Fraser Syndrome

About the Disease
Fraser Syndrome 1, also known as fraser syndrome, is related to branchiootorenal syndrome and branchiootorenal syndrome 1. An important gene associated with Fraser Syndrome 1 is FRAS1 (Fraser Extracellular Matrix Complex Subunit 1), and among its related pathways/superpathways are Phospholipase-C Pathway and Primary focal segmental glomerulosclerosis (FSGS). Affiliated tissues include eye, kidney and skin, and related phenotypes are blindness and renal hypoplasia

Common Targets
FRAS1 | GRIP1 | FREM2

Note: If you'd like to get a target analysis report for Fraser Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Fraser Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Tendinitis | Fuchs Dystrophy | Brooke-Spiegler Syndrome | Keratosis, Seborrheic | Dyggve-Melchior-Clausen Disease | Amish Infantile Epilepsy Syndrome | Encephalocele | Carcinoma In Situ | Hereditary Sensory And Autonomic Neuropathy | Renal Hypouricemia | Otitis Externa | Amelogenesis Imperfecta | Alpers Syndrome | Familial Dysautonomia | Wiedemann-Steiner Syndrome | Chorea | Spinocerebellar Ataxia Type 28 | Trichuriasis | Cardiospondylocarpofacial Syndrome | Familial Thoracic Aortic Aneurysm | Myocarditis | Kindler Syndrome | Progressive Familial Intrahepatic Cholestasis Type 2 | Carcinoma, Signet Ring Cell | Histiocytosis | Pancreatitis | Cousin Syndrome | Diabetes | Diffuse Palmoplantar Keratoderma | Language Disorders | Heterotaxy | Congenital Dyserythropoietic Anemia Type 4 | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Hyperprolactinemia | Hypercalcemia | Ectopia Lentis, Isolated, Autosomal Recessive | Sulfite Oxidase Deficiency | Retinoblastoma | Dwarfism | Iron Overload | Intestinal Tuberculosis | Hemangioma | Bone Giant Cell Tumor | Retinal Coloboma | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Brenner Tumor | Granular Corneal Dystrophy Type 1 | Angiosarcoma | Keratitis-ichthyosis-deafness Syndrome | Spinocerebellar Ataxia | Sialoadenitis | Polyarteritis Nodosa | Autosomal Recessive Bestrophinopathy | GLUT1 Deficiency Syndrome | Hydrocephalus, Normal Pressure | Duane Retraction Syndrome | Autoimmune Autonomic Ganglionopathy | Greenberg Dysplasia | Crigler-Najjar Syndrome | Abetalipoproteinemia | IgA Nephropathy | Sleep Apnea, Obstructive | Lattice Corneal Dystrophy | Keratocystic Odontogenic Tumor | Vasculitis | Metatropic Dysplasia | Trichorhinophalangeal Syndrome | Fucosidosis | Actinomycetoma | Cocaine-Related Disorders | Ligneous Conjunctivitis | Gastritis | Craniosynostosis | Spinal Muscular Atrophy Type 2 | Binge Eating Disorder | Keratoacanthoma | Cerebrovascular Disorders | Acquired Partial Lipodystrophy | Porphyria, Acute Intermittent | Gardner Syndrome | Aldosterone Synthase Deficiency | Lennox-Gastaut Syndrome | Pathological Gambling | Osteomalacia | Muir-Torre Syndrome | Hemangioblastoma | DiGeorge Syndrome | Hyperparathyroidism, Secondary | Distal Myopathy 2 | Raynaud Phenomenon | Overactive Bladder | Apparent Mineralocorticoid Excess Syndrome | Clouston Hidrotic Ectodermal Dysplasia | Carcinoma, Squamous Cell | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Esthesioneuroblastoma | Dystonia-parkinsonism, X-linked | Myotonic Disorders | Basal Ganglia Disease | Familial Partial Lipodystrophy | Gaucher Disease | Exfoliative Dermatitis | Glycogen Storage Disease Type 5 | Asphyxia Neonatorum | Carey-Fineman-Ziter Syndrome | Fatty Aldehyde Dehydrogenase Deficiency | Encephalitis | Congenital Fiber-type Disproportion Myopathy | Torticollis | Hyperkeratosis | Galloway-Mowat Syndrome | Nemaline Myopathy 10 | Vascular Calcification | Dystonia Musculorum Deformans | Angioedema, Acquired | Choroiditis | Myofibrillar Myopathy | Kawasaki Disease | Transcobalamin Deficiency | Charcot-Marie-Tooth Disease Type 2D | Restless Legs Syndrome | Preaxial Polydactyly | Carcinoid Tumor | Dominant Optic Atrophy | Neurofibroma, Plexiform | Eosinophilic Asthma | Antley-Bixler Syndrome | Liver Failure | Takotsubo Cardiomyopathy | Chorea-acanthocytosis | Optic Neuritis | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Spondylosis | 3-methylglutaconic Aciduria | Endophthalmitis | Jaundice, Obstructive | Cancer, Brain | Pneumoconiosis | Hyperlipidemia Type V | Giant Cell Arteritis | Hepatic Veno-occlusive Disease | Hereditary Spherocytosis | Leigh Syndrome | Spina Bifida | H Syndrome | Esophageal Adenocarcinoma | Trachoma | Lymphoma, Mantle Cell | Cold-induced Sweating Syndrome | Amebiasis | Budd-Chiari Syndrome | Uremic Pruritus | Tardive Dyskinesia | Allergic Contact Dermatitis | Low Phospholipid Associated Cholelithiasis | Achondrogenesis | Schwannomatosis | Botulism | Calcium Pyrophosphate Deposition Disease | Li-Fraumeni Syndrome | Spinocerebellar Ataxia Type 15 | Papillorenal Syndrome | Occipital Neuralgia | Distal Myopathy | Thyroiditis | Myoclonic Epilepsy With Ragged Red Fibers | IMAGe Syndrome | Blue Rubber Bleb Nevus Syndrome | Jawad Syndrome | Asperger Syndrome | Keratoconus | Familial Hypertrophic Cardiomyopathy | Desmosterolosis | Hyperinsulinemic Hypoglycemia | Atrial Septal Defect | Vitiligo | Glutathione Synthetase Deficiency | Cheilitis | Tuberculosis | 3C Syndrome | Heimler Syndrome | Medulloblastoma | Trimethylaminuria | Acute Coronary Syndrome | Meier-Gorlin Syndrome | Familial Pheochromocytoma-paraganglioma | Endometritis | Epidermolysis Bullosa | Stevens-Johnson Syndrome | Polymyositis | Infertility, Male | Scleritis | Hyperhomocysteinemia | Lipid Storage Diseases | Chondromyxoid Fibroma | Urticaria | Mannosidase Deficiency Diseases | Autosomal Recessive Spastic Paraplegia Type 54 | Adenosine Deaminase 2 Deficiency | Isobutyryl-CoA Dehydrogenase Deficiency | Nance-Horan Syndrome | Knobloch Syndrome | Ichthyosis Hystrix, Curth-Macklin Type | Anti-NMDA Receptor Encephalitis | Gestational Trophoblastic Disease | Osmotic Demyelination Syndrome | CREST Syndrome | Tyrosine Hydroxylase Deficiency | Renpenning Syndrome | Pregnancy, Ectopic | Porphyria Cutanea Tarda | Sialidosis Type I | Congenital Hemolytic Anemia | Hepatitis A | Myositis, Focal | Smith-Magenis Syndrome | Donnai-Barrow Syndrome | Asthma, Nocturnal | Lymphoproliferative Disorders | Temporal Lobe Epilepsy | Parkinson Disease 6, Autosomal Recessive Early-onset | Intestinal Pseudo-obstruction | Costello Syndrome | Guillain-Barre Syndrome | Chordoma | Porphyria, Variegate | Sleep Apnea, Central | Glycogen Storage Disease Type 1b | Chronic Kidney Disease | Crouzon Syndrome With Acanthosis Nigricans | Osteogenesis Imperfecta Type II | Hypokalemic Periodic Paralysis | Kaposi Sarcoma | Hypertensive Retinopathy | Orthostatic Intolerance | Hereditary Neuropathy With Liability To Pressure Palsies | Retinal Degeneration | Hypertension, Pulmonary | Fanconi Anemia | Polydactyly | Cranial Nerve Disease | Dementia | COACH Syndrome | Joubert Syndrome | Cutaneous T-cell Lymphoma | Hyperinsulinism-hyperammonemia Syndrome | Mucormycosis | Hamartoma | Hereditary Xerocytosis | Leukocyte Adhesion Deficiency | Diabetes Type 1 | Adenosine Deaminase Deficiency | Bronchitis, Chronic | Neurofibromatosis-Noonan Syndrome | Anal Fissure | Bronchiectasis | Schizoaffective Disorder | Birt-Hogg-Dube Syndrome | Sporadic Hemiplegic Migraine | Schistosomiasis Mansoni | Generalized Epilepsy And Paroxysmal Dyskinesia | Glutaric Aciduria Type 3 | Cryptococcal Meningitis | DOCK8 Immunodeficiency Syndrome | Polymicrogyria | Borderline Personality Disorder | Creatine Deficiency Syndrome | Spinocerebellar Ataxia Type 38 | Cornelia De Lange Syndrome | Sporadic Inclusion Body Myositis | Opisthorchiasis | Craniolenticulosutural Dysplasia | Pontocerebellar Hypoplasia Type 2 | Proximal Symphalangism | Glomerulonephritis, Membranoproliferative | Carbamoyl Phosphate Synthetase I Deficiency | Premature Ejaculation | Mountain Sickness | Chiari Malformation Type I | Agammaglobulinemia | Prolymphocytic Leukemia | HUPRA Syndrome | Ganglioglioma | Cysticercosis | Chronic Inflammatory Demyelinating Polyneuropathy | Neuroblastoma | Nijmegen Breakage Syndrome | Periodontitis | Prolactinoma | Double Outlet Right Ventricle | Hemolytic Uremic Syndrome | Neuroectodermal Tumors, Primitive | Niemann-Pick Disease | Cystitis, Interstitial | Atrioventricular Septal Defect | Oligoasthenoteratozoospermia | Osteosclerosis | Anosmia, Congenital | Reye Syndrome | Amblyopia | Tuberculous Meningitis | T-cell Prolymphocytic Leukemia | Charcot-Marie-Tooth Disease Axonal Type 2N | Leprosy | Cryptorchidism | Schistosomiasis | Coffin-Lowry Syndrome | Vitamin K Deficiency | Tinea Versicolor | Asthma | Microcephaly | Autoimmune Disease | Osteoglophonic Dysplasia | Corneal Neovascularization | Open-angle Glaucoma | Agranulocytosis | Sitosterolemia | Endometrial Hyperplasia | Patent Ductus Arteriosus | Scapuloperoneal Myopathy, X-linked Dominant | Zimmermann-Laband Syndrome | CHOPS Syndrome | Hemimegalencephaly | Demyelinating Diseases | Epidermolysis Bullosa Acquisita | Periventricular Leukomalacia | Heart Block | Vitamin A Deficiency | Primary Carnitine Deficiency | Anthrax | Necrotizing Autoimmune Myopathy | Ectrodactyly | Focal Segmental Glomerulosclerosis | Juvenile Polyposis | Eosinophilia | Polymyalgia Rheumatica | Albinism | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Fahr Disease | Loeys-Dietz Syndrome Type 4 | Alopecia | Corneal Dystrophy And Perceptive Deafness | Presbyopia | Hyperbilirubinemia | Autonomic Nervous System Disorders | Hyperacusis | Isovaleric Acidemia | Thanatophoric Dysplasia | Cryptosporidiosis | Diabetes Mellitus, Transient Neonatal | Acute Lymphocytic Leukemia | Mucolipidosis Type IV | Mosaic Variegated Aneuploidy Syndrome 2 | Papulopustular Rosacea | Noonan Syndrome | Cholestasis | Benign Familial Infantile Seizures | Skin Carcinoma | Chudley-McCullough Syndrome | Mumps | Cerebellar Ataxia, Cayman Type | Alagille Syndrome | Bloom Syndrome | Autoimmune Polyendocrinopathy Syndrome Type I | Paraganglioma | Endocarditis | Epidermolysis Bullosa Simplex | Vitreoretinopathy, Proliferative | Rhizomelic Chondrodysplasia Punctata | Low Tension Glaucoma | Tic Disorder | Microvillus Inclusion Disease | Non-Hodgkin Lymphoma | Autosomal Recessive Spastic Paraplegia Type 75 | Gigantism | Schuurs-Hoeijmakers Syndrome | Congenital Disorders Of Glycosylation | Myoclonic Atonic Epilepsy | Spondylometaphyseal Dysplasia | Takayasu's Arteritis | Schwannoma | Scabies | Alopecia Totalis | Hepatitis | Pulmonary Veno-occlusive Disease | Choroideremia | Stroke, Hemorrhagic | Parvovirus B19 Infection | Roberts Syndrome | Schizencephaly | Branchiootorenal Syndrome | Glycogen Storage Disease Type 0 | Asthma, Exercise-induced | Seizures | Cataract | Combined Pituitary Hormone Deficiency | Silver-Russell Syndrome | Hypoplastic Left Heart Syndrome | Paroxysmal Kinesigenic Dyskinesia | Spastic Paraplegia Type 7