Disease

Chorea

About the Disease
Choreatic Disease, also known as chorea, is related to chorea, benign hereditary and chorea gravidarum, and has symptoms including ataxia, athetosis and clonus. An important gene associated with Choreatic Disease is FRRS1L (Ferric Chelate Reductase 1 Like), and among its related pathways/superpathways are G alpha (s) signalling events and Rett syndrome causing genes. The drugs Dopamine and Amantadine have been mentioned in the context of this disorder. Affiliated tissues include brain, bone marrow and globus pallidus, and related phenotypes are nervous system and behavior/neurological

Common Targets
SLC18A2 | G23411 | PDE10A | XDH | TSFM | PTPN1 | AKR1B1 | PRRT2 | SLC17A8 | MRPS22 | VPS13A | ADCY5 | EIF4G1 | STS | GAA | PDE2A | CACNA1A | SLC2A1 | DCTN1 | SCN5A | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | ALDH5A1 | XK | BDNF | G1956 | COMT | MAOA

疾病靶点研报
Chorea

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