Hyperbilirubinemia

About the Disease
Bilirubin Metabolic Disorder, also known as hyperbilirubinemia, is related to gilbert syndrome and crigler-najjar syndrome, type i, and has symptoms including icterus, polydipsia and muscle weakness. An important gene associated with Bilirubin Metabolic Disorder is UGT1A1 (UDP Glucuronosyltransferase Family 1 Member A1), and among its related pathways/superpathways are Metabolism and Metapathway biotransformation Phase I and II. The drugs Oxytocin and Ritonavir have been mentioned in the context of this disorder. Affiliated tissues include liver, bone marrow and breast.

Common Targets
UGT1A10 | UGT1A8 | UGT1A7 | BLVRA | ABCC2 | UGT1A4 | SLC19A1 | RFC1 | SLC22A16 | UGT1A6 | UGT1A9 | Heme Oxygenase (HO) (nonspecified subtype) | TCN2 | G5243 | CBS | UGT1A5 | MTHFR | Uncharacterized LOC102724946, transcript variant X3 | SLCO1B1 | UGT1A1 | SLCO1B3 | HMOX1 | NF-kappaB (NFkB) | UGT1A3 | CYP3A4

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