Hereditary Corneal Dystrophies

About the Disease
Granular Corneal Dystrophy, also known as familial hereditary corneal degeneration, is related to corneal dystrophy, groenouw type i and corneal dystrophy, reis-bucklers type. An important gene associated with Granular Corneal Dystrophy is TGFBI (Transforming Growth Factor Beta Induced). The drugs Hyaluronic acid and Tetryzoline have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and myeloid, and related phenotypes are Negative genetic interaction between BLM-/- and BLM+/+ and vision/eye

Common Targets
CCSER2 | MYO7A | SPATA7 | GALNT4 | ZEB1 | POMGNT1 | KIAA1549 | CYP4V2 | PPRC1 | SLC4A11 | GBF1 | GUCA1A | CFAP43 | POC1B | DCN | ADGRA3 | DNAJC9 | ATP2B1 | VSX1 | TULP1 | EFEMP1 | ADGRV1 | Uncharacterized LOC102724782, transcript variant X2 | COL17A1 | POC1B-GALNT4 | EYS | IMPG1 | SEMA4A | RP1 | ARHGAP19 | RBP3 | USH2A | UBIAD1 | BTAF1 | OVOL2 | TACSTD2 | BMPR1A | SLIT1 | NEK2 | TGFBI | SLC24A1

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