Situs Inversus

About the Disease
Dextrocardia with Situs Inversus, also known as situs inversus totalis, is related to ciliary dyskinesia, primary, 7 and ciliary dyskinesia, primary, 4. An important gene associated with Dextrocardia with Situs Inversus is PKD1L1 (Polycystin 1 Like 1, Transient Receptor Potential Channel Interacting), and among its related pathways/superpathways is Ciliopathies. The drugs Nitric Oxide and Bronchodilator Agents have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and spleen, and related phenotypes are growth/size/body region and embryo

Common Targets
MNS1 | CFAP53 | PKD1L1 | NME7 | DNAH9

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