Nicotine Addiction

About the Disease
Tobacco Addiction, also known as nicotine dependence, is related to alcohol dependence and major depressive disorder. An important gene associated with Tobacco Addiction is SLC6A3 (Solute Carrier Family 6 Member 3), and among its related pathways/superpathways are Metabolism and Nanog in Mammalian ESC Pluripotency. The drugs Naltrexone and Oxytocin have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and prefrontal cortex, and related phenotypes are homeostasis/metabolism and nervous system

Common Targets
CHN2 | CYP1A1 | CYP2A6 | G7157 | SLC6A4 | CHRNA7 | NEDD4L | OR12D3 | HCRTR1 | Nicotinic alpha4beta2 receptor | Nicotinic alpha3beta4 Receptor | MAL | SV2C | HIC1 | HCRTR2 | CHRNA3 | BDNF-AS | G1029 | OPRM1 | LRRN3 | CHAT | CYP2B6 | HECTD2-AS1 | GNG12 | F2RL3 | CHRM2 | DRD2 | CHRNA4 | CHRNB2 | alpha-6 beta-2 Nicotinic receptor | OPRK1 | BDNF | G3569 | CNR1 | PTPN6 | COMT | EGLN2 | CHRNA5 | RAB4B | AHRR | CPOX | CHRNB3

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