Adenomyosis

About the Disease
Adenomyosis, also known as endometriosis of uterus, is related to leiomyoma and adenomyoma. An important gene associated with Adenomyosis is ESR1 (Estrogen Receptor 1), and among its related pathways/superpathways are ERK Signaling and GPCR Pathway. The drugs Oxytocin and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include uterus, ovary and neutrophil, and related phenotypes are abnormal bleeding and dysmenorrhea

Common Targets
RHOJ | TMEM132C | MED13 | LMF1 | NR3C1 | PADI2 | PIK3CA | PMVK | PPM1F | ABHD8 | RRAGA | PGR | ITGA2 | SCN3A | GLYATL3 | HIPK1 | PGS1 | PPP2R1A | OSGIN1 | NLRP5 | CUZD1 | MKNK1 | ABCG1 | KIF4A | RAB40B | G367 | NHS | ZNF445 | OXT | G3845 | KIAA1671 | MYADML2 | TTC21A | SH3BP4 | LSP1 | ZNF207 | SMPDL3B | GPR27 | RBBP8 | ST6GAL2 | ZNG1C | AJAP1 | KMT2D | ATP13A4 | ZNF512B | UNC5A | TSPYL2 | SNAPC1 | C1QTNF6 | ZNF565 | OXTR | MMP1 | ARHGAP42 | PRKACA | FER1L6 | UTP14A | PLXNB3 | HIF1A | OR51D1 | C12orf42 | LIPG | CCDC168 | NBPF10 | NPAP1 | ZNF468 | CR2 | GNA12 | OR5M10 | KIAA1755 | RAET1G | MXRA5

Note: If you'd like to get a target analysis report for Adenomyosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Adenomyosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Inflammatory Myopathy | Colitis, Collagenous | Sponastrime Dysplasia | Periodic Limb Movement Disorder | Focal Facial Dermal Dysplasia | Multisystemic Smooth Muscle Dysfunction Syndrome | Polycythemia | Hepatoblastoma | Hyperprolactinemia | Amyotrophic Lateral Sclerosis | Spinocerebellar Ataxia Type 2 | Niemann-Pick Disease, Type C | Cerebral Cavernous Malformations | Bone Giant Cell Tumor | Early Infantile Epileptic Encephalopathy 1 | Urticaria | Leishmaniasis, Cutaneous | Fraser Syndrome | Usher Syndrome | Hepatitis C, Chronic | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Globozoospermia | Schwannomatosis | Eiken Syndrome | Camptocormia | Nevus | Esophageal Adenocarcinoma | Tonsillitis | Thrombocythemia, Essential | Myeloid Leukemia | Pseudohypoparathyroidism Type 2 | Sleep Disorder | Oligoasthenoteratozoospermia | Bietti Crystalline Dystrophy | Multiple Sclerosis, Secondary Progressive | Spinocerebellar Ataxia Type 6 | Zygomycosis | Autoimmune Disease | Primrose Syndrome | Acanthosis Nigricans | Familial Mediterranean Fever | Leukemia | Primary Cutaneous Amyloidosis | Dysplastic Nevus | Pulmonary Tuberculosis | Trichomegaly | Hypoplastic Left Heart Syndrome | Hyperthyroidism | Restrictive Dermopathy | Speech Disorders | Pleural Tuberculosis | Fanconi Syndrome | Abetalipoproteinemia | Irritable Bowel Syndrome | Infantile Nephropathic Cystinosis | Sclerosteosis 2 | Urethritis | Bardet-Biedl Syndrome | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Spinocerebellar Ataxia Type 1 | Vascular Calcification | Autoimmune Autonomic Ganglionopathy | Myoclonic Atonic Epilepsy | Dementia | Cold Agglutinin Disease | Lymphoma, Follicular | Brachydactyly | Myasthenia | Behcet's Disease | Anuria | Heavy Chain Disease | Cystitis | Sarcoma, Alveolar Soft Part | Liver Failure, Acute Infantile | Adenoma, Villous | Osteochondroma | Congenital Bilateral Absence Of Vas Deferens | Guanidinoacetate Methyltransferase Deficiency | Acute Leukemia | Epidermolysis Bullosa Dystrophica | Hypertension | Axenfeld-Rieger Syndrome | B-cell Chronic Lymphocytic Leukemia | Hypercalcemia | Common Cold | Pendred Syndrome | Glycogen Storage Disease Type 9 | Greenberg Dysplasia | Osteitis | Early Infantile Epileptic Encephalopathy 28 | Lymphomatoid Granulomatosis | Gingivitis | Adenosine Deaminase Deficiency | Meningitis | Hyperparathyroidism | Twin-to-twin Transfusion Syndrome | Blepharoconjunctivitis | Exostoses | Amyloidosis | Alpha-thalassemia Myelodysplasia Syndrome | Nemaline Myopathy 8 | Ollier Disease | Glycogen Storage Disease Type 1a | Pontocerebellar Hypoplasia Type 2 | Carney-Stratakis Syndrome | H Syndrome | Loeys-Dietz Syndrome Type 4 | Oligoastrocytoma | Liddle Syndrome | Cavitary Optic Disc Anomalies | Cramp Fasciculation Syndrome | Moyamoya Disease | Erdheim-Chester Disease | Primary Aldosteronism | Glaucoma, Congenital | Carney Triad | Rolandic Epilepsy | Sertoli Cell-only Syndrome | Alkaptonuria | Acne Vulgaris | Whipple's Disease | Pseudoexfoliation Syndrome | Pneumococcal Meningitis | Acute Myeloid Leukemia | Apert Syndrome | Papillon-Lefevre Syndrome | Pain | Coenzyme Q10 Deficiency | Sitosterolemia | Hypotrichosis Simplex | Chronic Granulomatous Disease | Spasticity | Duodenal Atresia | Dysthymia | Pineoblastoma | Spondylometaphyseal Dysplasia | Connective Tissue Disorders | Retinal Telangiectasia | Cole-Carpenter Syndrome | Kallmann Syndrome | B-cell Prolymphocytic Leukemia | Focal Segmental Glomerulosclerosis | Lipid Storage Myopathy | Cysticercosis | Myoclonic Epilepsy With Ragged Red Fibers | Carcinoid Syndrome | Early Infantile Epileptic Encephalopathy 13 | Fontaine Progeroid Syndrome | Osteogenesis Imperfecta Type I | Atherosclerosis | Meleda Disease | Cancer, Brain | AIDS | Wilson's Disease | Batten Disease | Hemochromatosis | Hyperphenylalaninemia | Menkes Disease | Stiff-man Syndrome | Zimmermann-Laband Syndrome | Spinocerebellar Ataxia Type 28 | Asphyxia Neonatorum | Hemorrhage | Non-proliferative Diabetic Retinopathy | Hyperparathyroidism-jaw Tumor Syndrome | Necrotizing Autoimmune Myopathy | Burn-McKeown Syndrome | Nestor-Guillermo Progeria Syndrome | Intermittent Explosive Disorder | Arteriosclerosis | Spinocerebellar Ataxia Type 42 | Craniometaphyseal Dysplasia | Trismus-pseudocamptodactyly Syndrome | Venous Insufficiency | Osteomalacia | Juvenile Myoclonic Epilepsy | Hemochromatosis Type 2 | Colitis, Lymphocytic | Haim-Munk Syndrome | Stuttering | Porphyria, Variegate | Carcinoma, Squamous Cell | Hyperandrogenemia | Neurodevelopmental Disorders | Benign Familial Neonatal Convulsions | Leiomyoma | Prolactinoma | Congestive Heart Failure | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Arthritis, Psoriatic | Cardiac Arrest | Gliosarcoma | Neurofibrosarcoma | Specific Granule Deficiency | Antisocial Personality Disorder | Pilomatrix Carcinoma | Yellow Fever | Pantothenate Kinase-associated Neurodegeneration | Congenital Myopathy | Sarcoma, Endometrial Stromal | Panic Disorder | Inflammatory Joint Disease | Vitreoretinopathy, Proliferative | Urea Cycle Disorder | Early Infantile Epileptic Encephalopathy | Hypertension, Renal | Motor Neuron Diseases | HANAC Syndrome | Sleep Apnea | Schindler Disease | Arterial Tortuosity Syndrome | Anorectal Malformations | Hypotension, Orthostatic | Encephalopathy, Glycine | Skin Papilloma | Hypothalamic Obesity | Diffuse Palmoplantar Keratoderma | Tardive Dyskinesia | Niemann-Pick Disease | Omenn Syndrome | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | REM Sleep Behavior Disorder | Juvenile Xanthogranuloma | Hypersensitivity | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Chorioretinitis | Cardiomyopathy, Hypertrophic | Bronchiectasis | Tuberculous Meningitis | Corneal Dystrophies, Hereditary | Larsen Syndrome | Hereditary Sensory Neuropathy Type 1 | Bartter Syndrome | Evans Syndrome | Choroideremia | Coronary Heart Disease | Best Macular Dystrophy | Thyroid Hormone Resistance | Adrenomyeloneuropathy | Distal Myopathy | Hyperacusis | Sulfite Oxidase Deficiency | Lennox-Gastaut Syndrome | GAPO Syndrome | Pyruvate Decarboxylase Deficiency | Keratitis-ichthyosis-deafness Syndrome | Craniofacial Dysostosis | Nephrotic Syndrome Type 1 | Carpenter Syndrome | Schizencephaly | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Persistent Fetal Circulation | Hyperinsulinemic Hypoglycemia | Dystonia-parkinsonism, X-linked | Uterine Leiomyoma | Pompe Disease | Porphyria Cutanea Tarda | Depression | Cardiomyopathy, Restrictive | Microphthalmia | Klippel-Feil Syndrome | Gallstones | Spinocerebellar Ataxia Type 16 | Congenital Disorders Of Glycosylation | LEOPARD Syndrome | Mucolipidosis | Heart Septal Defects | FG Syndrome | Dengue Shock Syndrome | Enlarged Vestibular Aqueduct | Scleritis | Gastroenteritis | Heterotopic Ossification | Leukocyte Adhesion Deficiency | Epidermolysis Bullosa Simplex, Generalized | Thanatophoric Dysplasia Type 1 | Noonan Syndrome-like Disorder With Loose Anagen Hair | Neurocutaneous Syndromes | IgA Nephropathy | Fibrodysplasia Ossificans Progressiva | Corticobasal Syndrome | Hydrocephalus | Basal Ganglia Disease, Biotin-responsive | VEXAS Syndrome | Neurocysticercosis | Congenital Stationary Night Blindness | Glanzmann Thrombasthenia | Pleurisy | Waardenburg Syndrome Type 1 | Epilepsy Of Infancy With Migrating Focal Seizures | Retinopathy Of Prematurity | Hypertelorism | Muscular Dystrophy | 3-methylglutaconic Aciduria Type IV | Saethre-Chotzen Syndrome | Eccrine Porocarcinoma | Nail-Patella Syndrome | Methemoglobinemia Type IV | Retinoblastoma | DiGeorge Syndrome | Erythema Nodosum | Congenital Dyserythropoietic Anemia Type 4 | Hereditary Xerocytosis | Hyper IgE Syndrome | Tibial Muscular Dystrophy | Iron Overload | Progressive Myoclonic Epilepsy | Urofacial Syndrome | Albinism | Tyrosine Hydroxylase Deficiency | Orthostatic Intolerance | Papilledema | Schwannoma | Spinocerebellar Ataxia Type 10 | Coronary Artery Disease | Renal Medullary Carcinoma | Mosaic Variegated Aneuploidy Syndrome 2 | Neurofibromatosis-Noonan Syndrome | Usher Syndrome Type III | Heterotaxy | Teratozoospermia | Schizotypal Personality Disorder | Coma | Acute Lung Injury | KBG Syndrome | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Oculocutaneous Albinism Type 2 | Eclampsia | Centronuclear Myopathy | Cold-induced Sweating Syndrome | Atelosteogenesis Type 1 | Leishmaniasis, Visceral | Hypermetropia | Sjogren Syndrome | Varices | Weill-Marchesani Syndrome | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Stroke, Hemorrhagic | Acute Anterior Uveitis | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Raine Syndrome | Salla Disease | Rhabdomyosarcoma, Embryonal | Hyperparathyroidism, Secondary | Tinea Versicolor | WAGR Syndrome | Nephrosclerosis | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Riboflavin Transporter Deficiency Neuronopathy | Congenital Torticollis | Endophthalmitis | Epilepsy | Guillain-Barre Syndrome | Schistosomiasis | Photosensitivity | Paraganglioma | Sporadic Hemiplegic Migraine | Varicocele | Blepharophimosis Syndrome | Hydrolethalus Syndrome | Neuroblastoma | Aplastic Anemia | Encephalopathy, Ethylmalonic | Chediak-Higashi Syndrome | Angelman Syndrome | Protein C Deficiency | Hepatic Adenomatosis | Charcot-Marie-Tooth Disease Type 2E | Encephalopathy | Chordoid Glioma | Primary Progressive Nonfluent Aphasia | Osteopetrosis | Dysequilibrium Syndrome | Keratoconus | Trimethylaminuria | Anxiety Disorders | Unverricht-Lundborg Syndrome | ICF Syndrome | Pyoderma Gangrenosum | GATA2 Deficiency | Neurocutaneous Melanocytosis | Cutaneous Lupus Erythematosus | Palmoplantar Keratoderma | Ganglioglioma | Cholangiocarcinoma | Proopiomelanocortin Deficiency | Rhizomelic Chondrodysplasia Punctata | Acrodermatitis Enteropathica | Arts Syndrome | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Fibronectin Glomerulopathy | Esophageal Motility Disorders | Erythrokeratodermia Variabilis | Exfoliative Dermatitis | Stroke | N-acetylglutamate Synthase Deficiency | Hypotrichosis | Leber Congenital Amaurosis | Uremic Pruritus | Acrodysostosis