Disease

Multicystic Renal Dysplasia

About the Disease
Multicystic Dysplastic Kidney, also known as multicystic kidney dysplasia, is related to congenital anomalies of kidney and urinary tract 2 and cakut. An important gene associated with Multicystic Dysplastic Kidney is PKD1 (Polycystin 1, Transient Receptor Potential Channel Interacting), and among its related pathways/superpathways are p70S6K Signaling and Bardet-Biedl syndrome. The drugs Pharmaceutical Solutions and Ibuprofen have been mentioned in the context of this disorder. Affiliated tissues include kidney, testis and uterus, and related phenotypes are nervous system and renal/urinary system

Common Targets
PAX2 | ACE | AGTR1 | REN | HNF1B

疾病靶点研报
Multicystic Renal Dysplasia

Note: If you'd like to get a target analysis report for Multicystic Renal Dysplasia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Multicystic Renal Dysplasia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Primary Cutaneous Amyloidosis | Chordoma | Trichomegaly | Keratitis-ichthyosis-deafness Syndrome | Hypersensitivity | Carbamoyl Phosphate Synthetase I Deficiency | Chronic Neutrophilic Leukemia | Hepatic Steatosis | Keratopathy | Epithelial-myoepithelial Carcinoma | N-acetylglutamate Synthase Deficiency | Potocki-Shaffer Syndrome | Angioedema, Acquired | Peroxisomal Disorder | Anemia | Patent Ductus Arteriosus | Kidney Stones | Optic Neuropathy, Anterior Ischemic | Hereditary Folate Malabsorption | Paraplegia | Lathosterolosis | Choroideremia | Chylothorax, Congenital | Skin Papilloma | Neuroblastoma | Eosinophilic Asthma | Hypothyroidism | Charcot-Marie-Tooth Disease Type 2T | Marinesco-Sjogren Syndrome | Personality Disorders | Dysgerminoma | Familial Hemiplegic Migraine | Hypotrichosis | Supravalvular Aortic Stenosis | Corneal Dystrophy | Myasthenia | Chronic Thromboembolic Pulmonary Hypertension | Vitamin K Deficiency | Familial Pheochromocytoma-paraganglioma | Coronary Artery Disease | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Nasodigitoacoustic Syndrome | Hyperglycemia | Distal Spinal Muscular Atrophy | CHARGE Syndrome | GM2-gangliosidosis AB Variant | Cushing Syndrome | Hydrocephalus | Rhabdomyosarcoma, Embryonal | Vitiligo | Glycogen Storage Disease | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Aspergillosis | Harlequin Ichthyosis | Anorectal Fistula | Early Infantile Epileptic Encephalopathy 4 | Olmsted Syndrome | Temporal Lobe Epilepsy | Fanconi Anemia | Necrobiosis Lipoidica | Coma | Esophagitis | Retinal Vasculitis | Hemimegalencephaly | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Beckwith-Wiedemann Syndrome | Cutaneous Mastocytosis | Epilepsy | Congenital Bilateral Absence Of Vas Deferens | Hyperlipidemia, Familial Combined | Pontocerebellar Hypoplasia Type 7 | Protein S Deficiency | Charcot-Marie-Tooth Disease, Type 1A | Exostoses | Albinism | Methylmalonic Acidemia | Autosomal Recessive Spastic Paraplegia Type 35 | Retinitis Pigmentosa | Neovascular Glaucoma | Hamartoma | Purpura, Thrombotic Thrombocytopenic | Bullous Pemphigoid | Infantile Neuroaxonal Dystrophy | Enhanced S-cone Syndrome | Primary Progressive Aphasia | Glycogen Storage Disease Type 0, Muscle | Insulin Resistance | Atrial Septal Defect | Oculocutaneous Albinism Type 1 | Neurocutaneous Syndromes | Viral Meningitis | Pancytopenia | Astrocytoma, Anaplastic | Brugada Syndrome 1 | Porphyria, Acute Intermittent | Glucagonoma | Chronic Myelomonocytic Leukemia | Autoimmune Polyendocrine Syndrome | Alzheimer Disease, Late Onset | Hemoglobinopathies | Spinocerebellar Ataxia Type 1 | Aneurysm, Abdominal Aortic | Diastrophic Dysplasia | Ichthyosis, X-linked | Carpal Tunnel Syndrome | Werner's Syndrome | Spinal Muscular Atrophy | Chromosome 17q21.31 Deletion Syndrome | Galactosialidosis | Heterotaxy | Veno-occlusive Disease | Dystonia | Addison Disease | Growth Hormone Excess | Kashin-Beck Disease | Periodic Limb Movement Disorder | Muscular Dystrophy | Spinocerebellar Ataxia Type 8 | Strabismus | Retinoschisis | Familial Mediterranean Fever | Diamond-Blackfan Anemia | Spinocerebellar Ataxia Type 27 | Chorioretinitis | Keratosis, Seborrheic | Myofibromatosis | Overactive Bladder | Poretti-Boltshauser Syndrome | Arteriovenous Malformations | Hemorrhagic Disorders | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Dengue Shock Syndrome | Down Syndrome | Autonomic Nervous System Disorders | Nephritis, Interstitial | Stevens-Johnson Syndrome | Compartment Syndrome | Alveolar Capillary Dysplasia | Purpura | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Focal Dermal Hypoplasia | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Swine Influenza | Discoid Lupus Erythematosus | Adult Polyglucosan Body Disease | Epilepsy, Generalized | Branchiootorenal Syndrome | Familial Hyperaldosteronism | Mandibuloacral Dysplasia With Type A Lipodystrophy | Amelogenesis Imperfecta | Creutzfeldt-Jakob Disease | Pontocerebellar Hypoplasia Type 2 | Hereditary Mixed Polyposis Syndrome | Seborrheic Dermatitis | Hemangioma | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Acute Myeloid Leukemia | Methylmalonic Aciduria And Homocystinuria, CblC Type | Spondylo-ocular Syndrome | Otopalatodigital Syndrome Type 2 | Chiari Malformation Type I | Cardiospondylocarpofacial Syndrome | Myocardial Infarction | Hodgkin Lymphoma | Pachyonychia Congenita | Cancer, Breast | Meningococcal Meningitis | Pheochromocytoma | Hypoglycemia | Saul-Wilson Syndrome | Renpenning Syndrome | Leprosy | Hereditary Spherocytosis | Barrett Esophagus | Orthostatic Intolerance | Anencephaly | Psoriasis | Gingivitis | Niemann-Pick Disease, Type C | Borderline Personality Disorder | Scapuloperoneal Myopathy, X-linked Dominant | Dermatitis | Follicular Dendritic Cell Sarcoma | Lesch-Nyhan Syndrome | Protein C Deficiency | Charcot-Marie-Tooth Disease Type 4D | Lipoma | Porphyria Cutanea Tarda | Corneal Dystrophy And Perceptive Deafness | VACTERL Association | Apert Syndrome | Antithrombin III Deficiency | Spinocerebellar Ataxia Type 2 | Early Infantile Epileptic Encephalopathy 1 | Atelosteogenesis Type 2 | Charcot-Marie-Tooth Disease Type 2D | Encephalopathy, Hepatic | Waardenburg Syndrome | Sporadic Hemiplegic Migraine | Sorsby Fundus Dystrophy | Cystinuria | Polycystic Ovary Syndrome | Pyloric Stenosis, Infantile Hypertrophic | Myotonic Disorders | Lymphangioma | Spinal And Bulbar Muscular Atrophy | Xeroderma Pigmentosum | Schamberg Disease | Thyroid Dyshormonogenesis | HELLP Syndrome | Headache | Stroke | Meniere's Disease | Asthma | Primary Torsion Dystonia | Congenital Dysfibrinogenemia | Histiocytosis | Mohr-Tranebjaerg Syndrome | Blau Syndrome | Myositis, Focal | Melanoma | Hyperparathyroidism, Secondary | Uterine Leiomyoma | Dyslexia | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Syndactyly | Charcot-Marie-Tooth Disease Type 4E | Amyotrophic Lateral Sclerosis | Charcot-Marie-Tooth Disease Type 3 | Glycogen Storage Disease Type 1b | Partington Syndrome | Tietze Syndrome | Hartsfield Syndrome | Charcot-Marie-Tooth Disease Type 4B1 | Bicuspid Aortic Valve | Infantile Spasm | Leukoplakia | Dent Disease | Frontotemporal Dementia | Epidermolytic Hyperkeratosis | Carpenter Syndrome | Micropenis | Spinocerebellar Ataxia Type 38 | Sitosterolemia | Multiple Myeloma | Intellectual Disability, Autosomal Dominant 5 | Antenatal Bartter Syndrome Type 1 | Cantu Syndrome | Dyskeratosis Congenita | Palmoplantar Keratoderma | Hereditary Sensory And Autonomic Neuropathy | Holoprosencephaly | Mucolipidosis Type III | Multiple Hamartoma Syndrome | Extramammary Paget's Disease | Alcoholism | Combined Deficiency Of Factor V And Factor VIII | Vici Syndrome | Multicystic Renal Dysplasia | Thrombocythemia, Essential | Opisthorchiasis | Hypertelorism | Mitochondrial DNA Depletion Syndrome | Androgenic Alopecia | Scleritis | Erythropoietic Protoporphyria | Polyneuropathy | Episodic Ataxia Type 1 | Sarcosinemia | Nemaline Myopathy 10 | Polycystic Kidney, Autosomal Recessive | Seizures-scoliosis-macrocephaly Syndrome | Pyruvate Decarboxylase Deficiency | Wolfram Syndrome | Neuropathy | Giant Axonal Neuropathy | Glycogen Storage Disease Type 5 | Usher Syndrome Type II | Donnai-Barrow Syndrome | AIDS Dementia Complex | Acute Lymphocytic Leukemia | Uremia | Gout | Leukemia | Atherosclerosis | Borjeson-Forssman-Lehmann Syndrome | Hyperacusis | Hyperandrogenemia | Peutz-Jeghers Syndrome | Avellino Corneal Dystrophy | Fuchs Heterochromic Iridocyclitis | Graves Disease | Cardiomyopathy, Restrictive | Chediak-Higashi Syndrome | Pericarditis | Leber Hereditary Optic Neuropathy | Cranial Nerve Disease | Zellweger Syndrome | Hypoalbuminemia | Hypotrichosis Simplex | Alpers Syndrome | Blepharoconjunctivitis | Epiphyseal Chondrodysplasia, Miura Type | Thrombophilia | Glomerulonephritis, Membranoproliferative | Acrocallosal Syndrome | Yellow Fever | Vertebrobasilar Insufficiency | Hypogonadism | Carbonic Anhydrase VA Deficiency | High Molecular Weight Kininogen Deficiency | Early Infantile Epileptic Encephalopathy 28 | Oculocutaneous Albinism Type 4 | Proteus Syndrome | Spinocerebellar Ataxia Type 16 | Raynaud Phenomenon | X-linked Acrogigantism | Multicentric Carpotarsal Osteolysis Syndrome | Left Ventricular Noncompaction | Otitis Media | Infantile Nephropathic Cystinosis | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Hyperkeratosis | Pure Red Cell Aplasia | Hennekam Lymphangiectasia-lymphedema Syndrome | Mountain Sickness | Schwannomatosis | Stomatitis | Hyperinsulinism-hyperammonemia Syndrome | Restrictive Dermopathy | Pyoderma Gangrenosum | Martsolf Syndrome | Neurocutaneous Melanocytosis | Japanese Encephalitis | Shock, Cardiogenic | Pre-eclampsia | Nicolaides-Baraitser Syndrome | Babesiosis | Mitochondrial Myopathy | Warsaw Breakage Syndrome | Adenomyosis | Senior-Loken Syndrome | Anorexia Nervosa | Autosomal Recessive Spastic Paraplegia Type 54 | Hypoparathyroidism | Renal Hypomagnesemia 3 | Rosacea | Isovaleric Acidemia | Gerodermia Osteodysplastica | Sarcoidosis, Pulmonary | Cyclic Vomiting Syndrome | Camurati-Engelmann Disease | Tuberculous Meningitis | Renal Failure | Ocular Albinism Type 1 | Liver Failure, Acute Infantile | Omenn Syndrome | Menetrier Disease | Rhabdomyosarcoma | Meckel-Gruber Syndrome | Presbycusis | Aspartylglycosaminuria | Hypotonia-cystinuria Syndrome | Fetal Akinesia Deformation Sequence | DRESS Syndrome | Retinitis | Cancer, Lung | Asphyxia Neonatorum | Erdheim-Chester Disease | Tularemia | Aphasia | Juvenile Xanthogranuloma | Asthma, Nocturnal | Endometrial Hyperplasia | Congenital Lipoid Adrenal Hyperplasia | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Migraine | Cholera | Congenital Disorders Of Glycosylation Type II | Hereditary Hemorrhagic Telangiectasia | Blastomycosis | Atelosteogenesis Type 1 | Guanidinoacetate Methyltransferase Deficiency | Influenza | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Cholelithiasis | Inflammatory Myopathy | Asperger Syndrome | Congenital Muscular Dystrophy | Mannosidase Deficiency Diseases | Stroke, Hemorrhagic | Guillain-Barre Syndrome | Diarrhea | Epilepsy Of Infancy With Migrating Focal Seizures | Birt-Hogg-Dube Syndrome | Intermittent Explosive Disorder | Congenital Dyserythropoietic Anemia | Skin Fragility-woolly Hair Syndrome | Celiac Disease