Focal Facial Dermal Dysplasia

About the Disease
Focal Facial Dermal Dysplasia 3, Setleis Type, also known as setleis syndrome, is related to focal facial dermal dysplasia 1, brauer type and palmoplantar keratoderma, punctate type ia. An important gene associated with Focal Facial Dermal Dysplasia 3, Setleis Type is TWIST2 (Twist Family BHLH Transcription Factor 2). Affiliated tissues include skin and bone, and related phenotypes are low-set ears and prematurely aged appearance

Common Targets
TWIST2 | CYP26C1 | PORCN

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