Disease

Intermittent Claudication

About the Disease
Intermittent Claudication, also known as amyotrophic lateral sclerosis, is related to peripheral artery disease and angina pectoris, and has symptoms including back pain, headache and pain. An important gene associated with Intermittent Claudication is SELP (Selectin P), and among its related pathways/superpathways are Signal Transduction and ERK Signaling. The drugs Vorapaxar and Thrombin have been mentioned in the context of this disorder. Affiliated tissues include Placenta, bone marrow and spinal cord, and related phenotypes are no effect and no effect

Common Targets
Calcium channel (nonspecified subtype) | Alpha-2 Adrenergic receptors (nonspecified subtype) | PTGIR | DGAT2 | TNNI2 | F10 | Guanylate cyclase (nonspecified subtype) | Skeletal muscle troponin | NOS3 | CES1 | G7422 | PDE5A | HTR2A | TNNT3 | P2RY12 | LIPC | HRH1 | Triacylglycerol Lipase (TG Lipase) (nonspecified subtype) | TXNRD1 | alpha1-Adrenoceptor (nonspecified subtype) | OLR1 | Nitric oxide synthase (NOS) (nonspecified subtype) | LIPE | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3 (PDE3) (nonspecified subtype) | Soluble guanylyl cyclase | AMP-activated protein kinase (AMPK) | Phosphodiesterase (nonspecified subtype) | ADRA2C | LIPG | EDNRA | TBXAS1 | Prostanoid Receptor (nonspecified subtype)

疾病靶点研报
Intermittent Claudication

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