Disease

Plexiform Neurofibroma

About the Disease
Plexiform Neurofibroma, also known as neurofibroma, plexiform, is related to neurofibromatosis-noonan syndrome and neurofibroma. An important gene associated with Plexiform Neurofibroma is CDKN2B-AS1 (CDKN2B Antisense RNA 1), and among its related pathways/superpathways are ERK Signaling and GPCR Pathway. The drugs Sirolimus and Peginterferon alfa-2b have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, dorsal root ganglion and bone, and related phenotypes are Decreased viability and Decreased viability

Common Targets
CSF1R | RAC1 | LZTR1 | MAP2K1 | DDR2 | BCR | MAGEB2 | Mitogen-Activated Protein Kinase (nonspecified subtype) | G4233 | TEK | RAF1 | G5243 | FLT3 | KDR | DDR1 | RET | MAP2K2 | NF1 | ABL1 | KIT | GNAZ

疾病靶点研报
Plexiform Neurofibroma

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