Pneumoconiosis

About the Disease
Anthracosis, also known as black lung, is related to baritosis and bronchitis. An important gene associated with Anthracosis is CCL2 (C-C Motif Chemokine Ligand 2), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PAK Pathway. The drugs Pirfenidone and Antirheumatic Agents have been mentioned in the context of this disorder. Affiliated tissues include lung, lymph node and heart, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Common Targets
TGFB1 | MLPH | G7124 | Transforming growth factor beta (nonspecified subtype)

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