Hereditary Angioedema

About the Disease
Angioedema, Hereditary, 1, also known as hereditary angioneurotic edema, is related to angioedema, hereditary, 3 and epiglottitis, and has symptoms including abdominal pain, diarrhea and vomiting. An important gene associated with Angioedema, Hereditary, 1 is SERPING1 (Serpin Family G Member 1), and among its related pathways/superpathways are Innate Immune System and Response to elevated platelet cytosolic Ca2+. The drugs Ciprofloxacin and Metronidazole have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and small intestine, and related phenotypes are muscle weakness and periorbital edema

Common Targets
BDKRB2 | HS3ST6 | C1S | G7124 | NR3C1 | F2 | PLG | G367 | Serine protease (nonspecified subtype) | Kallikrein (nonspecified subtype) | F5 | Complement Complex | F11 | ANGPT1 | KLKB1 | SERPING1 | F12

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