Disease

Osteogenesis Imperfecta Type III

About the Disease
Osteogenesis Imperfecta, Type Iii, also known as osteogenesis imperfecta type iii, is related to osteogenesis imperfecta, type v and osteogenesis imperfecta, type xv. An important gene associated with Osteogenesis Imperfecta, Type Iii is COL1A2 (Collagen Type I Alpha 2 Chain), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. The drugs Zoledronic acid and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and bone marrow, and related phenotypes are frontal bossing and scoliosis

Common Targets
COL1A1 | BMP1 | P3H1 | FKBP10 | COL1A2 | CREB3L1 | IFITM5 | CRTAP | WNT1 | SERPINF1

疾病靶点研报
Osteogenesis Imperfecta Type III

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