Disease

Chorea-acanthocytosis

About the Disease
Choreoacanthocytosis, also known as chorea-acanthocytosis, is related to lingual-facial-buccal dyskinesia and oromandibular dystonia, and has symptoms including seizures, personality changes and recurrent muscle twitches (symptom). An important gene associated with Choreoacanthocytosis is VPS13A (Vacuolar Protein Sorting 13 Homolog A), and among its related pathways/superpathways is superpathway of coenzyme A biosynthesis III (mammals). Affiliated tissues include tongue, skin and brain, and related phenotypes are chorea and myopathy

Common Targets
VPS13A

疾病靶点研报
Chorea-acanthocytosis

Note: If you'd like to get a target analysis report for Chorea-acanthocytosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Chorea-acanthocytosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Sarcoidosis, Pulmonary | Osteogenesis Imperfecta Type V | Papilledema | Hypocalcemia | Leukemia-lymphoma, Adult T-cell | Familial Exudative Vitreoretinopathy | Alazami Syndrome | Subcortical Band Heterotopia | Trichomegaly | Heart Failure | Roberts Syndrome | Cranioectodermal Dysplasia | Snyder-Robinson Syndrome | Erythromelalgia | Alzheimer Disease, Late Onset | Pure Red Cell Aplasia | Malonyl-CoA Decarboxylase Deficiency | Postaxial Polydactyly | Schizophrenia, Paranoid | Cancer, Kidney | Cystinuria | Adult Polyglucosan Body Disease | Lymphoma, Follicular | Paronychia | Herpes Simplex Dermatitis | Charcot-Marie-Tooth Disease, Type 2 | Hypoglycemia | Supravalvular Aortic Stenosis | Sweet Syndrome | Keratitis | Muir-Torre Syndrome | Pyruvate Kinase Deficiency | Crohn's Disease | Stevens-Johnson Syndrome | Acute Coronary Syndrome | Retinal Degeneration | Orthostatic Intolerance | Nemaline Myopathy 8 | Cancer, Brain | Hypotension, Orthostatic | Conduct Disorder | Bethlem Myopathy | Spondylolisthesis | Episodic Ataxia Type 2 | Vitiligo | Myoclonic Epilepsy With Ragged Red Fibers | Pulmonary Stenosis | Pain | Chondrodysplasia Punctata 2, X-linked Dominant | Down Syndrome | ACTH-independent Macronodular Adrenal Hyperplasia | GLUT1 Deficiency Syndrome | Thyroiditis, Autoimmune | Pheochromocytoma | Retinal Telangiectasia | Oculopharyngeal Muscular Dystrophy | Multiple Sclerosis, Chronic Progressive | Cyst | Congenital Central Hypoventilation Syndrome | Fontaine Progeroid Syndrome | Neuroma | DNA Ligase IV Deficiency | Hypervalinemia | Chorea | Autism Spectrum Disorders | Hemangioblastoma | Weill-Marchesani Syndrome | Intracerebral Hemorrhage | Iron Deficiency Anemia | Gaucher Disease | Adenomyosis | Congenital Absence Of Vas Deferens | Inflammatory Linear Verrucous Epidermal Nevus | Mucormycosis | Adenomatoid Tumor | Dysmorphophobia | AIDS | Distal Myopathy 2 | Pyruvate Carboxylase Deficiency Disease | Schizotypal Personality Disorder | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Neurodermatitis | Glycogen Storage Disease Type 1b | Aneurysm, Abdominal Aortic | Congenital Hemolytic Anemia | Cryopyrin-associated Periodic Syndromes | Retinopathy Of Prematurity | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Miyoshi Myopathy | Generalized Epilepsy With Febrile Seizures Plus | Meesmann Corneal Dystrophy | Batten Disease | Neurofibromatosis | Spinocerebellar Ataxia Type 13 | Pilomatrix Carcinoma | Paternal Uniparental Disomy Of Chromosome 14 | Congenital Heart Block | Diarrhea | Congenital Aniridia | Transient Bullous Dermolysis Of The Newborn | Tyrosine Hydroxylase Deficiency | Jawad Syndrome | Scabies | Larsen Syndrome | Guillain-Barre Syndrome | X-linked Creatine Transporter Deficiency | Apparent Mineralocorticoid Excess Syndrome | Emery-Dreifuss Muscular Dystrophy | Cat Eye Syndrome | Superficial Spreading Melanoma | Scapuloperoneal Spinal Muscular Atrophy | Borderline Personality Disorder | Glomerulonephritis, Membranoproliferative | Carcinoma In Situ | Hyperferritinemia-cataract Syndrome | Optic Nerve Hypoplasia, Bilateral | Postpartum Depression | Cancer, Colon | Cole-Carpenter Syndrome | Perry Syndrome | Hepatitis E | Seasonal Mood Disorder | Metanephric Adenoma | Angina Pectoris | Hyperoxaluria | Aldosterone Deficiency | CDKL5 Deficiency Disorder | Parkinson Disease 6, Autosomal Recessive Early-onset | Hypersensitivity Pneumonitis | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Myelomeningocele | Gastritis | Hepatorenal Syndrome | Periventricular Nodular Heterotopia | Myoclonic Atonic Epilepsy | T-cell Leukemia | Eosinophilic Asthma | Atrial Septal Defect | Hypertension, Portal | Gilbert Syndrome | T-cell Prolymphocytic Leukemia | X-linked Acrogigantism | Eczema | GATA2 Deficiency | Anodontia | Congenital Dyserythropoietic Anemia Type 4 | Congenital Disorders Of Glycosylation Type II | Spinocerebellar Ataxia Type 10 | Nephronophthisis | Disseminated Superficial Actinic Porokeratosis | Tremor | Mucolipidosis Type II | Lymphomatoid Granulomatosis | Chromosome 17q21.31 Deletion Syndrome | Familial Digital Arthropathy-brachydactyly | Hyperinsulinemia | Waardenburg Syndrome Type 1 | Actinomycetoma | Acromicric Dysplasia | Congenital Generalized Lipodystrophy | Hyperostosis | Guttate Psoriasis | Schuurs-Hoeijmakers Syndrome | Spinocerebellar Ataxia Type 3 | Fucosidosis | Lipoma | CEDNIK Syndrome | Wilson's Disease | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Hepatitis, Autoimmune | Micro Syndrome | Hereditary Xerocytosis | Perivascular Epithelioid Cell Tumor | Narcolepsy | Pathological Gambling | Multisystemic Smooth Muscle Dysfunction Syndrome | Nijmegen Breakage Syndrome | Hyperbilirubinemia | Specific Granule Deficiency | Recurrent Respiratory Papillomatosis | Premature Ejaculation | Coronary Artery Disease | Meningococcal Meningitis | Epidermolysis Bullosa Acquisita | Benign Recurrent Intrahepatic Cholestasis 1 | Globozoospermia | Familial Pheochromocytoma-paraganglioma | Familial Episodic Pain Syndrome | Hypereosinophilic Syndrome | Atopy | Lichen Planus | Myoclonus-dystonia Syndrome | Barrett Esophagus | Neurofibromatosis-Noonan Syndrome | Sleep Disorder | Trichuriasis | Aplasia Cutis Congenita | Glycogen Storage Disease Type 1a | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Trigonocephaly | 3C Syndrome | Hypercalciuria | Alcoholism | Odonto-onycho-dermal Dysplasia | Allan-Herndon-Dudley Syndrome | Axenfeld-Rieger Syndrome | Familial Glucocorticoid Deficiency | Spondylocostal Dysostosis | Primrose Syndrome | Occipital Neuralgia | Joubert Syndrome 2 | Chronic Lymphocytic Leukemia | Mixed Connective Tissue Disease | Myelitis, Transverse | Hypertension | Follicular Dendritic Cell Sarcoma | Light Chain Amyloidosis | Rhabdomyosarcoma, Embryonal | Behavioral Variant Of Frontotemporal Dementia | Idiopathic Pulmonary Fibrosis | Thalassemia | Stroke, Hemorrhagic | Charcot-Marie-Tooth Disease, Type 6 | Optic Atrophy 2 | Lupus Erythematosus | Diabetic Nephropathy | 3-methylcrotonyl-CoA Carboxylase Deficiency | Delirium | Myhre Syndrome | Tetanus | Gout | Glutaric Aciduria Type 2 | Hyperhomocysteinemia | Rhizomelic Chondrodysplasia Punctata | Canavan Disease | Hypertensive Retinopathy | Bullous Pemphigoid | Meniere's Disease | Porphyria Cutanea Tarda | Azoospermia | Hereditary Neuropathy With Liability To Pressure Palsies | Graves Disease | Cocaine-Related Disorders | Lung Diseases | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Sjogren Syndrome | Eating Disorder | Cockayne Syndrome | Fahr Disease | Spina Bifida | Pseudohypoparathyroidism Type 2 | Sickle Cell Disease | Hyperkeratosis | X-linked Myotubular Myopathy | Gigantism | Tetraplegia | Amblyopia | Primary Torsion Dystonia | Cholesteryl Ester Storage Disease | Renal Medullary Carcinoma | Cholestasis | Osteomyelitis | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Varices | Purpura, Thrombotic Thrombocytopenic | Paroxysmal Nocturnal Hemoglobinuria | Nutrition Disorders | Polycythemia | Gastric Atrophy | KBG Syndrome | Prader-Willi Syndrome | Peters-plus Syndrome | VACTERL/VATER Association | Multiple Hamartoma Syndrome | Congenital Primary Aphakia | D-2-Hydroxyglutaric Aciduria | Waardenburg Syndrome Type 2A | Eosinophilia | Myoclonus | Cerebellofaciodental Syndrome | Primary Hyperoxaluria Type 3 | Cardiac Arrest | IgA Deficiency | 5-oxoprolinase Deficiency | Ornithine Transcarbamylase Deficiency | Hyperphenylalaninemia | Carcinoma, Merkel Cell | Split Hand-foot Malformation | Hypoalbuminemia | Vasculitis | Amelogenesis Imperfecta | Lafora Disease | Diabetes Mellitus, Transient Neonatal | Nestor-Guillermo Progeria Syndrome | Multiple Sclerosis, Relapsing-remitting | Cellulitis | LMNA-related Congenital Muscular Dystrophy | Charcot-Marie-Tooth Disease, Type 2A | Adenosine Deaminase 2 Deficiency | Thymoma, Malignant | Calcium Pyrophosphate Deposition Disease | Lentigo | Osteosarcoma | Congenital Hypofibrinogenemia | Blepharo-cheilo-odontic Syndrome | Keratoconjunctivitis | X-linked Charcot-Marie-Tooth Disease | Glaucomatocyclitic Crisis | Hydrocephalus | Celiac Disease | Meleda Disease | Eclampsia | Hemoglobinopathies | Hyperthermia, Malignant | Empyema | Polycystic Ovary Syndrome | Myasthenia | Antley-Bixler Syndrome | Infertility, Male | Sotos Syndrome | Diabetes Type 2 | Adenoma, Villous | Distal Myopathy | Pyruvate Dehydrogenase Deficiency | Barakat Syndrome | Urofacial Syndrome | Hypotrichosis Simplex | Marinesco-Sjogren Syndrome | Jalili Syndrome | Pterygium | Cerebellar Ataxia, Cayman Type | Dementia | Oligoastrocytoma | Klippel-Feil Syndrome | Gastroschisis | Chromosome 9q34.3 Deletion Syndrome | Polydactyly | Usher Syndrome Type III | Monilethrix | Niemann-Pick Disease, Type A | Allergic Contact Dermatitis | Porphyria | Prolidase Deficiency | Primary Progressive Aphasia | Coffin-Lowry Syndrome | Papillorenal Syndrome | Syphilis | Acute Myeloid Leukemia | Pulverulent Zonular Cataract | Adrenomyeloneuropathy | Wolff-Parkinson-White Syndrome | Spinal Muscular Atrophy Type 2 | Spondyloepiphyseal Dysplasia Tarda, X-linked | Auriculocondylar Syndrome | Pseudomyxoma Peritonei | Cardiospondylocarpofacial Syndrome | Malaria | Bacterial Meningitis | Hypotrichosis | Sialidosis | Charcot-Marie-Tooth Disease Type 2D | Optic Neuritis | Muscle Wasting | CREST Syndrome | Pleural Tuberculosis | Cousin Syndrome | Mosaic Variegated Aneuploidy Syndrome 2 | Glaucoma, Congenital | Hepatitis | Pycnodysostosis | Goiter | Extramammary Paget's Disease | Cannabis Abuse | Scleroderma, Diffuse | Polyarteritis Nodosa | Dysgerminoma | Megalencephaly | Carcinoma, Transitional Cell | Mitochondrial Encephalomyopathy | Hidradenitis | Ameloblastic Carcinoma | Methemoglobinemia | Ependymoma | Liebenberg Syndrome | Micropenis | Basan Syndrome | Angelman Syndrome | Kashin-Beck Disease | Uveitis | Encephalopathy | Hypersomnia | Pemphigoid | Sporadic Hemiplegic Migraine | Chanarin-Dorfman Syndrome | Epiphyseal Chondrodysplasia, Miura Type | 3-hydroxy-3-methylglutaric Aciduria | Sick Sinus Syndrome | Pelizaeus-Merzbacher Disease | Porokeratosis | Oculocutaneous Albinism Type 2