Multicystic Renal Dysplasia

About the Disease
Multicystic Dysplastic Kidney, also known as multicystic kidney dysplasia, is related to congenital anomalies of kidney and urinary tract 2 and cakut. An important gene associated with Multicystic Dysplastic Kidney is PKD1 (Polycystin 1, Transient Receptor Potential Channel Interacting), and among its related pathways/superpathways are p70S6K Signaling and Bardet-Biedl syndrome. The drugs Pharmaceutical Solutions and Ibuprofen have been mentioned in the context of this disorder. Affiliated tissues include kidney, testis and uterus, and related phenotypes are nervous system and renal/urinary system

Common Targets
PAX2 | ACE | AGTR1 | REN | HNF1B

Note: If you'd like to get a target analysis report for Multicystic Renal Dysplasia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Multicystic Renal Dysplasia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Chorioretinitis | Pseudohypoparathyroidism Type 1A | Botulism | Ventricular Septal Defect | Polymicrogyria | 3C Syndrome | Keratitis | Trimethylaminuria | Thrombophlebitis | Narcolepsy | Hypoproteinemia, Hypercatabolic | Parkinson's Disease | Epidermodysplasia Verruciformis | Angioimmunoblastic T-cell Lymphoma | Perry Syndrome | Facioscapulohumeral Muscular Dystrophy Type 1 | Diamond-Blackfan Anemia | Eosinophilic Asthma | Malnutrition | Liver Failure | Gangliosidosis, GM1 | Potocki-Shaffer Syndrome | Chudley-McCullough Syndrome | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Cardiomyopathy, Hypertrophic | Malignant Fibrous Histiocytoma | Plasmacytoma | Mitochondrial Myopathy | Hidradenitis | Hyperuricemia | Dystonia | Polymyositis | Hyperparathyroidism, Secondary | Stiff-man Syndrome | Familial Glucocorticoid Deficiency | Familial Episodic Pain Syndrome | Otosclerosis | Aneurysm, Thoracic Aortic | Rift Valley Fever | Congenital Afibrinogenemia | Diabetes Insipidus, Neurogenic | Kidney Stones | Castleman Disease | Sarcosinemia | Bronchiolitis | Seborrheic Dermatitis | Carpal Tunnel Syndrome | Nemaline Myopathy | Language Disorders | Pyloric Stenosis, Infantile Hypertrophic | Hepatitis E | Sarcoma, Ewing | Epilepsy, Generalized | Microphthalmia, Syndromic 7 | Sclerosteosis | Isovaleric Acidemia | Hypertension, Portal | Arthritis, Reactive | Familial Hypobetalipoproteinemia | Von Willebrand Disease | Glanzmann Thrombasthenia | Omenn Syndrome | Rothmund-Thomson Syndrome | Autosomal Recessive Spastic Paraplegia Type 35 | Hepatitis A | Rosacea | Addison Disease | Schuurs-Hoeijmakers Syndrome | Agranulocytosis | Porphyria | Peroxisomal Disorder | Distal Myopathy 2 | Paracoccidioidomycosis | Gigantism | PHARC Syndrome | X-linked Acrogigantism | Acute Leukemia | Parvovirus B19 Infection | Opisthorchiasis | Spinocerebellar Ataxia Type 15 | Metachondromatosis | Primrose Syndrome | Congenital Myopathy | Campomelic Dysplasia | Hypertensive Nephropathy | Pyruvate Dehydrogenase Deficiency | Metatropic Dysplasia | Ophthalmia, Sympathetic | Mast Cell Leukemia | Giant Axonal Neuropathy | Cold-induced Sweating Syndrome | Charcot-Marie-Tooth Disease, Type 6 | Juvenile Hyaline Fibromatosis | Pupil Disorders | Primary Torsion Dystonia | Non-bullous Congenital Ichthyosiform Erythroderma | Chronic Periodontitis | Veno-occlusive Disease | Spinocerebellar Ataxia Type 28 | Wilson's Disease | Huntington's Disease | Torticollis | Long QT Syndrome Type 3 | Dystrophy, Cone-rod | VACTERL Association | Scapuloperoneal Myopathy, X-linked Dominant | Coenzyme Q10 Deficiency | Diabetes Type 1 | Myelofibrosis | Neuroleptic Malignant Syndrome | Pfeiffer Syndrome | Necrobiosis Lipoidica | Inflammatory Myofibroblastic Tumor | Herpes Genitalis | Pulmonary Capillary Hemangiomatosis | Migraine | Fatty Aldehyde Dehydrogenase Deficiency | Myoclonic Atonic Epilepsy | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | CREST Syndrome | 3-hydroxy-3-methylglutaric Aciduria | Tyrosinemia Type 1 | Mannosidase Deficiency Diseases | Paroxysmal Kinesigenic Dyskinesia | Asthma | Lattice Corneal Dystrophy | Inflammatory Myopathy | Amyotrophic Lateral Sclerosis, Juvenile | Achondrogenesis | Dengue Hemorrhagic Fever | Communication Disorders | Analgesia | Bipolar Disorder | Withdrawal Syndrome | Glutathione Synthetase Deficiency | Hereditary Neuropathy With Liability To Pressure Palsies | Spondylosis | Hyperferritinemia-cataract Syndrome | Congenital Heart Defects | Thalassemia, Beta | Hypokalemia | Wieacker-Wolff Syndrome | Myofibromatosis | Panniculitis | Lipodystrophy | Primary Pigmented Nodular Adrenocortical Disease | Seizures-scoliosis-macrocephaly Syndrome | Familial Cerebral Amyloid Angiopathy | Vasculitis | Duodenal Atresia | Central Pain Syndrome | Vascular Cognitive Impairment | Cystinuria | Hepatitis | Dementia, Vascular | Thalassemia | Cold Agglutinin Disease | Tonsillitis | DRESS Syndrome | Astigmatism | Hereditary Folate Malabsorption | Hernia, Inguinal | Hereditary Sensory And Autonomic Neuropathy | Prader-Willi Syndrome | Cancer, Prostate | Melanoma, Uveal | Waardenburg Syndrome Type 4 | Encephalopathy | Persistent Truncus Arteriosus | Diffuse Intrinsic Pontine Glioma | Raynaud Phenomenon | Congenital Heart Block | Schizophrenia | Osteogenesis Imperfecta Type III | Ligneous Conjunctivitis | Nanophthalmos | Goiter | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Idiopathic Multicentric Castleman Disease | Hypervalinemia | Mitochondrial DNA Depletion Syndrome | Dysfibrinogenemia | Parapsoriasis | Left Ventricular Noncompaction | Esthesioneuroblastoma | Meesmann Corneal Dystrophy | Sarcomatoid Carcinoma Of The Lung | Rhabdomyosarcoma, Embryonal | Budd-Chiari Syndrome | Spinocerebellar Ataxia Type 2 | Osteoporosis, Postmenopausal | Keratosis, Seborrheic | 3-M Syndrome | Erectile Dysfunction | Spinocerebellar Ataxia Type 3 | Generalized Epilepsy And Paroxysmal Dyskinesia | Myositis | Vitreoretinal Degeneration, Snowflake Type | Lyme Disease | Sclerosing Cholangitis | Multiple Sclerosis, Primary Progressive | Reye Syndrome | Gliosarcoma | Congenital Torticollis | Infantile Liver Failure Syndrome 1 | Cancer, Lung | Peritonitis | Bernard-Soulier Syndrome | Keratoconus | Charcot-Marie-Tooth Disease Type 4B1 | Cramp Fasciculation Syndrome | Megaloblastic Anemia | Fibromuscular Dysplasia | Smith-Lemli-Opitz Syndrome | Personality Disorders | Acrodermatitis | Progressive Familial Intrahepatic Cholestasis Type 2 | Cholangiocarcinoma | Ichthyosis, X-linked | Intracranial Hypertension | Subcortical Band Heterotopia | Dengue Shock Syndrome | Diabetes Mellitus, Transient Neonatal | Absence Epilepsy | Pelizaeus-Merzbacher Disease | Hypobetalipoproteinemias | Gastroschisis | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Chronic Inflammatory Demyelinating Polyneuropathy | Lamellar Ichthyosis | Episodic Ataxia | Congenital Dysfibrinogenemia | Tremor | Splenomegaly | Cholecystitis | Spinocerebellar Ataxia Type 8 | Hyperhomocysteinemia | Pernicious Anemia | Retinal Dystrophy | Crimean-Congo Hemorrhagic Fever | Dysthymia | Neurodevelopmental Disorders | Familial Exudative Vitreoretinopathy | Cerebral Amyloid Angiopathy | Geleophysic Dysplasia | Thrombocytopenia | Uveitis | Exostoses | Periodic Limb Movement Disorder | Familial Thoracic Aortic Aneurysm | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Alpha-mannosidosis | Proopiomelanocortin Deficiency | Hypermetropia | Plasma Cell Leukemia | Multiple Myeloma | Fetal And Neonatal Alloimmune Thrombocytopenia | Nephroblastoma | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Epilepsy Of Infancy With Migrating Focal Seizures | Neuromuscular Disorders | Bronchitis | Specific Granule Deficiency | Ovarian Sex Cord-stromal Tumor | Scabies | Eclampsia | Mucolipidosis Type II | Wolfram Syndrome 2 | Neurofibromatosis Type 2 | Oculocutaneous Albinism Type 1 | Tricho-hepato-enteric Syndrome | Hypodontia | Hypoplastic Left Heart Syndrome | Chromosome 16p11.2 Deletion Syndrome | Heterotaxy | Combined Pituitary Hormone Deficiency | Aphasia | Long QT Syndrome Type 2 | Progressive Familial Intrahepatic Cholestasis | Lennox-Gastaut Syndrome | Waardenburg Syndrome Type 2A | Ureteropelvic Junction Obstruction | Giant Cell Glioblastoma | Smith-Kingsmore Syndrome | Pyruvate Decarboxylase Deficiency | Nephrotic Syndrome | Cancer, Colon | Sickle Cell Disease | Pouchitis | Neurofibrosarcoma | Lymphoma Lymphoblastic | Gnathodiaphyseal Dysplasia | Sleep Disorder | Galactosialidosis | 3-methylglutaconic Aciduria Type I | Retinopathy, Diabetic | Empyema | Hyperinsulinemic Hypoglycemia | Blastomycosis | Lentigo | Exfoliative Dermatitis | Pyruvate Kinase Deficiency | Vitamin A Deficiency | Hodgkin Lymphoma | Primary Progressive Aphasia | Gaucher Disease | Lichen Sclerosus | Blastoma, Pleuropulmonary | Bronchiectasis | Chronic Thromboembolic Pulmonary Hypertension | Ichthyosis | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Hyperthyroidism | Myopia | Spinocerebellar Ataxia Type 21 | Coloboma | Cystitis, Interstitial | Tangier Disease | Cholelithiasis | Cholestasis, Intrahepatic | Obesity | Cutaneous Mastocytosis | Best Macular Dystrophy | Depression | Aromatic L-amino Acid Decarboxylase Deficiency | Diastrophic Dysplasia | Congenital Ichthyosiform Erythroderma | Trichothiodystrophy | Papillorenal Syndrome | Urolithiasis | Congenital Generalized Lipodystrophy | Glioblastoma Multiforme | Carbamoyl Phosphate Synthetase I Deficiency | Lassa Fever | Lateral Meningocele Syndrome | Birk-Barel Syndrome | Nutrition Disorders | Hyperekplexia | Spinal Muscular Atrophy Type 2 | Pierson Syndrome | GLUT1 Deficiency Syndrome | Adams-Oliver Syndrome | Portal Vein Thrombosis | Osteogenesis Imperfecta | Connective Tissue Disorders | Intracerebral Hemorrhage | Nasodigitoacoustic Syndrome | Hereditary Coproporphyria | Hypersensitivity Pneumonitis | Hypersomnia | Oligoasthenoteratozoospermia | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Marfan Syndrome | Hemochromatosis | Warsaw Breakage Syndrome | Glaucoma, Congenital | Blepharoconjunctivitis | Netherton Syndrome | Keratosis | Niemann-Pick Disease, Type C | Trichomegaly | Microcephalic Primordial Dwarfism | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Schaaf-Yang Syndrome | Congestive Heart Failure | Poretti-Boltshauser Syndrome | Guillain-Barre Syndrome | NGLY1 Deficiency | Lipid Metabolism Disorders | Adenosine Deaminase 2 Deficiency | Mastitis | Leiomyoma | Pemphigus Vulgaris | Swine Influenza | Neovascular Glaucoma | Hartnup Disease | Sensory Neuropathy | Persistent Hyperplastic Primary Vitreous | Alveolar Capillary Dysplasia | C3 Glomerulopathy | Endocarditis | Spondylo-ocular Syndrome | Actinomycetoma | Thanatophoric Dysplasia | Pierpont Syndrome | X-linked Creatine Transporter Deficiency | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Maternally Inherited Diabetes And Deafness | Spitzoid Melanoma | Interstitial Lung Diseases | Spinocerebellar Ataxia Type 5 | Heterotopic Ossification | Angiodysplasia | Thanatophoric Dysplasia Type 1 | Subacute Sclerosing Panencephalitis | Pseudo-pseudohypoparathyroidism | Filariasis | Proteasome-associated Autoinflammatory Syndrome 2 | DOCK8 Immunodeficiency Syndrome | Oligoastrocytoma