Disease

Spinocerebellar Ataxia Type 12

About the Disease
Spinocerebellar Ataxia 12, also known as spinocerebellar ataxia type 12, is related to spinocerebellar ataxia 36 and multiple system atrophy 1, and has symptoms including dysdiadochokinesis and head tremor. An important gene associated with Spinocerebellar Ataxia 12 is PPP2R2B (Protein Phosphatase 2 Regulatory Subunit Bbeta), and among its related pathways/superpathways are Akt Signaling and Dopamine-DARPP32 Feedback onto cAMP Pathway. Affiliated tissues include spinal cord, cerebellum and eye, and related phenotypes are hyperreflexia and cerebellar atrophy

Common Targets
PPP2R2B

疾病靶点研报
Spinocerebellar Ataxia Type 12

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