Pendred Syndrome

About the Disease
Pendred Syndrome, also known as goiter-deafness syndrome, is related to congenital hypothyroidism and goiter. An important gene associated with Pendred Syndrome is SLC26A4 (Solute Carrier Family 26 Member 4), and among its related pathways/superpathways are Disorders of transmembrane transporters and Thyroxine (thyroid hormone) production. Affiliated tissues include thyroid, testis and kidney, and related phenotypes are sensorineural hearing impairment and hypoplasia of the cochlea

Common Targets
DUOX2 | FOXI1 | EPHA2 | SCARB2 | SLC26A4 | GJB2

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