Dystonia

About the Disease
Dystonia, also known as dystonic disorder, is related to dystonia 12 and dystonia, dopa-responsive, and has symptoms including back pain, headache and muscle cramp. An important gene associated with Dystonia is ATP1A3 (ATPase Na+/K+ Transporting Subunit Alpha 3), and among its related pathways/superpathways are Autophagy and Alpha-synuclein signaling. The drugs Levodopa and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include globus pallidus, brain and subthalamic nucleus, and related phenotypes are no effect and no effect

Common Targets
TUBB4A | SPG11 | PDE8A | NOS3 | ARSG | GCH1 | GNAL | ATXN8OS | TRNS2 | NUP54 | RGS10 | PDE10A | SPR | GNAO1 | NKX2-1 | TAF1 | PRKCG | TSPOAP1 | ATP13A2 | HTR2A | DBH | MCOLN1 | VPS16 | PRRT2 | MECP2 | PTS | SUOX | EIF2AK2 | VPS11 | ARX | PPP1R1B | KMT2B | AGTR1 | TIMM8A | POLG | DRD1 | G472 | ANO3 | CIZ1 | SUCLG1 | COQ8A | HPCA | MRE11 | ADCY5 | HIBCH | KMT2D | SLC39A14 | PINK1 | IMPDH2 | ATP5MC3 | KIF1C | CLCN2 | ATP1A3 | SLC2A1 | SLC6A3 | GPR55 | TH | SYNE1 | DCTN1 | COX20 | KCNMA1 | NT5E | SLC6A1 | AOPEP | SLC5A7 | ACE | Soluble guanylyl cyclase | SETX | CNBD1 | PRKRA | THAP1 | CNR2 | TPI1 | XK | SGCE | JPH1 | PANK2 | COL6A3 | CACNB4 | CHRNA6 | BDNF | NUP62 | LRRK2 | COMT | CNR1 | ABCD1 | CP | KCNN2 | PDE7A | TOR1A | NOP56 | CNTNAP1 | ACHE | CACNA1B | ATL1 | SV2A | DDC | RAB29 | HNRNPU antisense RNA 1 | ACTB | DNAJC13 | GRM5 | C19orf12 | SLC39A8 | SLC18A2 | SHQ1 | GBA1 | RNF13 | CHRM4 | ECHS1 | CHRM1

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