Disease

Nephrogenic Diabetes Insipidus

About the Disease
Nephrogenic Diabetes Insipidus, also known as vasopressin-resistant diabetes insipidus, is related to diabetes insipidus, nephrogenic, 2, autosomal and x-linked nephrogenic diabetes insipidus. An important gene associated with Nephrogenic Diabetes Insipidus is AVPR2 (Arginine Vasopressin Receptor 2), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Aquaporin-mediated transport. The drugs Lithium carbonate and Amiloride have been mentioned in the context of this disorder. Affiliated tissues include kidney, pituitary and bone marrow, and related phenotypes are nephrogenic diabetes insipidus and hyposthenuria

Common Targets
G3630 | CA1 | AVPR2 | PDE5A | cAMP-Dependent protein kinase (PKA) | AQP2 | CA2 | CA9 | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | AMP-activated protein kinase (AMPK) | CALCR | A-Kinase Anchor Proteins (nonspecified subtype)

疾病靶点研报
Nephrogenic Diabetes Insipidus

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