Tuberculosis

About the Disease
Mycobacterium Tuberculosis 1, also known as tuberculosis, is related to pulmonary tuberculosis and miliary tuberculosis, and has symptoms including coughing, fever and pruritus. An important gene associated with Mycobacterium Tuberculosis 1 is MTBS1 (Mycobacterium Tuberculosis, Susceptibility To Infection By, 1), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Calcium carbonate and Etanercept have been mentioned in the context of this disorder. Affiliated tissues include lungs, lymph nodes and pericardium, and related phenotypes are fatigue and fever

Common Targets
CDK1 | IL4 | TLR1 | LOC101927745 | LOC105370481 | ITGA6 | HSP90B1 | Acetyl-CoA Carboxylases (ACC) (nonspecified subtype) | CARD8 | TGFBR2 | POLD1 | IL10 | IL18 | CD209 | CGAS | Proteasome Complex | MIR149 | MMP1 | APOM | DST | PKP3 | G5243 | IL22 | SPP1 | G6647 | NFKB1 | HCN3 | G7124 | PRC1 | HAMP | PDE4D | CTNNB1 | JAK1 | ASXL2 | G114548 | CDH13 | LINC02511 | DNA-Directed DNA Polymerase Complex | NISCH | PMP22 | HLA-DQB1 | G3576 | PREP | FAP | TLR8 | MADD | JAKMIP1 | Interleukin 17 (nonspecified subtype) | ETS2-AS1 | Carbonic Anhydrase (nonspecified subtype) | LRBA | IL12B | TPK1 | L-type voltage-dependent calcium channel complex | LRMDA | CD1A | CYTOR | MYD88 | JAK2 | IRGM | LRRK2 | BMP4 | ATP Synthase, H+ Transporting, Mitochondrial F0 complex | cGMP-Dependent Protein Kinase (nonspecified subtype) | ARMC9 | FCGRT | PARD3B | IFI16 | SLC39A11 | NR1H2 | Thioredoxin-disulfide reductase (TrxR) (nonspecified subtype) | G7015 | IL1B | UQCC6 | G6774 | Phospholipase A2 (nonspecified subtype) | NAT2 | Integrin alphavbeta3 (vitronectin) receptor | EPHX2 | IFIT5 | IFNGR1 | IL10RA | TOLLIP | FAM178B | GALNT13 | PKLR | DROSHA | ELANE | CA12 | GEMIN4 | NR1H3 | MMP3 | G6352 | MAP3K5 | ACE | G3569 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | PTPRG | LCK | LTA | TGFB1 | HLA-DQA1 | IL12RB1 | FPR1 | ALDH18A1 | IL4R | MRC1 | TYR | IL7R | IL10RB | MAOA | TYK2 | G5133 | CD3 Complex (T Cell Receptor Complex) | DLG2 | PCSK9 | CD14 | NOD2 | VSIG4 | G4780 | FOXP1 | G29126 | G7099 | POU2F3 | CELSR1 | MR1 | HLA-B | PTPRJ | CHD7 | IFNGR2 | IL-4 receptor | G6772 | DGCR8 | NR1I2 | TSC2 | ICAM1 | MASP2 | CA7 | TGM2 | G7852 | CD44 | LINC02885 | CTSZ | IL27 | SMURF1 | IL12RB2 | GATA2 | SP110 | CCR2 | HLA-DPA1 | CISH | SOD2 | MC3R | DUSP14 | HLA-DRB1 | AHSA2P | CD40 | IMPDH2 | FMO2 | Reverse transcriptase (Telomerase) | IL1R1 | LHCGR | LOC107984251 | PDGFRB | TSPO | LINC02618 | DDX43 | Pyruvate dehydrogenase kinase (nonspecified subtype) | IFIT1 | FCGR3A | XDH | DICER1 | Interferon (nonspecified subtype) | PTPN1 | STK3 | CD53 | TTC7A | ACHE | LOC105369749 | MBL2 | FDPS | PPARG | TCIRG1 | MALAT1 | ANO9 | MIR27A | PTPRU | Serine protease (nonspecified subtype) | HSD11B2 | TLR2 | MYLK | FAAH | AXIN2 | GLUL | STAT4 | BEST1 | ROR1 | L-Type calcium channel (nonspecified subtype) | LOC105374724 | IFNAR1 | MBP | IFITM3 | G2069 | IL12A | FPR2 | GLB1 | ATP-Binding Cassette (ABC) Transporter (nonspecified subtype) | IRF7 | PANK2 | TNFSF15 | CA2 | HERPUD1 | SPN | MMP8 | IL18R1 | AQP6 | CA5B | PCLAF | FASLG | LRIF1 | QPRT | Serine/Threonine-Protein Kinase PLK (nonspecified subtype) | LIPE | TENM4 | F2R | GAA | MSRA | PPM1A | DEFB1 | IL1R2 | SLCO1B1 | ASAP1 | FABP4 | MPP7 | NR3C1 | SFRP1 | LRP1B | METAP1 | G820 | SLC11A1 | DTYMK | SIRT3 | CA3 | TLR9 | ALB | VDR | CCL2 | ATP1A2 | AGO1 | LOC105370182 | ATPase (nonspecified subtype) | NOS2 | CLEC4E | GALR1 | TMEM50B | P2RX7 | FYN | LTA4H | DUT | PRKG1 | CCR5 | MIR196A2 | IFNG | ULK1 | GLA | ATR | alpha-Mannosidase (nonspecified subtype) | ALOX5 | MARCO | LIPG | MAOB | MIR499A | C10orf90 | KCND2 | FOXP3 | ATP synthase, H+ transporting, mitochondrial F1 complex | Monoamine oxidase (MAO) (nonspecified subtype)

Note: If you'd like to get a target analysis report for Tuberculosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Tuberculosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Purpura | Tremor | Polyarteritis Nodosa | Short-chain Acyl-CoA Dehydrogenase Deficiency | Migraine | Albinism | Dystrophy, Cone-rod | Fucosidosis | Nicolaides-Baraitser Syndrome | Hemorrhoids | Cataplexy | Leigh Syndrome | Lyme Disease | Measles | Acute Chest Syndrome | Waardenburg Syndrome Type 2A | Spinocerebellar Ataxia Type 23 | Intestinal Tuberculosis | Sarcoma, Endometrial Stromal | Pure Red Cell Aplasia | Werner's Syndrome | Pleomorphic Xanthoastrocytoma | Androgenic Alopecia | Lupus Erythematosus | Fibronectin Glomerulopathy | Ghosal Syndrome | Iron Metabolism Disorders | Esophageal Adenocarcinoma | Postpoliomyelitis Syndrome | Succinic Semialdehyde Dehydrogenase Deficiency | Sick Sinus Syndrome 1 | Mastitis | Myoclonus | Blepharoconjunctivitis | Juvenile Myoclonic Epilepsy | Schistosomiasis Mansoni | Malonyl-CoA Decarboxylase Deficiency | Renal Hypouricemia | Jawad Syndrome | Delirium | Pemphigus | Osteogenesis Imperfecta Type V | Peritonitis | Nephritis, Interstitial | Cancer, Lung | Gray Platelet Syndrome | Familial Hypobetalipoproteinemia | McKusick Type Metaphyseal Chondrodysplasia | Plasmacytoma | Fascioliasis | Non-Langerhans Cell Histiocytosis | Fibrodysplasia Ossificans Progressiva | Cancer, Bladder | Ameloblastic Carcinoma | Bone Giant Cell Tumor | Spinocerebellar Ataxia Type 14 | Combined Malonic And Methylmalonic Acidemia | Senior-Loken Syndrome | Spinocerebellar Ataxia Type 16 | Cannabis Abuse | Fetal Alcohol Syndrome | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Proximal Symphalangism | Carcinoma, Small Cell | Angiosarcoma Of The Breast | Aneurysm, Thoracic Aortic | Parapsoriasis | Benign Familial Neonatal Convulsions | Chiari Malformation Type I | Chondrodysplasia Punctata | Ulcerative Colitis | Cancer, Kidney | Hyperinsulinism-hyperammonemia Syndrome | Polymyalgia Rheumatica | Anti-glomerular Basement Membrane Disease | Pneumonia, Bacterial | 3-M Syndrome | Pyloric Stenosis, Infantile Hypertrophic | Anencephaly | Glycogen Storage Disease Type 6 | Neovascular Glaucoma | Pneumonia, Viral | Spinocerebellar Ataxia Type 5 | Craniofacial Dysostosis | Adult Polyglucosan Body Disease | Hyperkeratosis | Pyoderma Gangrenosum | Blue Nevus | Presbycusis | Gastroenteritis, Eosinophilic | Neurofibromatosis | Pseudoachondroplasia | Campomelic Dysplasia | Glomerulonephritis, Membranoproliferative | Neuroma | Hemophilia | Graves Disease | Microtia | Encephalocele | Myelomeningocele | Polymyositis | Central Core Disease | Hepatic Adenomatosis | Vici Syndrome | Pneumonia, Mycoplasma | Progressive Osseous Heteroplasia | Hypoglycemia | Thin Basement Membrane Disease | Basan Syndrome | Iron Deficiency Anemia | Diabetes Insipidus, Neurogenic | Dental Caries | Osteosarcoma | Chorea | Lipid Storage Myopathy | Echinococcosis | Schindler Disease | Autosomal Recessive Spastic Paraplegia Type 75 | Hypermethioninemia | Intestinal Hypomagnesemia 1 | Multiple Sclerosis, Secondary Progressive | Early Infantile Epileptic Encephalopathy | Sclerosteosis 2 | Dominant Optic Atrophy | Diabetes Gestational | 3-hydroxy-3-methylglutaric Aciduria | Coenzyme Q10 Deficiency | Pneumococcal Meningitis | ACTH-independent Macronodular Adrenal Hyperplasia | Pantothenate Kinase-associated Neurodegeneration | Uterine Leiomyoma | Ganglioglioma | Melnick-Needles Syndrome | Myositis, Focal | Localized Scleroderma | Parkinson Disease 6, Autosomal Recessive Early-onset | LEOPARD Syndrome | Schuurs-Hoeijmakers Syndrome | Hepatitis, Chronic | Uremic Pruritus | Wolff-Parkinson-White Syndrome | Charcot-Marie-Tooth Disease Type 4D | Megalencephaly | Congenital Hypofibrinogenemia | Lipid Storage Diseases | Oculodentodigital Dysplasia | Purpura, Thrombotic Thrombocytopenic | Pfeiffer Syndrome | Hypertensive Nephropathy | Takayasu's Arteritis | Robinow Syndrome | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Trichuriasis | Erythema Nodosum | Anal Fissure | Congenital Generalized Lipodystrophy | Restrictive Dermopathy | Light Chain Amyloidosis | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Carcinoma, Squamous Cell | Hereditary Sensory Neuropathy Type 1 | Blepharophimosis Syndrome | Cardiomyopathy, Dilated, 1L | Encephalopathy | Gardner Syndrome | Prolidase Deficiency | Obesity, Morbid | Oguchi Disease-2 | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Hereditary Spherocytosis | Snyder-Robinson Syndrome | Potocki-Shaffer Syndrome | Pyruvate Decarboxylase Deficiency | Basal Ganglia Disease | Arterial Tortuosity Syndrome | Delayed Sleep Phase Syndrome | Seminoma | Stromal Corneal Dystrophy | Congenital Poikiloderma | Hairy Cell Leukemia | Rolandic Epilepsy | Acanthosis Nigricans | Metachromatic Leukodystrophy | Cartilage Disorders | H Syndrome | Dysferlinopathy | Analgesia | Recurrent Respiratory Papillomatosis | Hypersensitivity Pneumonitis | Pulmonary Vein Stenosis | Leishmaniasis, Visceral | Genee-Wiedemann Syndrome | Familial Retinal Arterial Macroaneurysm | Skin Papilloma | DiGeorge Syndrome | Angiomyolipoma | Cornelia De Lange Syndrome | Borderline Personality Disorder | Posterior Polar Cataract | Hyperbilirubinemia | Atrial Septal Defect | Headache | Isobutyryl-CoA Dehydrogenase Deficiency | Rothmund-Thomson Syndrome | Isovaleric Acidemia | Craniosynostosis | Adenoma, Pleomorphic | Syndactyly | Agoraphobia | Basal Cell Nevus Syndrome | Hypotonia-cystinuria Syndrome | Lafora Disease | Galactosialidosis | Sleep Disorder | Lattice Corneal Dystrophy | Neurodevelopmental Disorders | Metaphyseal Chondrodysplasia, Schmid Type | Epidermolytic Hyperkeratosis | Guillain-Barre Syndrome | Osteogenesis Imperfecta | Sialoadenitis | Porencephaly | Diffuse Intrinsic Pontine Glioma | Gitelman Syndrome | Spinocerebellar Ataxia Type 17 | Meniere's Disease | Hepatitis, Autoimmune | Hemolytic Anemia | Renal Tubular Acidosis | Melanoma, Malignant | Thromboembolism | Hyperuricemia | Dementia, Vascular | Blastoma, Pleuropulmonary | Charcot-Marie-Tooth Disease Type 2T | Thrombasthenia | Non-proliferative Diabetic Retinopathy | Retinal Telangiectasia | Glycogen Storage Disease Type 3 | Familial Exudative Vitreoretinopathy | Antiphospholipid Syndrome | Hereditary Multiple Exostoses | Constipation | Rhabdoid Tumor | Retinopathy Of Prematurity | Generalized Epilepsy And Paroxysmal Dyskinesia | Gastritis | Generalized Epilepsy With Febrile Seizures Plus | Persistent Truncus Arteriosus | Patent Foramen Ovale | Warsaw Breakage Syndrome | Endocarditis | Spinocerebellar Ataxia Type 10 | Hemorrhage | Dysmorphophobia | Dyggve-Melchior-Clausen Disease | Acute Lung Injury | Familial Thoracic Aortic Aneurysm | Clouston Hidrotic Ectodermal Dysplasia | Encephalopathy, Ethylmalonic | Dysfibrinogenemia | Bruck Syndrome | Subacute Sclerosing Panencephalitis | Anosmia, Congenital | Poikiloderma With Neutropenia | Sialidosis Type I | Keratoacanthoma | Dent Disease | Hyperostosis | Rift Valley Fever | Hidradenitis | Aldosterone Synthase Deficiency | Glutaric Aciduria Type 1 | Narcolepsy | Retinal Vasculitis | Dermatitis | Congestive Heart Failure | Nephroblastoma | Dysthymia | Fibromyalgia | Scapuloperoneal Spinal Muscular Atrophy | Bethlem Myopathy | Juvenile Polyposis | Autoimmune Hemolytic Anemia | Asplenia | Gastrointestinal Disorders | Osteogenesis Imperfecta Type II | Progressive Myoclonic Epilepsy | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Rett Syndrome | Renal Medullary Carcinoma | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Spinocerebellar Ataxia Type 28 | Eating Disorder | FG Syndrome | Prolactinoma | Nephronophthisis | Osteonecrosis Of The Jaw | Blepharospasm | DRESS Syndrome | Encephalitis, Tick-borne | Cellulitis | Hydrocephalus | Neurofibroma, Plexiform | Thyroiditis, Autoimmune | Autoimmune Disease | Uveitis | Microphthalmia | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Hypotrichosis Simplex | Neutrophilia | Corneal Neovascularization | Tyrosinemia | Distal Myopathy | Leber Hereditary Optic Neuropathy | Hypophosphatasia | Primary Hyperoxaluria Type 1 | Inborn Errors Of Metabolism | Spasticity | Osteitis | VEXAS Syndrome | Lymphoma, Follicular | Gigantism | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Alagille Syndrome | Crouzon Syndrome With Acanthosis Nigricans | Hereditary Sensory And Autonomic Neuropathy | Pemphigus Vulgaris | Papulopustular Rosacea | Epilepsy | Ophthalmia, Sympathetic | Myoclonus-dystonia Syndrome | Osteoporosis | Discoid Lupus Erythematosus | Osmotic Demyelination Syndrome | Dystonia Musculorum Deformans | Autosomal Recessive Spastic Paraplegia Type 54 | Corticobasal Syndrome | Poirier-Bienvenu Neurodevelopmental Syndrome | Erythema Multiforme | Silicosis | Usher Syndrome | Hermansky-Pudlak Syndrome | Cardiofaciocutaneous Syndrome | Hypertension | Cherubism | Hypercholesterolemia, Familial | Multiple Epiphyseal Dysplasia | Obsessive-compulsive Disorder | Situs Inversus | Mixed Connective Tissue Disease | Kidney Stones | Congenital Stromal Corneal Dystrophy | Hypoplastic Left Heart Syndrome | Spinocerebellar Ataxia Type 1 | Synovitis | Chronic Periodontitis | 3-methylglutaconic Aciduria | Hemangioma | 5-oxoprolinase Deficiency | Pouchitis | Ischemia | Intermittent Explosive Disorder | Hemosiderosis | Diarrhea | Neuromyelitis Optica | Fragile X Syndrome | Huntington's Disease | Nicotine Addiction | Hartsfield Syndrome | Spondylolisthesis | Hennekam Lymphangiectasia-lymphedema Syndrome | Pseudohypoparathyroidism Type 2 | Lymphoproliferative Disorders | GAPO Syndrome | Glaucoma, Congenital | Personality Disorders | Acute Tubular Necrosis | Inflammatory Linear Verrucous Epidermal Nevus | Malignant Peripheral Nerve Sheath Tumor | Polycystic Liver | Spinocerebellar Ataxia Type 7 | C3 Glomerulonephritis | Charcot-Marie-Tooth Disease Type 2D | Cutaneous Angiosarcoma | Colitis, Microscopic | Ocular Albinism Type 1 | Stargardt Disease | Heterotaxy | Sarcomatoid Carcinoma Of The Lung | Seizures | Pontocerebellar Hypoplasia | Intestinal Pseudo-obstruction | Meconium Ileus | Pure Autonomic Failure | Anorectal Fistula | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Hamartoma | Rotor Syndrome | Chorioretinitis