Poikiloderma With Neutropenia

About the Disease
Poikiloderma with Neutropenia, also known as poikiloderma with neutropenia, clericuzio type, is related to rothmund-thomson syndrome, type 2 and dyskeratosis congenita. An important gene associated with Poikiloderma with Neutropenia is USB1 (U6 SnRNA Biogenesis Phosphodiesterase 1). Affiliated tissues include skin, bone marrow and neutrophil, and related phenotypes are frontal bossing and splenomegaly

Common Targets
CSF3R | USB1

Note: If you'd like to get a target analysis report for Poikiloderma With Neutropenia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Poikiloderma With Neutropenia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Thyrotoxic Periodic Paralysis | Depression | Vulvovaginitis | Tietze Syndrome | Klippel-Feil Syndrome | Periodontitis | 3-hydroxy-3-methylglutaric Aciduria | Citrullinemia | Hyperuricemia | Emery-Dreifuss Muscular Dystrophy | Ellis-Van Creveld Syndrome | Neurocysticercosis | Genitopatellar Syndrome | Riboflavin Transporter Deficiency Neuronopathy | Restrictive Dermopathy | Meningitis | Porphyria, Variegate | Galloway-Mowat Syndrome | Spinocerebellar Ataxia Type 13 | Lymphoma, AIDS-related | Acrodysostosis | Agranulocytosis | Sleep Apnea, Obstructive | Danon Disease | Infantile Spasm | Cranioectodermal Dysplasia | Atrioventricular Septal Defect | Hyperbilirubinemia, Neonatal | Purpura | Shwachman-Bodian-Diamond Syndrome | Jaundice, Obstructive | Congenital Stromal Corneal Dystrophy | Reflex Epilepsy | Autonomic Nervous System Disorders | Osteoarthritis | Keratopathy | Precocious Puberty | Chronic Thromboembolic Pulmonary Hypertension | Birt-Hogg-Dube Syndrome | Panniculitis | Thromboembolism | Niemann-Pick Disease, Type C | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Acute Tubular Necrosis | Down Syndrome | Partington Syndrome | Autosomal Recessive Spastic Paraplegia Type 54 | Amish Infantile Epilepsy Syndrome | Myoclonic Epilepsy With Ragged Red Fibers | Acrodermatitis Enteropathica | Autism Spectrum Disorders | Alpha-mannosidosis | Wilson's Disease | Tyrosinemia Type 2 | Deafness, Dystonia, And Cerebral Hypomyelination | Benign Familial Neonatal Convulsions | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Chronic Neutrophilic Leukemia | Spinal Muscular Atrophy | Wagner Disease | Klinefelter Syndrome | Thin Basement Membrane Disease | Waardenburg Syndrome Type 4 | Trachoma | Schizotypal Personality Disorder | Osteoporosis | Pseudohypoparathyroidism Type 1A | Open-angle Glaucoma | Systemic Mastocytosis | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Metaphyseal Chondrodysplasia, Schmid Type | Spitz Nevus | Neuroblastoma | Tic Disorder | Dysthymia | Glycogen Storage Disease Type 0, Muscle | Prostatitis | Hypohidrotic Ectodermal Dysplasia, X-linked | Melanoma, Uveal | 3-methylglutaconic Aciduria Type IV | Follicular Dendritic Cell Sarcoma | Schnitzler Syndrome | Corneal Dystrophy And Perceptive Deafness | Schnyder Crystalline Corneal Dystrophy | Diabetic Encephalopathy | Spinocerebellar Ataxia Type 1 | CEDNIK Syndrome | Paraganglioma, Carotid Body | Protein S Deficiency | Transthyretin-related Amyloidosis | Polycystic Liver | Congenital Nystagmus | Patent Ductus Arteriosus | Placenta Previa | Huntington's Disease | Idiopathic Multicentric Castleman Disease | Progressive External Ophthalmoplegia | Congenital Disorders Of Glycosylation | Smoldering Myeloma | Microcephaly | Chediak-Higashi Syndrome | Angioedema | Olmsted Syndrome | Pulmonary Tuberculosis | 3-methylglutaconic Aciduria Type I | Charcot-Marie-Tooth Disease Type 4B1 | Osteogenesis Imperfecta Type III | MIRAGE Syndrome | Obsessive-compulsive Disorder | Congenital Disorders Of Glycosylation Type II | Vertigo | Hepatic Adenomatosis | Vitelliform Macular Dystrophy | Lymphoma, Follicular | Cardiofaciocutaneous Syndrome | Pseudomyxoma Peritonei | Encephalitis, Tick-borne | Takenouchi-Kosaki Syndrome | Vitamin B12 Deficiency | Sengers Syndrome | Autoimmune Disease | Hidradenitis | Pendred Syndrome | Epilepsy Of Infancy With Migrating Focal Seizures | Early Infantile Epileptic Encephalopathy | Lamellar Ichthyosis | Kabuki Syndrome | Pineoblastoma | Glomerulonephritis | Rhabdomyosarcoma, Alveolar | Charcot-Marie-Tooth Disease, Type 2 | Trimethylaminuria | Osteogenesis Imperfecta Type II | Primary Biliary Cholangitis | Hyper IgE Syndrome | Homocystinuria | Primary Carnitine Deficiency | Alpers Syndrome | Methylmalonic Aciduria And Homocystinuria, CblC Type | Eosinophilic Asthma | Gastritis | Coma | Empyema | Sepiapterin Reductase Deficiency | Shprintzen-Goldberg Syndrome | Absence Epilepsy | Withdrawal Syndrome | Hernia, Inguinal | Lymphopenia | Sickle Cell Anemia | Graft-versus-host Disease | Spondylocarpotarsal Synostosis Syndrome | Anorchia | Congenital Lipoid Adrenal Hyperplasia | Schizencephaly | Arthrogryposis | Currarino Syndrome | Coffin-Lowry Syndrome | Cryopyrin-associated Periodic Syndromes | Acute Lymphocytic Leukemia | Turner's Syndrome | Urofacial Syndrome | 3-methylglutaconic Aciduria | Iron Deficiency Anemia | Cholelithiasis | Ganglioneuroma | Encephalopathy | Dystonia-parkinsonism, X-linked | Knobloch Syndrome | Osteoglophonic Dysplasia | Ovarian Sex Cord-stromal Tumor | Hidradenitis Suppurativa | Glioma | Gitelman Syndrome | Ectopia Lentis, Isolated, Autosomal Recessive | Fahr Disease | DiGeorge Syndrome | Seborrheic Dermatitis | Hypertension, Pulmonary | Intermittent Explosive Disorder | Xeroderma Pigmentosum Variant Type | Obesity, Morbid | Hyperacusis | Amebiasis | Constipation | Congenital Dyserythropoietic Anemia | Neuronal Ceroid Lipofuscinosis | Duchenne Muscular Dystrophy | Cholangitis | Congenital Torticollis | Pulverulent Zonular Cataract | REM Sleep Behavior Disorder | Hypogammaglobulinemia | Rhinitis | Retinal Coloboma | Major Depression | Hydrolethalus Syndrome | Spitzoid Melanoma | Leber Hereditary Optic Neuropathy | Retinitis Pigmentosa 3 | Cataplexy | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Fanconi Syndrome | Thrombocytopenia | Larsen Syndrome | Cataract | Seizures | Kernicterus | Posterior Polar Cataract | Cranial Nerve Disease | Iron Metabolism Disorders | Hypolipoproteinemia | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | VEXAS Syndrome | Mucolipidosis | Celiac Disease | Renal Tubular Dysgenesis | Osteochondrosis | Oguchi Disease-2 | Cholestasis | Johanson-Blizzard Syndrome | Cat Eye Syndrome | Anorectal Malformations | Bulimia Nervosa | Hypokalemia | Fetal And Neonatal Alloimmune Thrombocytopenia | Amelogenesis Imperfecta | Hypoalbuminemia | Enlarged Vestibular Aqueduct | Restless Legs Syndrome | Supravalvular Aortic Stenosis | Familial Cerebral Amyloid Angiopathy | Primary Hyperoxaluria Type 3 | Paraganglioma | Seizures-scoliosis-macrocephaly Syndrome | Neuromuscular Disorders | X-linked Myotubular Myopathy | Metanephric Adenoma | Retinoschisis | Hepatorenal Syndrome | Schwannomatosis | Renal Hypomagnesemia 3 | Cheilitis | Globozoospermia | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Neurocutaneous Melanocytosis | Chondromyxoid Fibroma | Cherubism | Epidermolytic Ichthyosis, Annular | Cutis Laxa | Chudley-McCullough Syndrome | Ophthalmoplegia | Giant Axonal Neuropathy | Leukemia-lymphoma, Adult T-cell | Thrombosis | Infertility | Nemaline Myopathy 8 | Nanophthalmos | Palmoplantar Keratoderma | Epidermolysis Bullosa Acquisita | Esophageal Carcinoma | Priapism | Prader-Willi Syndrome | Heimler Syndrome | Fetal Akinesia Deformation Sequence | Myelomeningocele | Waardenburg Syndrome | Silicosis | Congenital Hereditary Endothelial Dystrophy Type I | Pemphigus Foliaceus | Pituitary Disorders | Keratoconus | Evans Syndrome | Cardiac Arrest | Congenital Muscular Dystrophy | Purpura, Thrombotic Thrombocytopenic | Thrombasthenia | Spinal Muscular Atrophy Type 3 | Fukuyama Congenital Muscular Dystrophy | Primary Pigmented Nodular Adrenocortical Disease | Chloridorrhea, Congenital | Vitreoretinal Degeneration, Snowflake Type | Stomatitis | Pheochromocytoma | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Eiken Syndrome | Varices | Thalassemia, Beta | Cystitis, Interstitial | Familial Male-limited Precocious Puberty | Gastritis, Atrophic | Hepatitis C, Chronic | Arts Syndrome | Carcinoma, Transitional Cell | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Cockayne Syndrome | Progressive Osseous Heteroplasia | Thanatophoric Dysplasia Type 1 | Juvenile Myoclonic Epilepsy | Kearns-Sayre Syndrome | Chromosome 16p11.2 Deletion Syndrome | Aromatic L-amino Acid Decarboxylase Deficiency | Multiple Sclerosis | Polyarteritis Nodosa | Colon Adenoma | Adenosine Deaminase Deficiency | Chondrosarcoma | Progressive Myoclonic Epilepsy | Ischemia | Trichothiodystrophy | Chronic Myeloid Leukemia | Presbyopia | Osteopetrosis | Acute Generalized Exanthematous Pustulosis | Rothmund-Thomson Syndrome | Cholesteryl Ester Storage Disease | Pigment Dispersion Syndrome | Hypospadias | Facioscapulohumeral Muscular Dystrophy Type 1 | Xeroderma Pigmentosum | Nephronophthisis | Anovulation | Camurati-Engelmann Disease | LRBA Deficiency | HELLP Syndrome | Glycogen Storage Disease Type 4 | Rolandic Epilepsy | Hydrocephalus, Normal Pressure | Lennox-Gastaut Syndrome | Ganglioglioma | Keloid | Skin Carcinoma | Short-chain Acyl-CoA Dehydrogenase Deficiency | Dermatitis | IMAGe Syndrome | Osteosclerosis | Charcot-Marie-Tooth Disease Type 3 | Agnathia-Otocephaly Complex | Epithelioid Hemangioma | Diabetes Type 1 | Sarcoma | Keratitis-ichthyosis-deafness Syndrome | Infertility, Male | Kawasaki Disease | Astrocytoma, Anaplastic | Histoplasmosis | Familial Hyperaldosteronism | B-cell Prolymphocytic Leukemia | Malaria, Cerebral | Diabetes Gestational | Proctitis | Tetanus | Pulmonary Veno-occlusive Disease | Waardenburg Syndrome Type 4A | Hypertrophy | NDH Syndrome | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Neurodermatitis | HUPRA Syndrome | ACTH-independent Macronodular Adrenal Hyperplasia | Paracoccidioidomycosis | Muckle-Wells Syndrome | Inflammatory Myopathy | Parkinson Disease 6, Autosomal Recessive Early-onset | Hereditary Coproporphyria | Leukocyte Adhesion Deficiency Type 1 | Hypervalinemia | Transient Bullous Dermolysis Of The Newborn | Norrie Disease | Congenital Dyserythropoietic Anemia Type 4 | Galactosemia | Focal Dermal Hypoplasia | Botulism | Imerslund-Grasbeck Syndrome | Ependymoma | Chondrodysplasia Punctata 1, X-linked Recessive | Specific Granule Deficiency | Hyperuricemic Nephropathy, Familial Juvenile | Cornelia De Lange Syndrome | Zellweger Syndrome | Borjeson-Forssman-Lehmann Syndrome | Congenital Hereditary Endothelial Dystrophy Type II | Asplenia | Spondyloarthritis | Loeys-Dietz Syndrome Type 4 | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Conn Syndrome | Hypersomnia | Epithelial-myoepithelial Carcinoma | Fabry's Disease | Hereditary Spherocytosis | Oligospermia | Pre-eclampsia | Primrose Syndrome | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Congestive Heart Failure | Hodgkin Lymphoma | Osmotic Demyelination Syndrome | Ghosal Syndrome