Heart Block

About the Disease
Atrial Standstill 1, also known as cardiomyopathy, familial, with conduction disturbance, is related to atrial standstill and syncope, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Atrial Standstill 1 is GJA5 (Gap Junction Protein Alpha 5), and among its related pathways/superpathways are DREAM Repression and Dynorphin Expression and "Antiarrhythmic Pathway, Pharmacodynamics". The drugs Carvedilol and Milrinone have been mentioned in the context of this disorder. Affiliated tissues include heart, bone marrow and skeletal muscle, and related phenotypes are ventricular escape rhythm and paroxysmal atrial fibrillation

Common Targets
DNAI1 | MUC5B | NPHP3 | TTN | SCN5A

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