Epidermolysis Bullosa Simplex

About the Disease
Epidermolysis Bullosa Simplex, also known as ebs, is related to epidermolysis bullosa simplex 1b, generalized intermediate and epidermolysis bullosa simplex 1d, generalized, intermediate or severe, autosomal recessive. An important gene associated with Epidermolysis Bullosa Simplex is KRT5 (Keratin 5), and among its related pathways/superpathways are Nervous system development and Collagen chain trimerization. The drugs Erythromycin and Prilocaine have been mentioned in the context of this disorder. Affiliated tissues include skin, skeletal muscle and bone marrow, and related phenotypes are growth/size/body region and digestive/alimentary

Common Targets
DST | G2475 | PLEC | EXPH5 | KRT5 | LAMB3 | COL17A1 | LAMC2 | KRT14 | TGM5 | IL1B | ENPP1 | CCR5 | Proteasome Complex | CASP1 | NLRP3 Inflammasome | G114548 | KLHL24 | ITGB4 | CD19

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Hamartoma | Barrett Esophagus | Antenatal Bartter Syndrome Type 1 | Pemphigus | Megaloblastic Anemia | Early Infantile Epileptic Encephalopathy 4 | Porphyria, Acute Intermittent | Cornelia De Lange Syndrome | Asphyxia Neonatorum | Juvenile Polyposis | Charcot-Marie-Tooth Disease, Type 6 | Cabezas Syndrome | Spondylocostal Dysostosis | Renal Tubular Acidosis | Congenital Afibrinogenemia | Colon Adenoma | Tardive Dyskinesia | Hypertension | Anovulation | Niemann-Pick Disease | Myeloid Leukemia | Phosphoglycerate Dehydrogenase Deficiency | Intracerebral Hemorrhage | Nicotine Dependence | Diabetic Neuropathy | Antisynthetase Syndrome | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Meckel-Gruber Syndrome | Spinocerebellar Ataxia Type 7 | Focal Facial Dermal Dysplasia | Cardiomyopathy, Hypertrophic | Glioblastoma Multiforme | Aspartylglycosaminuria | Arterial Tortuosity Syndrome | Charcot-Marie-Tooth Disease Type 2E | Apraxia | Congenital Hypofibrinogenemia | Progressive Familial 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