Disease

Osmotic Demyelination Syndrome

About the Disease
Central Pontine Myelinolysis, also known as myelinolysis, central pontine, is related to alcohol use disorder and alcohol dependence, and has symptoms including acute paralysis, dysphagia and dysarthria. An important gene associated with Central Pontine Myelinolysis is MBP (Myelin Basic Protein), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Neuroscience. Affiliated tissues include pons, brain and liver, and related phenotypes are Negative genetic interaction between PTEN-/- and PTEN+/+ and nervous system

Common Targets
ESR2 | G2099

疾病靶点研报
Osmotic Demyelination Syndrome

Note: If you'd like to get a target analysis report for Osmotic Demyelination Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Osmotic Demyelination Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Ectrodactyly | Haim-Munk Syndrome | Hemosiderosis | Hemoglobinopathies | Anorexia Nervosa | Pulmonary Vein Stenosis | Geleophysic Dysplasia | Intestinal Obstruction | Hyperinsulinemia | Chronic Myeloid Leukemia | Hemorrhoids | H Syndrome | Intestinal Hypomagnesemia 1 | Hashimoto Thyroiditis | Primary Erythromelalgia | Atrial Septal Defect | Primary Progressive Nonfluent Aphasia | Familial Exudative Vitreoretinopathy | Chorioretinitis | Long QT Syndrome Type 1 | Smith-Magenis Syndrome | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Neuronal Ceroid Lipofuscinosis | Hypertension, Portal | Renal Hypomagnesemia 3 | Lewy Body Dementia | Silver-Russell Syndrome | Norrie Disease | Purpura, Thrombotic Thrombocytopenic | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Creatine Deficiency Syndrome | Specific Granule Deficiency | Alveolar Capillary Dysplasia | Hermansky-Pudlak Syndrome | Spinocerebellar Ataxia Type 12 | Esophageal Motility Disorders | Erythematotelangiectatic Rosacea | Angiosarcoma Of The Breast | Congenital Generalized Lipodystrophy | Beta-Propeller Protein-associated Neurodegeneration | Carpal Tunnel Syndrome | Anxiety Disorders | Mabry Syndrome | Exostoses | Patent Foramen Ovale | Lactose Intolerance | Charcot-Marie-Tooth Disease, Type 2C | Spinal And Bulbar Muscular Atrophy | Alagille Syndrome | Familial Isolated Hyperparathyroidism | Polycystic Kidney, Autosomal Dominant | Necrotizing Autoimmune Myopathy | Optic Nerve Diseases | Coffin-Lowry Syndrome | Iron Deficiency Anemia | POEMS Syndrome | Achondrogenesis | Lymphoma, Mantle Cell | Hereditary Folate Malabsorption | Parvovirus B19 Infection | Impetigo | Meckel-Gruber Syndrome | Interstitial Lung Diseases | Behcet's Disease | Stroke, Hemorrhagic | Neurofibromatosis Type 2 | Congenital Hereditary Endothelial Dystrophy Type II | Fundus Albipunctatus | Kidney Stones | Uremic Pruritus | Granular Corneal Dystrophy | Muckle-Wells Syndrome | Dentinogenesis Imperfecta | Charcot-Marie-Tooth Disease Type 2E | Pompe Disease | Pneumonia, Viral | Intestinal Tuberculosis | Keratoconus | Otitis Externa | Hypercalcemia | Spina Bifida | Seminoma | Genee-Wiedemann Syndrome | Smith-Kingsmore Syndrome | Trichomegaly | Tyrosinemia Type 2 | Tietze Syndrome | Ocular Hypertension | Benign Recurrent Intrahepatic Cholestasis 1 | Macrophagic Myofasciitis | Hypotonia-cystinuria Syndrome | Uveitis, Anterior | Apert Syndrome | Anuria | Hyperbilirubinemia | Cerebral Cavernous Malformations | Infertility | Polycythemia Vera | McKusick Type Metaphyseal Chondrodysplasia | Left Ventricular Noncompaction | Partington Syndrome | Reye Syndrome | Pancytopenia | Leigh Syndrome | Osteopathia Striata With Cranial Sclerosis | Episodic Ataxia Type 2 | Gout | Hepatitis | Frank-ter Haar Syndrome | Rotor Syndrome | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Paronychia | Echinococcosis | Shock, Cardiogenic | Congenital Bilateral Absence Of Vas Deferens | N-acetylglutamate Synthase Deficiency | Pulmonary Stenosis | Cutaneous Lupus Erythematosus | Osteogenesis Imperfecta Type VI | Wiskott-Aldrich Syndrome | Intellectual Disability, Autosomal Dominant 5 | Wolff-Parkinson-White Syndrome | Encephalopathy, Hepatic | Chromosome 9q34.3 Deletion Syndrome | Keratoconjunctivitis | Glomerulonephritis, Membranous | Carbohydrate Metabolism Disorders | Inflammatory Joint Disease | Vertebrobasilar Insufficiency | Amyotrophic Lateral Sclerosis | Cholera | Chediak-Higashi Syndrome | Methemoglobinemia | Epidermodysplasia Verruciformis | Sarcoidosis | Cirrhosis | Strabismus | Large Granular Lymphocytic Leukemia | DOCK8 Immunodeficiency Syndrome | Cancer, Prostate | Panniculitis | Shwachman-Bodian-Diamond Syndrome | Mood Disorder | Bietti Crystalline Dystrophy | Mitochondrial DNA Depletion Syndrome 13 | Smith-Lemli-Opitz Syndrome | Pemphigus Vulgaris | Nail-Patella Syndrome | Spinocerebellar Ataxia Type 17 | Thrombophlebitis | Polycystic Liver | Infectious Diarrhea | Endometrial Hyperplasia | Exocrine Pancreatic Insufficiency | Charcot-Marie-Tooth Disease Type 4 | Beckwith-Wiedemann Syndrome | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | CHOPS Syndrome | Hemolytic Uremic Syndrome | Lymphoma | Heimler Syndrome | Precocious Puberty | Postpoliomyelitis Syndrome | Paraganglioma | Anemia | Bicuspid Aortic Valve | Thrombocytopenia | Osteoporosis-pseudoglioma Syndrome | Cabezas Syndrome | Chanarin-Dorfman Syndrome | Blepharoconjunctivitis | Anorectal Fistula | Cardiomyopathy, Hypertrophic | Chronic Granulomatous Disease, X-linked | Diamond-Blackfan Anemia | Rhabdomyosarcoma, Alveolar | Proximal Symphalangism | Spinocerebellar Ataxia Type 16 | Epicondylitis | Pain | Thyroid Hormone Resistance | Sickle Cell Anemia | Corneal Edema | Cardiomyopathy, Dilated, 1L | Schwartz-Jampel-Aberfeld Syndrome | Abetalipoproteinemia | Gerodermia Osteodysplastica | Okihiro Syndrome | Li-Fraumeni Syndrome | Cole-Carpenter Syndrome | Focal Dermal Hypoplasia | Osteogenesis Imperfecta Type V | Gastric Atrophy | Woodhouse-Sakati Syndrome | Sleep Disorder | Holoprosencephaly | Fucosidosis | Deafness, Dystonia, And Cerebral Hypomyelination | Dystrophy, Cone-rod | Agoraphobia | Choriocarcinoma | Bardet-Biedl Syndrome | Pseudo-pseudohypoparathyroidism | Primary Carnitine Deficiency | Encephalopathy, Ethylmalonic | Tylosis With Esophageal Cancer | Carcinoid Syndrome | Alopecia | Allan-Herndon-Dudley Syndrome | Chondroma | Spondylo-ocular Syndrome | Rolandic Epilepsy | Knobloch Syndrome | Schwannoma | Teratozoospermia | Osteogenesis Imperfecta | Cyclic Vomiting Syndrome | Iron Overload | DICER1 Syndrome | Liver Failure, Acute Infantile | Metachromatic Leukodystrophy | Inflammatory Linear Verrucous Epidermal Nevus | Aplasia Cutis Congenita | Tularemia | Pure Red Cell Aplasia | Carbamoyl Phosphate Synthetase I Deficiency | Globozoospermia | Ganglioglioma | Senior-Loken Syndrome | Vitreoretinopathy, Proliferative | Chronic Idiopathic Myelofibrosis | Glycogen Storage Disease Type 0, Muscle | Asphyxia Neonatorum | Acromesomelic Dysplasia | Spinocerebellar Ataxia Type 21 | Fuchs Dystrophy | Endometritis | Ghosal Syndrome | IMAGe Syndrome | Optic Nerve Hypoplasia, Bilateral | Optic Neuropathy, Anterior Ischemic | Nijmegen Breakage Syndrome | Keratopathy | Neurofibromatosis Type 1 | Borjeson-Forssman-Lehmann Syndrome | Hemophilia | Multicystic Renal Dysplasia | Dwarfism | Axenfeld-Rieger Syndrome | Multiple Sclerosis, Chronic Progressive | Thyroiditis | Rhizomelic Chondrodysplasia Punctata | Lymphangiomatosis | Retinal Vasculitis | Sweet Syndrome | Chorea-acanthocytosis | Klinefelter Syndrome | Ocular Albinism Type 1 | Diabetes Insipidus | Niemann-Pick Disease, Type B | Carcinoma, Merkel Cell | Necrobiosis Lipoidica | Carcinoma, Small Cell | Sleep Apnea, Central | Microcephaly | Osteochondrosis | Chromosome 5q Deletion Syndrome | Anovulation | C3 Glomerulonephritis | Spinocerebellar Ataxia Type 20 | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Panic Disorder | Dent Disease | Cushing Syndrome | Ectodermal Dysplasia | Neuroma | Granuloma Annulare | Long QT Syndrome Type 2 | Whipple's Disease | Photosensitivity | Hypoplastic Left Heart Syndrome | Osmotic Demyelination Syndrome | Eczema | Hyperphenylalaninemia | Coronary Restenosis | Otopalatodigital Syndrome Type 2 | Early Infantile Epileptic Encephalopathy 4 | X-linked Myotubular Myopathy | Congenital Poikiloderma | Colon Adenoma | Skin Fragility-woolly Hair Syndrome | Congenital Heart Block | Nutrition Disorders | Infantile Spasm | Gynecomastia | Cohen Syndrome | Familial Digital Arthropathy-brachydactyly | Encephalitis, Tick-borne | Epilepsy, Generalized | Papillorenal Syndrome | Brooke-Spiegler Syndrome | Early Infantile Epileptic Encephalopathy 1 | Tinea | Sarcoma | Retinoschisis | Takotsubo Cardiomyopathy | GM2-gangliosidosis AB Variant | Acute Lymphocytic Leukemia | Seizures-scoliosis-macrocephaly Syndrome | Skin Papilloma | Hidradenitis | Angioedema, Hereditary | Non-Langerhans Cell Histiocytosis | Lissencephaly 2 | Poirier-Bienvenu Neurodevelopmental Syndrome | Ovarian Sex Cord-stromal Tumor | Congenital Nephrotic Syndrome | Acute Myeloid Leukemia | Papilledema | Polymyositis | Kleine-Levin Syndrome | Avian Influenza | Urticaria | Nasodigitoacoustic Syndrome | Dementia | Progressive Familial Intrahepatic Cholestasis Type 3 | Brugada Syndrome 1 | Pigment Dispersion Syndrome | Aromatic L-amino Acid Decarboxylase Deficiency | Angioedema | Primary Hyperoxaluria Type 1 | Temporal Lobe Epilepsy | Hereditary Xerocytosis | Sarcomatoid Carcinoma Of The Lung | Benign Familial Infantile Seizures | Hypotrichosis | Optic Atrophy 2 | Renal Dysplasia | Gastroenteritis | Measles | SAPHO Syndrome | Erythropoietic Protoporphyria | Menetrier Disease | Guillain-Barre Syndrome | Wiedemann-Steiner Syndrome | Myelitis | Persistent Mullerian Duct Syndrome | Raynaud Phenomenon | Thin Basement Membrane Disease | Waardenburg Syndrome Type 2A | Methylmalonic Aciduria And Homocystinuria, CblC Type | Spinocerebellar Ataxia Type 2 | Acrodysostosis | Fibronectin Glomerulopathy | Focal Cortical Dysplasia Type 2 | Cholestasis, Intrahepatic | Alzheimer Disease, Late Onset | Epidermolysis Bullosa Simplex, Localized | Cutaneous T-cell Lymphoma | TARP Syndrome | Osteonecrosis Of The Jaw | Hemorrhage | Palsy, Cerebral | CDKL5 Deficiency Disorder | Schizophrenia | Rhabdomyosarcoma | Paget's Disease Of The Breast | Scapuloperoneal Myopathy, X-linked Dominant | Lymphedema | Blue Rubber Bleb Nevus Syndrome | Polycystic Ovary Syndrome | Aldosterone Synthase Deficiency | Lipid Storage Myopathy | Ventricular Septal Defect | Hypobetalipoproteinemias | Parapsoriasis | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Spastic Paraplegia Type 7 | Lathosterolosis | Mixed Connective Tissue Disease | Diffuse Mesangial Sclerosis | Common Cold | Glutathione Synthetase Deficiency | Vitamin A Deficiency | Congenital Myasthenic Syndrome | Kaposi Sarcoma | Multiple Hamartoma Syndrome | 3C Syndrome | Hypertrophy | Poretti-Boltshauser Syndrome | Corneal Dystrophy | Epidermolysis Bullosa Acquisita | Mitochondrial Disease | Erectile Dysfunction | Nephrocalcinosis | Lymphoma, B-cell | Hodgkin Lymphoma | Hypodontia | Arthrogryposis