Chronic Mucocutaneous Candidiasis

About the Disease
Chronic Mucocutaneous Candidiasis, also known as candidiasis, chronic mucocutaneous, is related to candidiasis and immune deficiency disease, and has symptoms including scaling of skin lesions, thickening of nails and swollen periungal tissue. An important gene associated with Chronic Mucocutaneous Candidiasis is STAT1 (Signal Transducer And Activator Of Transcription 1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include skin, mucous membrane and nail due to t-cell defects, and related phenotypes are hyperkeratosis and abnormal fingernail morphology

Common Targets
GPR132 | THOC2 | TBC1D32 | THEMIS | G6772 | HHIPL1 | WNK3 | ATPSCKMT | POLA1 | USPL1 | MYBPC2 | TRAF3IP2

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