Epidermolysis Bullosa Simplex

About the Disease
Epidermolysis Bullosa Simplex, also known as ebs, is related to epidermolysis bullosa simplex 1b, generalized intermediate and epidermolysis bullosa simplex 1d, generalized, intermediate or severe, autosomal recessive. An important gene associated with Epidermolysis Bullosa Simplex is KRT5 (Keratin 5), and among its related pathways/superpathways are Nervous system development and Collagen chain trimerization. The drugs Erythromycin and Prilocaine have been mentioned in the context of this disorder. Affiliated tissues include skin, skeletal muscle and bone marrow, and related phenotypes are growth/size/body region and digestive/alimentary

Common Targets
DST | G2475 | PLEC | EXPH5 | KRT5 | LAMB3 | COL17A1 | LAMC2 | KRT14 | TGM5 | IL1B | ENPP1 | CCR5 | Proteasome Complex | CASP1 | NLRP3 Inflammasome | G114548 | KLHL24 | ITGB4 | CD19

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