PASLI Disease

About the Disease
Immunodeficiency 14, also known as activated pi3k-delta syndrome, is related to immunodeficiency 14a, autosomal dominant and agammaglobulinemia, x-linked. An important gene associated with Immunodeficiency 14 is PIK3CD (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta), and among its related pathways/superpathways are Innate Immune System and Signal Transduction. The drugs Miconazole and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include t cells, b cells and prefrontal cortex, and related phenotypes are Decreased viability and Decreased viability

Common Targets
PIK3CD | PIK3R1

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