Retinitis Pigmentosa

About the Disease
Cone-Rod Dystrophy 2, also known as cone-rod dystrophy, is related to cone-rod dystrophy 3 and cone-rod dystrophy 16. An important gene associated with Cone-Rod Dystrophy 2 is CRX (Cone-Rod Homeobox), and among its related pathways/superpathways are Bardet-Biedl syndrome and Ciliopathies. The drugs Tocopherol and Acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include Eye, and related phenotypes are abnormality of retinal pigmentation and photophobia

Common Targets
ZBED1 | HDAC1 | SPATA7 | Alpha-2 Adrenergic receptors (nonspecified subtype) | Folate Receptor (nonspecified subtype) | RARA | CNGA3 | NGFR | PEX26 | F13A1 | HGSNAT | REEP6 | MYO7B | SYNJ1 | POMGNT1 | FLG | RPGRIP1L | FAM161A | GUCY2D | G23411 | SIGMAR1 | TRIP13 | G842 | GON4L | BSG | MPDZ | CA1 | F2 | CDC73 | PKD2 | CHM | ZDHHC24 | TRIP12 | PRPH2 | NPHP4 | CFAP418 | SAG | SNU13 | PDE10A | SNRNP200 | ZEB2 | NEUROD1 | CLCC1 | Integrin Receptor (nonspecified subtype) | SCLT1 | CYP4V2 | ALG12 | CEP250 | BBS2 | Serine palmitoyltransferase | PDE6A | ABHD12 | THEGL | NTRK1 | ESX1 | EML4 | G7422 | CLN3 | SERPINE1 | AVPR2 | SHOX | UNC119 | TEX15 | ATP10B | RET | RHO | OAT | CLK4 | MUC1 | ABHD16A | CRX | RAX2 | ATP7A | TUBGCP6 | RPGRIP1 | CERKL | KIF3B | LCA5 | FTSJ1 | ZNF513 | MAK | RBP4 | PDE5A | Integrin alphavbeta5 receptor | GP5 | ROM1 | Chaperone (nonspecified subtype) | ARL3 | GRK1 | PRPF8 | IMPDH1 | ATXN7L1 | TOPORS | CA7 | PCDH15 | FLVCR1 | GUCA1A | CEP290 | CFAP20 | CHRM3 | TEKT4 | DZIP1L | MVK | TET1 | ABCA4 | CWC27 | NF-kappaB (NFkB) | IQCB1 | AAR2 | MERTK | TBP | ADGRV1 | TULP1 | BBS7 | NMDA receptor | HRNR | NOS2 | PDE6B | FSCN2 | RDH5 | PRPF6 | PRPF31 | F5 | FGB | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | ERBB4 | SLC4A7 | RLBP1 | PDE4DIP | FASLG | ATP6V1F | GNL3 | ROCK2 | GUCA1B | UBR2 | NRL | EYS | NLRP3 Inflammasome | SCN9A | DHX38 | MTREX | ALMS1 | DHDDS | CAPN1 | TEX13C | SEC24A | G114548 | SPANXD | G196 | ADIPOR1 | FGF10 | MAGI3 | HMCN1 | SIRPB1 | WDR19 | RP9 | ARMS2 | CSF2 | CA2 | RP1 | CLDN5 | NPHP3 | PRPF4B | MST1L | FGF10-AS1 | PKM | PROM1 | IMPG1 | POC5 | SEMA4A | HK1 | USH2A | PDZD7 | GRID2 | PITPNM3 | LTN1 | B3GALT2 | RORB | CYP26A1 | GGCX | CA9 | IMPG2 | DYNC2H1 | CLK1 | ATP6 | VCP | MDN1 | CFH | APP | TDRD6 | PRKAR2A | ACACB | ALPK3 | PRDM13 | MUC3A | PTBP2 | RBP3 | RP2 | SI | Potassium Channels (nonspecified subtype) | TRAIP | ABCC1 | ARL6 | HTT-AS | CDHR1 | RDH12 | ERN1 | RPGR | BEST1 | SCAPER | ADAM9 | HPSE | C1QTNF5 | AKR1B10 | KRR1 | CNGB1 | IDH3A | DHFR | TTC8 | LRP2 | HTT | PCDHB14 | SDCCAG8 | DLX6 | ESRRG | PCARE | TTLL5 | CRB1 | RIPK1 | COL11A1 | CRB2 | Rho kinase (ROCK) (nonspecified subtype) | Integrin alphavbeta1 | DMBT1 | OPA1 | WHRN | CLRN1 | RHBDD2 | COL2A1 | EMC1 | PANK2 | PEX1 | KLHL7 | RPL14 | CNGA1 | TRIM32 | TREX1 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | ZNF408 | RDH11 | ATP8 | PALS2 | COL6A3 | FLG-AS1 | CYP4A11 | CFAP410 | FRG1 | PDE6G | G5347 | ABCC3 | MFRP | USH1C | WDPCP | KIZ | SYTL3 | G8878 | CR1L | RPE65 | G4780 | LRAT | Integrin alpha2beta1 (VLA-2) receptor | CDH23 | MFSD8 | MC1R | PRCD | MKKS | EFTUD2 | CLK2 | CNOT3 | IFT140 | VCAN | Melanocortin receptor (nonspecified subtype) | HKDC1 | PRPF4 | RP1L1 | SCN2A | AGBL5 | CACNA1F | BBS1 | BRD9 | PDHA2 | mu-Calpain (calpain 1) | UBR1 | PPARA | SOS1 | PRPF3 | NOP56 | SF3B2 | APEH | ADAR | COL6A6 | Integrin alphavbeta3 (vitronectin) receptor | NPHP1 | BBS10 | TTC26 | SLC7A14 | G1956 | MTHFR | CTSD | AIPL1 | NR2E3 | NEK2 | CA4 | PRPS1 | TGFBI | FFAR4 | CEP78 | AHI1 | ABCA13 | ARL2BP | CNGB3 | IFT172 | TJP2 | OTX2 | MXRA5 | TNFRSF1B | FAM110C | OFD1 | MYO7A | PPP1R15A | CFAP74

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