Alexander Disease

About the Disease
Alexander Disease, also known as alexander's disease, is related to leukodystrophy and multiple system atrophy 1, and has symptoms including muscle spasticity and seizures. An important gene associated with Alexander Disease is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Signaling by Receptor Tyrosine Kinases and Neuroscience. The drug Metronidazole has been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and eye, and related phenotypes are macrocephaly and intellectual disability

Common Targets
GFAP | MALAT1 | HDAC6 | THRA | MALT1 | THRB

Note: If you'd like to get a target analysis report for Alexander Disease, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Alexander Disease at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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