Hemosiderosis

About the Disease
Rare Hereditary Hemochromatosis, also known as iron overload, is related to hemochromatosis, type 5 and iron overload in africa. An important gene associated with Rare Hereditary Hemochromatosis is HFE (Homeostatic Iron Regulator), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Insulin receptor recycling. The drugs Orange and Deferasirox have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and bone marrow, and related phenotypes are liver/biliary system and homeostasis/metabolism

Common Targets
APP | HNF4A | APOE

Note: If you'd like to get a target analysis report for Hemosiderosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hemosiderosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Cutis Laxa | AIDS | Lafora Disease | Nestor-Guillermo Progeria Syndrome | Diabetes | Malnutrition | Microcephaly | Metanephric Adenoma | Vici Syndrome | Keratosis | Sick Sinus Syndrome 1 | Graves Disease | Nephrosclerosis | DICER1 Syndrome | Generalized Epilepsy With Febrile Seizures Plus | Hepatitis | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Malignant Fibrous Histiocytoma | Cancer, Colon | Hyperprolactinemia | Central Retinal Artery Occlusion | Agammaglobulinemia | Hypoalbuminemia | Autosomal Recessive Spastic Paraplegia Type 35 | Osteochondroma | Juvenile Myoclonic Epilepsy | Angelman Syndrome | Sialidosis Type I | Diabetes Gestational | Low Tension Glaucoma | Acute Generalized Exanthematous Pustulosis | Osteopetrosis | Epidermodysplasia Verruciformis | Erythrokeratodermia Variabilis | Congenital Heart Block | Proteus Syndrome | Charcot-Marie-Tooth Disease, Type 2C | Ophthalmoplegia | Pancreatitis | Pupil Disorders | Leber Congenital Amaurosis | Mohr-Tranebjaerg Syndrome | Keratocystic Odontogenic Tumor | Dysplastic Nevus | Hairy Cell Leukemia | Irritable Bowel Syndrome | Ventricular Septal Defect | Lennox-Gastaut Syndrome | Inflammatory Bowel Disease | Echinococcosis | Congestive Heart Failure | Nemaline Myopathy | Meleda Disease | Motor Neuron Diseases | Platelet Disorders | X-linked Myotubular Myopathy | Narcolepsy | Pyruvate Kinase Deficiency | Polyomavirus Nephropathy | Hereditary Xerocytosis | DOCK8 Immunodeficiency Syndrome | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Central Pain Syndrome | Sengers Syndrome | Macular Corneal Dystrophy | Adenoma, Pleomorphic | Ichthyosis Bullosa Of Siemens | Toxic Epidermal Necrolysis | Cardiac Arrest | Glycogen Storage Disease Type 1 | Charcot-Marie-Tooth Disease Type 4B1 | Schwannoma | Dubin-Johnson Syndrome | Alzheimer Disease, Late Onset | Familial Retinal Arterial Macroaneurysm | Osteonecrosis | Fascioliasis | Urofacial Syndrome | Renal Tubular Dysgenesis | Fraser Syndrome | Dementia | Hypereosinophilic Syndrome | Hypohidrotic Ectodermal Dysplasia | Heroin Dependence | Metatropic Dysplasia | Persistent Hyperplastic Primary Vitreous | Cholangitis | Stroke | Chromosome 17q21.31 Deletion Syndrome | Lymphoma, Follicular | Macrodactyly | LRBA Deficiency | Schwartz-Jampel-Aberfeld Syndrome | Hepatic Steatosis | Pathological Gambling | Chondrodysplasia Punctata 2, X-linked Dominant | Dwarfism | Myelomeningocele | Colorectal Adenoma | Osteogenesis Imperfecta Type VI | Hypertriglyceridemia | Infectious Diarrhea | Pendred Syndrome | Transient Bullous Dermolysis Of The Newborn | Corneal Edema | Usher Syndrome Type II | Haim-Munk Syndrome | Wiedemann-Steiner Syndrome | Trichomegaly | Primary Progressive Aphasia | Familial Advanced Sleep Phase Syndrome | Weill-Marchesani Syndrome | Ovarian Hyperstimulation Syndrome | Hepatorenal Syndrome | Ataxia-ocular Apraxia 2 | Chronic Myeloid Leukemia | Nail-Patella Syndrome | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Osteoglophonic Dysplasia | Placenta Previa | Retinal Vasculitis | Meckel-Gruber Syndrome | Neuropathy | Osteogenesis Imperfecta Type IV | Perivascular Epithelioid Cell Tumor | Vitelliform Macular Dystrophy | Ureteropelvic Junction Obstruction | Stroke, Ischemic | Best Macular Dystrophy | Anal Fissure | Tyrosine Hydroxylase Deficiency | T-cell Prolymphocytic Leukemia | Pyruvate Decarboxylase Deficiency | Gestational Trophoblastic Disease | Left Ventricular Noncompaction | Rubinstein-Taybi Syndrome | Benign Familial Neonatal Convulsions | Donnai-Barrow Syndrome | Frontometaphyseal Dysplasia | Frontotemporal Dementia | Dengue Hemorrhagic Fever | Waardenburg Syndrome | Osteoporosis-pseudoglioma Syndrome | Thanatophoric Dysplasia | Thromboembolism | Jawad Syndrome | Myofibromatosis | Rothmund-Thomson Syndrome | Tracheal Disorders | Metaphyseal Chondrodysplasia, Schmid Type | Otitis Media | Pyloric Stenosis, Infantile Hypertrophic | Kidney Stones | Cholecystitis | Exfoliative Dermatitis | Vertebrobasilar Insufficiency | Polycythemia Vera | Vitamin A Deficiency | Blepharoconjunctivitis | Keratosis, Seborrheic | Chitayat Syndrome | Pseudohermaphroditism | Gastrointestinal Disorders | Glomerulonephritis | Holt-Oram Syndrome | Spondylosis | Progressive Familial Intrahepatic Cholestasis | Arterial Tortuosity Syndrome | Granular Corneal Dystrophy | Multiple Sclerosis | GM2-gangliosidosis AB Variant | Atrial Septal Defect | Glucagonoma | COACH Syndrome | Juvenile Polyposis | Heavy Chain Disease | Inflammatory Myofibroblastic Tumor | Chronic Thromboembolic Pulmonary Hypertension | Congenital Sodium Diarrhea | Chorioretinitis | Metabolic Syndrome | Meesmann Corneal Dystrophy | Usher Syndrome Type I | Kearns-Sayre Syndrome | Myoclonus | Goiter | Pyelonephritis | Epidermolysis Bullosa Acquisita | Nutrition Disorders | Corneal Dystrophies, Hereditary | Mitochondrial Encephalomyopathy | Stargardt Disease | Cornelia De Lange Syndrome | Carbonic Anhydrase VA Deficiency | Cerebellar Ataxia, Cayman Type | Combined Deficiency Of Factor V And Factor VIII | Dermatofibrosarcoma | Optic Nerve Hypoplasia, Bilateral | Autoimmune Polyendocrinopathy Syndrome Type I | Spondyloepiphyseal Dysplasia Tarda, X-linked | Carbamoyl Phosphate Synthetase I Deficiency | Johanson-Blizzard Syndrome | Palsy, Cerebral | Asphyxia Neonatorum | Carcinoma, Transitional Cell | Rheumatic Heart Disease | Congenital Bile Acid Synthesis Defect | Leber Hereditary Optic Neuropathy | Myhre Syndrome | Endometriosis | Paraplegia | Pulmonary Alveolar Microlithiasis | Gray Platelet Syndrome | Creatine Deficiency Syndrome | Angina Pectoris | Systemic Mastocytosis | Familial Episodic Pain Syndrome | Corneal Dystrophy And Perceptive Deafness | Osteosarcoma | Early Infantile Epileptic Encephalopathy | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Autosomal Recessive Spastic Paraplegia Type 54 | Congenital Dyserythropoietic Anemia Type 4 | Acute Leukemia | Basan Syndrome | Trichuriasis | Schnyder Crystalline Corneal Dystrophy | Scleroderma | Vascular Calcification | Crouzon Syndrome With Acanthosis Nigricans | Smith-Kingsmore Syndrome | Primary Sclerosing Cholangitis | Pemphigoid | Primary Carnitine Deficiency | Pyruvate Dehydrogenase Deficiency | Fahr Disease | Usher Syndrome Type IIC | CEDNIK Syndrome | Conduct Disorder | Transthyretin-related Amyloidosis | Ependymoma | Cancer, Kidney | Familial Hypertrophic Cardiomyopathy | Hepatitis, Alcoholic | Dysferlinopathy | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Isobutyryl-CoA Dehydrogenase Deficiency | Huntington's Disease-like 2 | Atopic Dermatitis | Rhabdomyosarcoma | Brenner Tumor | Polycythemia | Canavan Disease | Oculocutaneous Albinism Type 1 | Carcinoma In Situ | Pulmonary Alveolar Proteinosis | Allergic Contact Dermatitis | DRESS Syndrome | Conjunctivitis, Allergic | Stuttering | Gyrate Atrophy Of The Choroid And Retina | Nephrotic Syndrome Type 1 | Purpura | Acromegaly | Sarcoidosis, Pulmonary | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Odonto-onycho-dermal Dysplasia | Tendinopathy | Speech Disorders | Multifocal Motor Neuropathy | Zygomycosis | Woodhouse-Sakati Syndrome | Pulmonary Vein Stenosis | Basal Ganglia Disease | Adenosine Deaminase 2 Deficiency | Autoimmune Autonomic Ganglionopathy | Myoclonus-dystonia Syndrome | Gallstones | Congenital Dyserythropoietic Anemia | Glycogen Storage Disease Type 1b | Ichthyosis | Coronary Artery Disease | Otopalatodigital Syndrome Type 2 | Hidradenitis | Hypoparathyroidism | Pure Red Cell Aplasia | Multiple Hamartoma Syndrome | VACTERL Association | Dementia, Vascular | Centronuclear Myopathy | Congenital Hemolytic Anemia | Aarskog-Scott Syndrome | Congenital Afibrinogenemia | Lymphomatoid Granulomatosis | Ulcerative Colitis | Glioblastoma Multiforme | Chronic Neutrophilic Leukemia | Corneal Dystrophy | Mood Disorder | Hereditary Elliptocytosis | Reflex Epilepsy | Spinocerebellar Ataxia Type 2 | Hypoglycemia | 3-methylglutaconic Aciduria | Hyperbilirubinemia | Parkinson Disease 6, Autosomal Recessive Early-onset | Neurocutaneous Syndromes | Pantothenate Kinase-associated Neurodegeneration | Gastritis | Mitochondrial Cytopathy | Asplenia | Ghosal Syndrome | Primary Pigmented Nodular Adrenocortical Disease | Microcephalic Primordial Dwarfism | Astrocytoma, Anaplastic | Muir-Torre Syndrome | Parkinson's Disease | Gastroenteritis | Pelvic Inflammatory Disease | Pemphigus | Trismus-pseudocamptodactyly Syndrome | Hashimoto Thyroiditis | Tic Disorder | Melanoma, Uveal | Obsessive-compulsive Disorder | Congenital Myopathy | Small Lymphocytic Lymphoma | Hoyeraal-Hreidarsson Syndrome | Spinocerebellar Ataxia Type 10 | Monilethrix | Cutaneous Angiosarcoma | Spinocerebellar Ataxia Type 14 | Pontocerebellar Hypoplasia Type 2 | Common Variable Immunodeficiency | Schuurs-Hoeijmakers Syndrome | Milk Allergy | Stickler Syndrome | Spastic Paraplegia Type 7 | Marfan Syndrome | Juvenile Hyaline Fibromatosis | Hyperbilirubinemia, Neonatal | ACTH-independent Macronodular Adrenal Hyperplasia | Renal Medullary Carcinoma | Gastritis, Atrophic | Chondroma | Hypokalemic Periodic Paralysis | Juvenile Myelomonocytic Leukemia | Dysthymia | Erythromelalgia | Varicocele | Hepatitis B, Chronic | Fowler's Syndrome | Uremic Pruritus | Benign Familial Pemphigus | Viral Meningitis | Reticular Dysgenesis | Diarrhea | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Cold-induced Sweating Syndrome | Castleman Disease | Perry Syndrome | Temtamy Preaxial Brachydactyly Syndrome | Glomerulonephritis, Membranous | Pseudoachondroplasia | Cholelithiasis | Acrocallosal Syndrome | Fibromyalgia | Alopecia | Hepatitis C, Chronic | Mucolipidosis Type II | Endometrial Hyperplasia | Delayed Sleep Phase Syndrome | Glycogen Storage Disease Type 5 | Atelosteogenesis Type 2 | Shock, Cardiogenic | Autoimmune Polyendocrine Syndrome | Silver-Russell Syndrome | Lipodystrophy | Martsolf Syndrome | Pachyonychia Congenita | Gardner Syndrome | Xeroderma Pigmentosum Variant Type | Ischemia | Crohn's Disease | Peeling Skin Syndrome Type B | Hemangioblastoma | Fibromuscular Dysplasia | Muscle Wasting | Heterotopic Ossification | Hypercholesterolemia, Familial | X-linked Acrogigantism | Polycystic Kidney, Autosomal Recessive | Keratitis | Tibial Muscular Dystrophy | Generalized Epilepsy And Paroxysmal Dyskinesia | Intermittent Claudication | Glanzmann Thrombasthenia | Meconium Ileus | Oligoastrocytoma | Ameloblastoma