Dwarfism

About the Disease
Isolated Growth Hormone Deficiency, Type Ia, also known as isolated growth hormone deficiency type ia, is related to microcephalic osteodysplastic primordial dwarfism, type i and seckel syndrome, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Isolated Growth Hormone Deficiency, Type Ia is GH1 (Growth Hormone 1), and among its related pathways/superpathways are G-protein signaling_RhoA regulation pathway and Neural Stem Cells and Lineage-specific Markers. The drugs Letrozole and Anastrozole have been mentioned in the context of this disorder. Affiliated tissues include pituitary, bone and brain, and related phenotypes are hypoglycemia and depressed nasal ridge

Common Targets
TBX22 | ARID1B | ORC6 | POC1A | TRPV4 | FGFR3 | DDR2 | G3479 | IGFALS | GH1 | SHOX | CDT1 | ORC1 | FAM111A | LARP7 | RNU4ATAC | ORC4 | NIN | PTDSS1 | GHR | CEP63 | GPR101 | PLK4 | ATR | COL2A1 | CDC6 | NPR2 | IQSEC2 | TRIM37

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Other Diseases

Nephrosclerosis | Syphilis | Myotonia | Thin Basement Membrane Disease | Myoclonus-dystonia Syndrome | Microcephalic Primordial Dwarfism | Phenylketonuria II | Congenital Hemolytic Anemia | Tenosynovial Giant Cell Tumor | Methemoglobinemia Type IV | Saul-Wilson Syndrome | HIBCH Deficiency | McKusick Type Metaphyseal Chondrodysplasia | Scleroderma | Malaria, Cerebral | Mitochondrial Disease | Hyperuricemic Nephropathy, Familial Juvenile | Hoyeraal-Hreidarsson Syndrome | Familial Advanced Sleep Phase Syndrome | Cohen Syndrome | Hyperacusis | Netherton Syndrome | Poretti-Boltshauser Syndrome | Asphyxia Neonatorum | Ocular Surface Squamous Neoplasia | Wieacker-Wolff Syndrome | Donnai-Barrow Syndrome | Multiple Sulfatase Deficiency | Metachondromatosis | Acromesomelic Dysplasia | Intermittent Explosive Disorder | Ovarian Sex Cord-stromal Tumor | Ichthyosis | Cherubism | Spinocerebellar Ataxia Type 20 | Pituitary Disorders | Osteoporosis, Postmenopausal | Left Ventricular Noncompaction | Acute Myeloid Leukemia | Vici Syndrome | Synovitis | Lymphedema-distichiasis Syndrome | Albinism | Optic Nerve Hypoplasia, Bilateral | Vitreoretinopathy, Proliferative | Schindler Disease | Farber Disease | Hemorrhage | Peripheral T-cell Lymphoma | Chiari Malformation Type I | Portal Vein Thrombosis | Spinocerebellar Ataxia Type 7 | Waardenburg Syndrome Type 2A | Osteomalacia | Mesothelioma, Malignant | Arthritis | Rhabdoid Tumor | Arthrogryposis | Colitis, Microscopic | Angiodysplasia | Acute Lymphocytic Leukemia | Dysequilibrium Syndrome | Cystinosis | VACTERL Association | Bethlem Myopathy | Sotos Syndrome | Paronychia | Osteoporosis-pseudoglioma Syndrome | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Vascular Cognitive Impairment | Glomerulonephritis, Membranous | Stickler Syndrome | Centronuclear Myopathy | Sandhoff Disease | Angiosarcoma Of The Breast | Japanese Encephalitis | Cholera | Kernicterus | Diabetes Insipidus | Heart Failure | Phenylketonuria | Porphyria | Richter's Syndrome | Encephalopathy, Ethylmalonic | Lysosomal Acid Lipase Deficiency | Ischemia | Extramammary Paget's Disease | Microphthalmia, Syndromic 7 | Borjeson-Forssman-Lehmann Syndrome | Actinomycetoma | Knobloch Syndrome | Spasticity | Hermansky-Pudlak Syndrome | Pulverulent Zonular Cataract | Cyclic Vomiting Syndrome | Arthritis, Psoriatic | Chronic Beryllium Disease | Colitis | NDH Syndrome | Leishmaniasis, Visceral | Superficial Spreading Melanoma | Neuroectodermal Tumors, Primitive | Tuberculosis | Carney Triad | Pulmonary Alveolar Microlithiasis | Alpha-1 Antitrypsin Deficiency | Incontinentia Pigmenti | Jaundice, Obstructive | Sarcosinemia | Eosinophilic Asthma | Klinefelter Syndrome | Demyelinating Diseases | Porencephaly | Diffuse Intrinsic Pontine Glioma | Orotic Aciduria | Biotinidase Deficiency | Currarino Syndrome | Medulloblastoma | Myocardial Infarction | Adrenoleukodystrophy, X-linked | Acute Tubular Necrosis | Juvenile Polyposis | Carpal Tunnel Syndrome | Mucolipidosis 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