Disease

Otosclerosis

About the Disease
Otosclerosis, also known as otospongiosis, is related to bone resorption disease and ankylosis, and has symptoms including earache An important gene associated with Otosclerosis is OTSC2 (Otosclerosis 2), and among its related pathways/superpathways are Phospholipase-C Pathway and Extracellular matrix organization. The drugs Acetylcysteine and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include bone, adrenal cortex and cortex, and related phenotypes are limbs/digits/tail and digestive/alimentary

Common Targets
COL1A1 | BMP4 | PPP2R5B | BMP2 | MMP2 | MEPE | TGFB1 | FOXL1 | FGF2 | RELN | Parathyroid Hormone Receptors (PTHR) (nonspecified subtype) | SERPINF1

疾病靶点研报
Otosclerosis

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