Gynecomastia

About the Disease
Gynecomastia is related to 17-beta hydroxysteroid dehydrogenase iii deficiency and androgen insensitivity, partial. An important gene associated with Gynecomastia is CYP19A1 (Cytochrome P450 Family 19 Subfamily A Member 1), and among its related pathways/superpathways are Metabolism of proteins and Signal Transduction. The drugs (R)-Bicalutamide and Tamoxifen have been mentioned in the context of this disorder. Affiliated tissues include breast, prostate and testis, and related phenotypes are homeostasis/metabolism and nervous system

Common Targets
Estrogen receptor (nonspecified subtype) | CRBN | CYP19A1 | G2099 | Protein kinase C (nonspecified subtype)

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