Disease

Tumoral Calcinosis

About the Disease
Tumoral Calcinosis, Hyperphosphatemic, Familial, 1, also known as hyperphosphatemic familial tumoral calcinosis, is related to hyperostosis and hypercalcemia, infantile, 1. An important gene associated with Tumoral Calcinosis, Hyperphosphatemic, Familial, 1 is GALNT3 (Polypeptide N-Acetylgalactosaminyltransferase 3), and among its related pathways/superpathways are Disease and Signaling by Receptor Tyrosine Kinases. The drugs Salmon calcitonin and Calcitonin gene-related peptide have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and eye, and related phenotypes are bone pain and periarticular subcutaneous nodules

Common Targets
ATP8A2 | LIAS | GALNT3 | ACSF2 | DNAH2 | FGF23 | HGS | DNAH17 | FBXO38 | CDH19 | SDK2 | GRK5 | KL | COX8C | TFF2 | ANXA2 | OR1J4

疾病靶点研报
Tumoral Calcinosis

Note: If you'd like to get a target analysis report for Tumoral Calcinosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Tumoral Calcinosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

VACTERL Association | Epidermolysis Bullosa Simplex, Generalized | Asthma, Exercise-induced | Hereditary Mixed Polyposis Syndrome | Dementia | Pyruvate Dehydrogenase Deficiency | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Macrophage Activation Syndrome | Schuurs-Hoeijmakers Syndrome | Hyperinsulinism-hyperammonemia Syndrome | Cryptosporidiosis | Rolandic Epilepsy | Branchiootorenal Syndrome | Bernard-Soulier Syndrome | Asperger Syndrome | Evans Syndrome | Microcephaly | Pleomorphic Xanthoastrocytoma | Proteasome-associated Autoinflammatory Syndrome 2 | Acute Lung Injury | Hypercholesterolemia, Familial | Pulverulent Zonular Cataract | Renal Hypouricemia | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Lipodystrophy | Vaginitis | Alopecia | Nasodigitoacoustic Syndrome | Pontocerebellar Hypoplasia Type 2 | Oculocutaneous Albinism Type 2 | Focal Dermal Hypoplasia | Spinocerebellar Ataxia Type 10 | Hypertensive Retinopathy | Hypobetalipoproteinemias | Endophthalmitis | Systemic Mastocytosis | Multifocal Motor Neuropathy | Hepatic Adenomatosis | Familial Partial Lipodystrophy | Joubert Syndrome | Diverticulitis | Takayasu's Arteritis | Constipation | Varices | Ocular Hypertension | Adenoma, Villous | Primary Aldosteronism | Cystinosis | Amish Infantile Epilepsy Syndrome | Huntington's Disease-like 2 | Esophageal Adenocarcinoma | Schizophrenia, Paranoid | Acne Vulgaris | Primary Ovarian Insufficiency | Hoyeraal-Hreidarsson Syndrome | Hypertension, Pulmonary | Major Depression | Calcium Pyrophosphate Deposition Disease | Myelitis | Facioscapulohumeral Muscular Dystrophy Type 2 | Oculodentodigital Dysplasia | Early Infantile Epileptic Encephalopathy 4 | Spastic Paraplegia Type 7 | Retinoschisis | Sarcoidosis, Pulmonary | Vici Syndrome | Postpoliomyelitis Syndrome | Nemaline Myopathy 8 | HELLP Syndrome | Hypermethioninemia | Lymphoma, AIDS-related | Mitochondrial DNA Depletion Syndrome | Sialidosis Type I | Sulfite Oxidase Deficiency | Vulvovaginitis | Nemaline Myopathy | Portal Vein Thrombosis | Familial Glucocorticoid Deficiency | Diffuse Palmoplantar Keratoderma | Birt-Hogg-Dube Syndrome | Hepatitis, Autoimmune | Benign Familial Pemphigus | Rett Syndrome | Anosmia, Congenital | Hyperostosis | Greenberg Dysplasia | Kidney Stones | Sick Sinus Syndrome 1 | Myoclonic Atonic Epilepsy | Trachoma | Dubin-Johnson Syndrome | Spinal Cord Diseases | DiGeorge Syndrome | Lupus Erythematosus | Hepatic Veno-occlusive Disease | Panniculitis | Encephalopathy, Ethylmalonic | VACTERL/VATER Association | Paracoccidioidomycosis | Atrial Septal Defect | Premenstrual Syndrome | Familial Hemiplegic Migraine | Primary Sclerosing Cholangitis | Tardive Dyskinesia | Smith-Magenis Syndrome | Renal Failure | Retinopathy Of Prematurity | Stroke | Amelanotic Melanoma | Thromboembolism | Waldenstrom Macroglobulinemia | Plasmacytoma | AIDS | Congenital Tufting Enteropathy | Acrocallosal Syndrome | Anal Fissure | Roberts Syndrome | Large Granular Lymphocytic Leukemia | Proteus Syndrome | Pneumonia, Bacterial | Retinal Diseases | Pyoderma Gangrenosum | Esthesioneuroblastoma | Arts Syndrome | Chorea | Familial Hypertrophic Cardiomyopathy | Malignant Peripheral Nerve Sheath Tumor | Epidermolysis Bullosa Acquisita | Cholangitis | Hereditary Multiple Exostoses | Hepatopulmonary Syndrome | Moyamoya Disease | Nephrotic Syndrome Type 1 | IgA Deficiency | Diarrhea | KBG Syndrome | Sialidosis | Arrhythmogenic Right Ventricular Cardiomyopathy | Teratozoospermia | Batten Disease | Vestibular Disease | Meningitis | Hyperthermia, Malignant | Thyroid Hormone Resistance | Granuloma Annulare | Ventricular Septal Defect | B-cell Chronic Lymphocytic Leukemia | Keratopathy | Priapism | Myelitis, Transverse | Bruck Syndrome | Hereditary Sensory Neuropathy Type 1 | Pneumococcal Meningitis | Neonatal Progeroid Syndrome | Dyggve-Melchior-Clausen Disease | IgA Nephropathy | Crouzon Syndrome With Acanthosis Nigricans | Antiphospholipid Syndrome | Orthostatic Intolerance | Pfeiffer Syndrome | Hemolytic Anemia | Gingivitis | Viral Meningitis | Conn Syndrome | Adenosine Deaminase 2 Deficiency | Hereditary Pyropoikilocytosis | Epicondylitis | Metachromatic Leukodystrophy | Growth Hormone Excess | Multiple Sclerosis, Chronic Progressive | Rotor Syndrome | Neuroma | Schwannomatosis | VEXAS Syndrome | Keratitis | Sjogren Syndrome | Fibromyalgia | Ghosal Syndrome | Choroideremia | Tonsillitis | ICF Syndrome | Prurigo Nodularis | Peutz-Jeghers Syndrome | Lateral Meningocele Syndrome | Osteoglophonic Dysplasia | 3-methylcrotonyl-CoA Carboxylase Deficiency | Insulin Resistance | Duane Retraction Syndrome | Interstitial Lung Diseases | Wiskott-Aldrich Syndrome | Learning Disability | Giant Cell Arteritis | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Sclerosteosis | Medulloblastoma | Ovarian Sex Cord-stromal Tumor | Intellectual Disability, Autosomal Dominant 5 | Chondrosarcoma | Usher Syndrome Type III | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Congenital Stationary Night Blindness | Noonan Syndrome | Pemphigoid | Chondrodysplasia Punctata 2, X-linked Dominant | Primary Cutaneous Amyloidosis | Polydactyly | Cryoglobulinemia | Retinal Dystrophy, Early-onset Severe | Histiocytic Sarcoma | Niemann-Pick Disease, Type A | Apraxia | Goiter, Nodular | Perry Syndrome | Nail Disorder, Nonsyndromic Congenital | Stuttering | Pitt-Hopkins Syndrome | Keratosis, Seborrheic | Multiple Sclerosis | Synpolydactyly | Charcot-Marie-Tooth Disease, Type 2A | Pituitary Stalk Interruption Syndrome | Pernicious Anemia | Trichotillomania | Hereditary Neuropathy With Liability To Pressure Palsies | Goiter | Bursitis | Pseudoachondroplasia | Spinocerebellar Ataxia Type 6 | Coenzyme Q10 Deficiency | Insulinoma | Dentinogenesis Imperfecta | Chromosome 8q21.11 Deletion Syndrome | Hyperoxaluria | Scapuloperoneal Myopathy, X-linked Dominant | Progressive Osseous Heteroplasia | Graves Disease | Acromicric Dysplasia | Oligoasthenoteratozoospermia | Chloridorrhea, Congenital | Hyperkalemic Periodic Paralysis | Metabolic Syndrome | Rubeosis Iridis | Johanson-Blizzard Syndrome | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Anti-NMDA Receptor Encephalitis | Blue Rubber Bleb Nevus Syndrome | Tyrosinemia | Left Ventricular Noncompaction | Sclerosteosis 2 | Waardenburg Syndrome Type 2A | 3-methylglutaconic Aciduria Type I | Fibrosis | Juvenile Hyaline Fibromatosis | Congenital Heart Defects | Salla Disease | Vitamin B12 Deficiency | Encephalitis, Tick-borne | Gout | Atherosclerosis | Spitz Nevus | Long QT Syndrome Type 2 | Waardenburg Syndrome Type 4 | Congenital Hereditary Endothelial Dystrophy Type I | Hamartoma | Nephrocalcinosis | Infantile Neuroaxonal Dystrophy | Colitis, Collagenous | Obesity, Morbid | Autosomal Recessive Congenital Ichthyosis | Vascular Calcification | Cystitis, Interstitial | Papulopustular Rosacea | Succinic Semialdehyde Dehydrogenase Deficiency | Ellis-Van Creveld Syndrome | Hypertension, Portal | Atopic Dermatitis | Hepatoblastoma | Cancer, Bladder | Diabetes Type 1 | Hyperandrogenemia | Neurofibroma | Anencephaly | Babesiosis | Myelomeningocele | Pemphigus Foliaceus | Retinal Detachment | Camptocormia | Crisponi Syndrome | Alazami Syndrome | Cerebrovascular Disorders | Hypoparathyroidism | Ichthyosis, X-linked | Nephrosclerosis | Citrullinemia | Coffin-Lowry Syndrome | Orotic Aciduria | Placenta Previa | Progressive Familial Intrahepatic Cholestasis Type 3 | Aarskog-Scott Syndrome | Thyroiditis, Autoimmune | Low Tension Glaucoma | Xeroderma Pigmentosum Variant Type | Metabolic Diseases | Congenital Dyserythropoietic Anemia | Splenomegaly | Pulmonary Veno-occlusive Disease | Basal Ganglia Cerebrovascular Disease | Mast Cell Leukemia | Eosinophilia | Angiodysplasia | Celiac Disease | Neutropenia | Antley-Bixler Syndrome | Heart Block | Mitochondrial Cytopathy | Primary Lateral Sclerosis | Adrenomyeloneuropathy | Neurotoxicity | Eccrine Porocarcinoma | Beckwith-Wiedemann Syndrome | Krabbe Disease | Bronchiectasis | Triphalangeal Thumb-polysyndactyly Syndrome | Waardenburg Syndrome | Opisthorchiasis | Ischemia | Acute Generalized Exanthematous Pustulosis | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Familial Exudative Vitreoretinopathy | Central Core Disease | Limb Girdle Muscular Dystrophy | Myofibromatosis | Carbonic Anhydrase VA Deficiency | Nephrotic Syndrome | Tumoral Calcinosis | Charcot-Marie-Tooth Disease Type 4D | Cardiomyopathy, Dilated, 1L | Leukoencephalopathy, Progressive Multifocal | Hernia, Inguinal | Veno-occlusive Disease | Primary Progressive Aphasia | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Infantile Refsum Disease | Osteogenesis Imperfecta Type III | Subacute Sclerosing Panencephalitis | Hypotrichosis Simplex | Benign Recurrent Intrahepatic Cholestasis 1 | Meningococcal Meningitis | Aspartylglycosaminuria | Congenital Muscular Dystrophy | Adenoma, Pleomorphic | Congestive Heart Failure | Thrombosis | Neuropathy | Spinocerebellar Ataxia Type 17 | Atelosteogenesis Type 2 | Spondylolisthesis | Necrotizing Autoimmune Myopathy | Heavy Chain Disease | Pyruvate Carboxylase Deficiency Disease | Hemoglobinopathies | Hemangioendothelioma | Endometrial Hyperplasia | Cardiomyopathy, Peripartum | Glaucoma, Congenital | Christianson Syndrome | Tietze Syndrome | Congenital Hereditary Endothelial Dystrophy Type II | Maternally Inherited Diabetes And Deafness | Chordoma | Woodhouse-Sakati Syndrome | Pancreatitis | Molybdenum Cofactor Deficiency | Autonomic Nervous System Disorders | Supravalvular Aortic Stenosis | Persistent Fetal Circulation | Tyrosinemia Type 2 | Sarcomatoid Carcinoma Of The Lung | Enlarged Vestibular Aqueduct | Mevalonate Kinase Deficiency | Zygomycosis | Chylothorax, Congenital | Pycnodysostosis | Cold Agglutinin Disease | Jalili Syndrome | Melnick-Needles Syndrome | Osteoporosis, Postmenopausal | Familial Retinal Arterial Macroaneurysm | Asphyxia Neonatorum | Coloboma | Glomerulonephritis, Membranous | Glycogen Storage Disease Type 5 | Pulmonary Alveolar Proteinosis | Diabetes Insipidus | Intestinal Pseudo-obstruction | Tetanus | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Seizures-scoliosis-macrocephaly Syndrome | Vasculitis | Scapuloperoneal Spinal Muscular Atrophy