Esophageal Carcinoma

About the Disease
Esophageal Cancer, also known as esophageal carcinoma, is related to esophagus squamous cell carcinoma and squamous cell carcinoma, and has symptoms including abdominal pain, constipation and coughing. An important gene associated with Esophageal Cancer is TGFBR2 (Transforming Growth Factor Beta Receptor 2), and among its related pathways/superpathways are Epithelial to mesenchymal transition in colorectal cancer and miRNAs involved in DNA damage response. The drugs Iron and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include esophagus, lymph node and lung, and related phenotypes are dysphagia and weight loss

Common Targets
CASZ1 | APC | FBXW7 | RASSF1 | ITGAM | AURKA | G472 | G1956 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | NFKB1 | ERCC5 | PDE4D | TUBB2B | MLH1 | MAP2K4 | DPYD | XPC | CDH13 | PADI4 | Integrin alphaMbeta2 (MAC-1) Receptor | CRABP1 | AKAP12 | G7015 | TSC1 | PKD1 | PDK1 | CYP2A6 | TFRC | ERCC1 | IL1RN | PKD2 | LILRB4 | CTAG1A | CYP2D6 | FAT4 | CYP2C19 | DNMT3A | FAT1 | PMS1 | BUB1B | LZTR1 | VIM | NPM1 | OPRM1 | CA1 | G5133 | MT1A | CSF1R | SOX17 | POLE | FLACC1 | RUNX3 | CEBPA | G3479 | G29126 | G5728 | IDH1 | MAOA | PMS2 | TTC6 | HSF1 | ING2 | ARID2 | DDR2 | G4851 | BRCA2 | PAK3 | MAP2K1 | CYP1A1 | KLLN | BLOC1S5-TXNDC5 | WEE1 | OGG1 | NFKBIA | SEMA5B | ROS1 | WRN | EEF1E1-BLOC1S5 | CD40 | ITGB2 | G1029 | FHIT | PLCE1 | PDGFRB | G142 | EPO | FOXA1 | PKHD1 | TET2 | EPHA3 | G4609 | MUC1 | PTCH1 | PRF1 | G999 | CSNK1A1 | GSTT1 | BLOC1S5 | TRIM44 | WEE2 | ERCC2 | CTDSPL | KMT2A | G2033 | FLT1 | G7157 | GHR | BMP6 | G2099 | RARB | CCNA1 | HNF1A | FGFR4 | RB1 | PIN1 | Tubulin | ZNF703 | CTAG1B | ACYP2 | TTLL5 | ERBB4 | TXNDC5 | FANCA | NELL1 | NF1 | RUNX1 | G4233 | PIK3CA | MIR146A | SDHA | G7124 | BRIP1 | SFRP1 | G2064 | G367 | G672 | FLT3 | XPA | MYCN | KMT2D | BMPR1A | GNAS | Integrin alphavbeta8 Receptor | CREBBP | GSTM1 | RET | TOP2A | H2BC5 | VHL | G5243 | ATR | CDKN1C | DENND1A | CYLD | CBLB | TFPI2 | PRKN | TAC1 | CYP2D7 | G238 | KDM5A | G596 | GRIN2B | CHEK2 | TNFRSF9 | IL23R | KDR | MSH2 | PIP5K1P1 | G10413 | XBP1 | XRCC1 | TUBB3 | DUSP2

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