Hypercalcemia

About the Disease
Hypercalcemia, Infantile, 1, also known as infantile hypercalcemia, is related to idiopathic infantile hypercalcemia and hypocalciuric hypercalcemia, familial, type i. An important gene associated with Hypercalcemia, Infantile, 1 is CYP24A1 (Cytochrome P450 Family 24 Subfamily A Member 1), and among its related pathways/superpathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors). The drugs Salmon calcitonin and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include bone, kidney and heart, and related phenotypes are nephrolithiasis and intellectual disability

Common Targets
PTHLH | AP2S1 | CSK | Integrin alphavbeta3 (vitronectin) receptor | ADAMTS5 | CTSL | Alcohol Dehydrogenase (nonspecified subtype) | CASR | Calcium channel (nonspecified subtype) | CYP24A1 | PTH | FDPS | PTPN4 | SLC34A1 | SLC34A3 | PTH1R | CTSK | CALCR | VDR

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