Barrett Esophagus

About the Disease
Barrett Esophagus, also known as barrett's esophagus, is related to esophageal cancer and esophagus adenocarcinoma. An important gene associated with Barrett Esophagus is ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1), and among its related pathways/superpathways are Disease and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. The drugs Dexlansoprazole and Lansoprazole have been mentioned in the context of this disorder. Affiliated tissues include small intestine, skin and bone, and related phenotypes are esophageal ulceration and gastroesophageal reflux

Common Targets
BABAM1 | LOC105370455 | AFG3L1P | HEATR3 | LINC02257 | PAX9 | CEBPE | CCDC26 | THBS1 | CSMD3 | DCLRE1B | TAB2 | ZBTB38 | LOC105370500 | APOM | MGST1 | LOC105372985 | MPV17L | P2RY1 | HOXD4 | DTX3 | KCNC1 | G7157 | TAFA5 | LINC00824 | PTPRD | AKAP12 | KCNN3 | ZNF521 | CCND2 | G1029 | EMBP1 | CDYL2 | LINC00208 | GRIK1 | G7124 | ARHGEF26 | DIO3 | MCOLN2 | MLPH | FAT4 | LOC107986930 | POLD3 | G1950 | MYH10 | TYR | INSM1 | RUNX3 | IKZF1 | CPLANE1 | LEF1 | CDKN2B | STXBP4 | SFMBT2 | RGS17 | CASC11 | NRG1 | DMRT1 | MICA-AS1 | PADI6 | WNT9A | IRX3 | ZNF625 | ZEB2 | LRFN2 | BMP3 | CASC8 | PSCA | CTD-2194D22.4 | ZNF649 | SLC18A3 | CCKBR | RDX | CACNA1G | TCEAL7 | ST6GAL1 | CTNNA2 | SLC14A1 | OGG1 | SP140 | SCARB1 | SLC22A3 | LIN28B | LINC01572 | AP4B1 | LOC107987449 | G4609 | LOC105377732 | NOTCH4 | BTNL2 | BAK1 | PIGU | FLACC1 | ENG | PDZRN3 | LOC107987459 | TMOD1 | G2099 | RALY | CACNB2 | CDKN2B-AS1 | SLC15A1 | PDGFD | TIPARP | TSBP1-AS1 | NEUROG1 | TNFRSF19 | EEFSEC | KCNN4 | TACC3 | COLCA1 | NTRK3 | FAT3 | KITLG | FHIT | TMEFF2 | NR5A2 | CASP8 | LOC105377871 | G999 | XXYLT1 | LOC105369367 | TP63 | VSIG10L | PHLDB1 | HAGLROS | CCHCR1 | PLEKHM1 | GDF7 | SMAD7 | LOC105373874 | CD200 | IRF4 | NDRG4 | VPS53 | EYA4 | ARID5B | EHBP1 | PLCE1 | TET2 | ULK4 | HUNK | HACE1 | Interleukin-12 (IL-12) | RNF146 | HYKK | KCNK13 | PTPDC1 | OBSL1 | FERMT2 | HELQ | EPHA3 | ADH1B | G4233 | CASC17 | MECOM | CASC21 | MMP7 | LOC105369705 | ZGPAT | DNAH11 | MTMR3 | BACH1 | SP110 | EBF2 | DIRC3 | ELMO1 | LGR6 | DAPK1 | SLC4A7 | CCAT2 | LOC105374265 | LSP1 | ZNF569 | PLA2G6 | Vascular endothelial growth factor receptor (VEGFR) (nonspecified subtype) | G2064 | CDKN2A-DT | CAV1 | EBF1 | LONRF2 | MTAP | GPC5 | MAF | SKAP1 | ZNF655 | RIN3 | RTEL1 | LMX1B | NBEA | CSNK1A1 | STAT4 | PSORS1C1 | SLC22A18 | RHPN2 | ANKLE1 | G1956 | FGF10 | DLX2-DT | EMID1 | SST | SLC6A4 | LMTK2 | NSF | LOC107984214 | KLF7 | CD1D | VANGL2 | PRNCR1 | IGFBP-AS1 | PTPRT | ACOXL | AFAP1 | PSORS1C2 | BPTF | SRP14-DT | CHRNA3 | LINC01162 | CCDC170 | LOC105378460 | LOC107984363 | TSHR | IFNG | HAGLR | MYOCD | TPPP | ADH7 | MSMB | ZNF506 | STK33 | MX2 | ZBTB20 | AFAP1-AS1 | RBP3 | ZNF365 | ZNF345 | PREX2 | LOC105376400 | ERBB4 | CRTC1 | GJC2 | NAA25 | CLPTM1L | CHST9 | DCBLD2 | ARHGEF5 | CNTNAP2 | EXOC1 | RAB31 | MGMT | LOC105372093 | POU2AF3 | Gastric H+/K+-ATPase | PCAT19 | AFF3 | IRF8 | APC | CHMP4C | RUNX1 | CNBD1 | B3GAT2 | LOC105376536 | PCAT2 | LOC105372225 | FARP2 | GATA3 | FTO | ARMC2 | APOB | SFRP1 | G7015 | CDK10 | NELL1 | LRP1B | CBX7 | RFX6 | Arginase (nonspecified subtype) | IL13 | G472 | TWIST1 | SLC24A3 | G238 | GLP1R | RRAD | LOC105374875 | PRKD2 | LOC105370003 | G596 | PIP4K2A | ZNF793 | LMO1 | MAFB | CHEK2 | MLH1 | MICA | PITX1-AS1 | GRHL1 | FSTL1 | SLIT1 | ABCC3 | ROR2 | CEP72 | BARD1 | KIF1B | CTXND2 | LOC105370113 | HNF1B | MRTFA | EPAS1 | TFPI2 | LINC02627 | CCND2-AS1 | TGFBR2 | BARX1 | KIT | ATP2B4 | LINC00506 | HNF4G | TCF7L2 | MLLT10 | ELL | ODC1 | IGF2 | VTI1A | FENDRR | NBAT1 | ATPase (nonspecified subtype) | CTNND2 | DCC | TNFRSF13B | TMEM150C | TAC1 | ROBO2 | THADA | RTEL1-TNFRSF6B | ATF7IP | FAM78A | RAD51B | OPLAH | PDE4D | RIN2 | VAV3 | CASC15 | LOC105372710 | RUNDC3B | ITPR1 | XBP1 | ZNF254 | RGN | MC1R | MDM4 | FGFR2 | TRIM8 | G5562 | PEX14 | MYNN | HAAO | CDH13 | SH3GL3 | LOC105372815 | PDLIM5 | ITGA6 | CASC16 | GDNF | BAG6 | TNKS | AFM | SDR42E1 | PRDM5 | LAMA5

Note: If you'd like to get a target analysis report for Barrett Esophagus, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Barrett Esophagus at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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