndrome | Oligoasthenoteratozoospermia | Hemorrhagic Disorders | Cousin Syndrome | Noonan Syndrome-like Disorder With Loose Anagen Hair | Anti-glomerular Basement Membrane Disease | Adrenal Insufficiency | GAPO Syndrome | Papilloma | Kawasaki Disease | Dermatofibrosarcoma | Neurocutaneous Melanocytosis | Primary Hyperoxaluria Type 1 | Lymphoma Lymphoblastic | Hydrocephalus, Normal Pressure | Liver Failure | Spinocerebellar Ataxia Type 40 | Protein C Deficiency | Dowling-Degos Disease | Chronic Periodontitis | Phenylketonuria | Congenital Aniridia | Plasma Cell Leukemia | Bone Giant Cell Tumor | Vitreoretinal Degeneration, Snowflake Type | Glucagonoma | Central Retinal Artery Occlusion | Pseudoachondroplasia | Adrenomyeloneuropathy | Cystitis | Conjunctivitis | Cancer, Lung | Feingold Syndrome | Gastrointestinal Disorders | Triple A Syndrome | Mood Disorder | Spinocerebellar Ataxia Type 17 | Hypercalcemia | Prune Belly Syndrome | Charcot-Marie-Tooth Disease Axonal Type 2N | Dysgerminoma | Disseminated Superficial Actinic Porokeratosis | Scapuloperoneal Spinal Muscular Atrophy | Primary Erythromelalgia | Von Willebrand Disease | Pyruvate Dehydrogenase Deficiency | Choriocarcinoma | Lymphoma, B-cell | Canavan Disease | Cenani-Lenz Syndactyly Syndrome | Kaposiform Hemangioendothelioma | Erysipelas | Leber Hereditary Optic Neuropathy | Acute Tubular Necrosis | Psoriasis | Cerebrotendinous Xanthomatosis | McCune-Albright Syndrome | Diffuse Mesangial Sclerosis | Keratocystic Odontogenic Tumor