Keratopathy

About the Disease
Keratopathy is related to punctate epithelial keratoconjunctivitis and lagophthalmos. An important gene associated with Keratopathy is NLRP1 (NLR Family Pyrin Domain Containing 1), and among its related pathways/superpathways are ERK Signaling and Phospholipase-C Pathway. The drugs Mycophenolic acid and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include endothelial, eye and thyroid, and related phenotypes are no effect and no effect

Common Targets
HLA-B | Nicotinic alpha3beta4 Receptor | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | CHRNA7 | Nicotinic alpha4beta2 receptor | FASLG | HLA-DRB3 | PDCD1LG2 | FAS | alpha-6 beta-2 Nicotinic receptor | CHRNB2 | G5133

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