Acute Lung Injury

About the Disease
Adult Respiratory Distress Syndrome, also known as acute respiratory distress syndrome, is related to critical covid-19 and pulmonary edema, and has symptoms including apnea, cheyne-stokes respiration and coughing. An important gene associated with Adult Respiratory Distress Syndrome is CXCL8 (C-X-C Motif Chemokine Ligand 8), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Iron and Ibuprofen have been mentioned in the context of this disorder. Affiliated tissues include Lung, and related phenotypes are respiratory failure and tachypnea

Common Targets
SLC27A2 | Heat shock protein 90 (nonspecified subtype) | Integrin alpha4beta1 (VLA-4) receptor | H4C16 | MYD88 | PF4 | TYK2 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | Protein Kinase B (PKB/Akt) (nonspecified subtype) | IKBKB | CYSLTR1 | PDGFRB | P2RX1 | DIO2 | NEU1 | Nuclear factor of activated T-cells (nonspecified subtype) | Chemokine CXC receptor (nonspecified subtype) | G1950 | G1432 | PPARG | PRKCA | TRPV4 | SUFU | MAP3K5 | NR3C1 | KEAP1 | ICAM1 | HMGCR | BCR | SFTPB | Chymotrypsin (nonspecified subtype) | G9429 | PDE10A | Histone H3 (nonspecified subtype) | CD14 | FPR1 | F3 | DCUN1D1 | SCARB1 | G5743 | alpha-Adrenoceptor (nonspecified subtype) | KCNK2 | EIF2AK2 | Neurotrophic Factor (nonspecified subtype) | CCR2 | Tubulin | CIRBP | FGFR1 | SLC22A6 | TRAF6 | F2 | ANGPT2 | G3630 | PGAM5-KEAP1-NRF2 Complex | SERPINC1 | ACKR1 | VDR | TAS2R46 | SELP | G3480 | Adenylate Cyclase (nonspecified subtype) | IRAK4 | FBXO3 | NR1H4 | GADD45A | IL10 | Epithelial Sodium Channel (ENaC) | SLC22A8 | G4193 | TRPC6 | PYCARD | PTGDR2 | Interferon alpha/beta Receptor (nonspecified subtype) | PTP4A3 | PRTN3 | IL1B | CALCA | Trypsin (nonspecified subtype) | G7422 | G3569 | MBL2 | Elastase (nonspecified subtype) | Serine protease (nonspecified subtype) | Caspase (nonspecified subtype) | NOS2 | NMDA receptor | PDE2A | PDGFRA | CCR1 | CFTR | NOX3 | FPR2 | JAK2 | UBE2M | Complement Complex | CCR5 | VHL | BDKRB1 | DCLK1 | JAK3 | NAMPT | G3082 | FAS | JAK1 | NF-kappaB (NFkB) | MIF | G3576 | MIR92A1 | STING1 | ALOX5 | NADPH Oxidase Complex | G3146 | Nitric oxide synthase (NOS) (nonspecified subtype) | FBXO48 | MIR92A2 | IRAK1 | TNFRSF1A | KIT | ABL1 | alpha-Amylase (nonspecified subtype) | TGFB1 | G7124 | NADPH Oxidase (nonspecified subtype) | SLC26A4 | Integrin alphavbeta8 Receptor | SERPING1 | LTA4H | POLR2E | GRIN2B | G7099 | PRDX6 | PI3 | MPO | RHOA | THBD | GPR182 | ARF6 | LY96 | HIF1A | TLR4/MD-2 complex | AMP-activated protein kinase (AMPK) | MDM4 | SELE | PPIA | Protein Phosphatase 2B | Monoamine oxidase (MAO) (nonspecified subtype) | CGAS | Phosphodiesterase IV (PDE4) (nonspecified subtype) | CSF1R | GYPA | BDKRB2 | ELANE | G4780

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