Noonan Syndrome-like Disorder With Loose Anagen Hair

About the Disease
Noonan Syndrome-Like Disorder with Loose Anagen Hair 1, also known as mazzanti syndrome, is related to noonan syndrome-like disorder with loose anagen hair and exanthem. An important gene associated with Noonan Syndrome-Like Disorder with Loose Anagen Hair 1 is SHOC2 (SHOC2 Leucine Rich Repeat Scaffold Protein), and among its related pathways/superpathways are Disease and Signal Transduction. Affiliated tissues include skin and brain, and related phenotypes are deep palmar crease and hypoplasia of the corpus callosum

Common Targets
SHOC2 | PPP1CB | PTPN11

Note: If you'd like to get a target analysis report for Noonan Syndrome-like Disorder With Loose Anagen Hair, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Noonan Syndrome-like Disorder With Loose Anagen Hair at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Frontotemporal Dementia | Autoimmune Interstitial Lung, Joint, And Kidney Disease | NDH Syndrome | Familial Thoracic Aortic Aneurysm | Astigmatism | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Hemoglobinopathies | Hypertension, Renal | MELAS Syndrome | Glucagonoma | Graft-versus-host Disease | Beckwith-Wiedemann Syndrome | Oculocutaneous Albinism | Tardive Dyskinesia | Idiopathic Pulmonary Fibrosis | Hepatitis A | Hypersensitivity | Cerebellofaciodental Syndrome | Prediabetes | Spinal Cord Diseases | Scleroderma, Diffuse | Phosphoglycerate Dehydrogenase Deficiency | Maternally Inherited Diabetes And Deafness | C3 Glomerulonephritis | Spondylocostal Dysostosis | Hemochromatosis Type 2 | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Behavioral Variant Of Frontotemporal Dementia | Hereditary Multiple Exostoses | Myositis, Focal | Hyperparathyroidism-jaw Tumor Syndrome | Peritonitis | Neural Tube Defect | Charcot-Marie-Tooth Disease, Type 6 | Lymphomatoid Granulomatosis | Fucosidosis | McCune-Albright Syndrome | Macrophage Activation Syndrome | Meningioma | Arthropathy | Porokeratosis | Mesothelioma, Malignant | Sarcoma, Ewing | Ehlers-Danlos Syndrome | Acral Lentiginous Melanoma | Hypopituitarism | Acrocallosal Syndrome | Progressive Familial Intrahepatic Cholestasis Type 1 | Focal Cortical Dysplasia Type 2 | Fetal And Neonatal Alloimmune Thrombocytopenia | Familial Digital Arthropathy-brachydactyly | Trichuriasis | Mitochondrial DNA Depletion Syndrome 13 | Nager Acrofacial Dysostosis | Venous Insufficiency | Joubert Syndrome 2 | Vaginitis | Succinic Semialdehyde Dehydrogenase Deficiency | Spondylocarpotarsal Synostosis Syndrome | Thymoma, Malignant | Sickle Cell Disease | Riboflavin Transporter Deficiency Neuronopathy | Motion Sickness | HIBCH Deficiency | Leigh Syndrome | Asphyxia Neonatorum | Dysferlinopathy | Kashin-Beck Disease | Asthma, Exercise-induced | Carney Triad | Pontocerebellar Hypoplasia Type 2 | Metanephric Adenoma | Mabry Syndrome | Esophagitis, Eosinophilic | Marshall-Smith Syndrome | Methemoglobinemia | Tuberculous Meningitis | Tremor | Familial Hypertrophic Cardiomyopathy | Carpal Tunnel Syndrome | Gastritis | Retinitis Pigmentosa 3 | Hepatitis, Alcoholic | Nail Disorder, Nonsyndromic Congenital | Lipoma | Acrodysostosis | Neuropathy | Carcinoma, Squamous Cell | Arts Syndrome | Cervicitis | Pendred Syndrome | Hypogammaglobulinemia | Absence Epilepsy | Mucolipidosis Type III | Majeed Syndrome | Hyperbilirubinemia, Neonatal | Uveitis | Renal Hypouricemia | Tietze Syndrome | Endometrial Hyperplasia | Dyslipidemia | Leri Pleonosteosis | Osteopathia Striata With Cranial Sclerosis | Schistosomiasis | Retinal Diseases | Kallmann Syndrome | Portal Vein Thrombosis | Hepatitis, Chronic | Cavitary Optic Disc Anomalies | Pneumonia, Bacterial | Primary Cutaneous Amyloidosis | Congenital Hereditary Endothelial Dystrophy Type I | Retinal Detachment | Zygomycosis | Microphthalmia | Charcot-Marie-Tooth Disease Type 4D | Coronary Artery Disease | Holt-Oram Syndrome | Pure Red Cell Aplasia | Distal Spinal Muscular Atrophy | Corneal Dystrophies, Hereditary | Corneal Edema | Keratosis, Actinic | Glaucomatocyclitic Crisis | Cryptorchidism | Osteogenesis Imperfecta Type V | Pemphigus Foliaceus | Niemann-Pick Disease, Type C | Polycythemia Vera | Diabetes Mellitus, Transient Neonatal | Plasmacytoma | Walker-Warburg Syndrome | Keratoconjunctivitis | Atrioventricular Septal Defect | Conduct Disorder | Sick Sinus Syndrome 1 | Spinocerebellar Ataxia | Familial Glucocorticoid Deficiency | Pyruvate Carboxylase Deficiency Disease | Epidermolysis Bullosa Simplex | Malignant Peripheral Nerve Sheath Tumor | Temporal Lobe Epilepsy | Proteasome-associated Autoinflammatory Syndrome 2 | Adrenal Insufficiency | Chiari Malformation Type I | Cone Dystrophy | Canavan Disease | Dubin-Johnson Syndrome | Carotid Artery Disease | Constipation | Bacterial Meningitis | Hereditary Neuropathy With Liability To Pressure Palsies | Neurocysticercosis | Axenfeld-Rieger Syndrome | Gitelman Syndrome | Pseudohypoparathyroidism Type 1B | CEDNIK Syndrome | Spinocerebellar Ataxia Type 7 | Necrotizing Autoimmune Myopathy | Paroxysmal Kinesigenic Dyskinesia | Hereditary Hemorrhagic Telangiectasia Type 2 | Presbyopia | Hypogonadism | Waardenburg Syndrome Type 1 | Cohen Syndrome | Localized Scleroderma | Crohn's Disease | Pompe Disease | Congenital Tufting Enteropathy | Pseudoexfoliation Syndrome | Angioedema, Acquired | Eczema | Charcot-Marie-Tooth Disease Type 4 | Hereditary Spastic Paraplegia | Otopalatodigital Syndrome Type 2 | Martsolf Syndrome | Batten Disease | Autosomal Recessive Bestrophinopathy | Multiple Sclerosis | Aneurysm, Thoracic Aortic | Ataxia-ocular Apraxia 2 | Hypercalciuria | Proctitis | Hereditary Elliptocytosis | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Primary Carnitine Deficiency | Traboulsi Syndrome | Chronic Kidney Disease | Craniopharyngioma | Bietti Crystalline Dystrophy | Leukemia | Thyroiditis | Hypercalcemia | Alpha-mannosidosis | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Blue Nevus | Melanoma, Malignant | CHOPS Syndrome | Hypophosphatasia | Hypertension, Pulmonary | Trichomegaly | Spinal Muscular Atrophy Type 3 | Schizophrenia | Reticular Dysgenesis | Cervical Dystonia | Preaxial Polydactyly | Filariasis | Multiple Hamartoma Syndrome | Peeling Skin Syndrome, Acral Type | Nail-Patella Syndrome | Hereditary Inclusion Body Myopathy | Congenital Hypofibrinogenemia | Pseudohypoparathyroidism Type 1C | Glycogen Storage Disease Type 1 | VACTERL/VATER Association | Osteonecrosis | Rothmund-Thomson Syndrome | Beare-Stevenson Syndrome | Pulmonary Alveolar Microlithiasis | Vertigo | Seizures-scoliosis-macrocephaly Syndrome | Gestational Trophoblastic Disease | Acromicric Dysplasia | Otitis Media | Cleidocranial Dysplasia | Autonomic Neuropathy | Erythematotelangiectatic Rosacea | Scapuloperoneal Spinal Muscular Atrophy | T-cell Chronic Lymphocytic Leukemia | Acute Chest Syndrome | Chronic Thromboembolic Pulmonary Hypertension | Epidermolysis Bullosa Simplex, Localized | Arthritis, Gouty | Schwartz-Jampel-Aberfeld Syndrome | Aldosterone Deficiency | Psoriasis | Farber Disease | Hydrocephalus, Normal Pressure | Orotic Aciduria | Retinopathy Of Prematurity | Split Hand-foot Malformation | Chromosome 17q21.31 Deletion Syndrome | Congenital Adrenal Hyperplasia 1 | Vitamin B12 Deficiency | Hepatitis | Lymphoma, Follicular | Spinocerebellar Ataxia Type 40 | Chronic Mucocutaneous Candidiasis | Hepatorenal Syndrome | Sjogren Syndrome | Trachoma | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Meningeal Melanocytoma | Neuromuscular Disorders | Neurofibrosarcoma | Persistent Hyperplastic Primary Vitreous | Papillon-Lefevre Syndrome | Hidradenitis Suppurativa | Azoospermia | Dysfibrinogenemia | Focal Segmental Glomerulosclerosis | Yellow Fever | Protein S Deficiency | Sarcoma | Alstrom Syndrome | Rotor Syndrome | Thrombocythemia, Essential | Adenocarcinoma | Monilethrix | Glycogen Storage Disease Type 9 | DRESS Syndrome | Granuloma Annulare | Nephronophthisis | Galloway-Mowat Syndrome | Retinal Coloboma | Bone Marrow Necrosis | Basal Ganglia Disease, Biotin-responsive | Kidney Stones | Neurofibroma | T-cell Prolymphocytic Leukemia | Adenomyosis | Metachondromatosis | Multiple Sclerosis, Secondary Progressive | Vitreoretinal Degeneration, Snowflake Type | Hepatic Adenomatosis | Triphalangeal Thumb-polysyndactyly Syndrome | Aromatic L-amino Acid Decarboxylase Deficiency | Amelanotic Melanoma | Cystitis | Varicocele | Non-Hodgkin Lymphoma | Primary Progressive Aphasia | Pseudohypoparathyroidism Type 1A | Bainbridge-Ropers Syndrome | Angiosarcoma Of The Breast | Oculocutaneous Albinism Type 2 | Chronic Enteropathy Associated With SLCO2A1 Gene | Ophthalmoplegia | POEMS Syndrome | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Mumps | Pleurisy | Lactose Intolerance | Benign Familial Pemphigus | Ureteropelvic Junction Obstruction | Basal Cell Nevus Syndrome | Lateral Meningocele Syndrome | Cardiomyopathy, Hypertrophic | GM2-gangliosidosis AB Variant | Sarcoma, Alveolar Soft Part | Pearson Syndrome | T-cell Lymphoma, Subcutaneous Panniculitis-like | Gardner Syndrome | Fetal Alcohol Syndrome | Empyema | Hypospadias | Kindler Syndrome | Rheumatic Heart Disease | Peters-plus Syndrome | Abetalipoproteinemia | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Hyper IgE Syndrome | Leukoplakia | Von Hippel-Lindau Disease | Cutis Laxa | Osteoarthritis | Hyperinsulinemia | Thyrotoxic Periodic Paralysis | HANAC Syndrome | Congenital Stationary Night Blindness | Wolfram Syndrome 2 | Systemic Lupus Erythematosus | Primary Pigmented Nodular Adrenocortical Disease | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Stromal Corneal Dystrophy | Castleman Disease | Alopecia Areata | Ameloblastoma | Esophagitis | Microvillus Inclusion Disease | Olmsted Syndrome | Fanconi Syndrome | DiGeorge Syndrome | Spinocerebellar Ataxia Type 3 | Otitis Externa | Odonto-onycho-dermal Dysplasia | Cri-du-chat Syndrome | Heimler Syndrome | Cyst | Alexander Disease | Hepatoblastoma | Motor Neuron Diseases | Dermatitis | Proximal Symphalangism | Membranous Nephropathy | Von Willebrand Disease | Necrobiosis Lipoidica | Infertility | Polycystic Kidney, Autosomal Recessive | Chordoma | Nephroblastoma | Cryopyrin-associated Periodic Syndromes | Trismus-pseudocamptodactyly Syndrome | Pre-eclampsia | Scapuloperoneal Myopathy, X-linked Dominant | Pituitary Dwarfism | Roberts Syndrome | Hyperinsulinism-hyperammonemia Syndrome | Androgenic Alopecia | Primary Erythromelalgia | Ocular Albinism Type 1 | Blomstrand Osteochondrodysplasia | Patent Ductus Arteriosus | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Acanthosis Nigricans | Joubert Syndrome | Lipid Metabolism Disorders | Spermatocele | Bulimia Nervosa | Multiple Epiphyseal Dysplasia | Aspartylglycosaminuria | Ganglioglioma | Dent Disease | Lamellar Ichthyosis | Microtia | Nicotine Dependence | N-acetylglutamate Synthase Deficiency | Pancreatitis | Systemic Mastocytosis | Osmotic Demyelination Syndrome | Osteonecrosis Of The Jaw | Blepharoconjunctivitis | Kearns-Sayre Syndrome | Retinitis Pigmentosa | Hamartoma | Cheilitis | Smith-Lemli-Opitz Syndrome | Familial Isolated Hyperparathyroidism | Werner's Syndrome | Bronchitis