Postpoliomyelitis Syndrome

About the Disease
Postpoliomyelitis Syndrome, also known as postpolio syndrome, is related to progressive muscular atrophy and sleep apnea. An important gene associated with Postpoliomyelitis Syndrome is C17orf80 (Chromosome 17 Open Reading Frame 80), and among its related pathways/superpathways are "Oligodendrocyte specification and differentiation, leading to myelin components for CNS" and Interactions of natural killer cells in pancreatic cancer. The drugs Modafinil and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, skeletal muscle and lung, and related phenotypes are muscle weakness and fatigue

Common Targets
CLCN1

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