Endometriosis

About the Disease
Endometriosis, also known as endometriosis, site unspecified, is related to endometriosis of ovary and endometrial adenocarcinoma, and has symptoms including pelvic pain and pain and other symptoms associated with female genital organs. An important gene associated with Endometriosis is ENDO1 (Endometriosis, Susceptibility To, 1), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index. The drugs Dienogest and Progesterone have been mentioned in the context of this disorder. Affiliated tissues include uterus, ovary and skin.

Common Targets
RNLS | KRTAP5-5 | FCGR2B | SLX4 | MIR503 | CDH13 | MYO5C | RECQL4 | IL12B | ZBTB10 | UBB | BABAM1 | DDC | FAP | HDAC6 | MIR4429 | AAAS | MRPL15 | G3620 | ZFPM1 | MUC17 | BTK | IL33 | MICAL2 | MALT1 | G2335 | POLD2 | MIR100 | THBS1 | FOXR1 | NTMT2 | PKP3 | CREM | MAMDC4 | HIF1A | HIF1A-AS3 | BDNF | LOC100506236 | PTGES | WNT7A | ADAMTS7 | NF-kappaB (NFkB) | TAS2R8 | HSD17B2 | Interleukin 17 (nonspecified subtype) | AKAP9 | GPR35 | IL1RN | ITIH2 | ZFP69B | PREP | CDK6 | LINC00339 | ZNF385D | LINC00824 | CSF1R | CCDC6 | EPS8L3 | KISS1 | GPRIN2 | MIR451A | KRTAP5-2 | THSD4 | PMP22 | AXL | RRAGA | IGSF3 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | SCAF8 | PAH | G5728 | OR2T33 | CYP2D6 | CSKMT | CCR6 | WDR86 | RBMXL3 | NR3C2 | GATA4 | ITGA10 | DDX51 | BAZ2A | KMT2C | CYP2C19 | SNCG | MYO9A | GREB1 | MAGEC1 | G7099 | HOXA9 | NR1H2 | Interleukin-1 (nonspecified subtype) | SSU72 | DNAI7 | DNAH3 | RLIM | NAT2 | DPYSL2 | UBXN11 | BRCA2 | ACE | ID2 | TAF1L | CSPG4 | SF3B4 | CEP250 | SLC25A37 | ALPP | G1029 | GCNA | USP20 | PTH2R | MGAT3 | CAB39L | FSHR | LCK | UBR4 | NECAB1 | CYP17A1 | IL10RA | TYK2 | ERBB3 | IRS2 | PGM2L1 | PDGFRB | IL4R | TTC39B | PMS2 | NR1H3 | BMP3 | DGAT2 | WASHC2C | ANKRD16 | DLG5 | HOXA10 | TNFRSF18 | TYR | CNTNAP3 | CHD5 | PAPPA2 | SMOC1 | CYP1A1 | RANBP6 | GSTA1 | COL4A1 | ERICH1 | KRTAP5-1 | DFFA | DRD2 | OR6K2 | F11-AS1 | CFAP54 | KRTAP5-3 | ESR2 | CCDC169 | PPIP5K2 | FRY | LOC105377795 | CHIT1 | TP73 | GATA6 | STAB2 | MEX3A | ZNF804B | CASR | DLGAP3 | COMT | XIAP | PRDM14 | NID1 | ENG | USP24 | MKNK1 | ICAM1 | CD44 | CHFR | SMC2 | P2RX3 | PGR | TIPARP | EEFSEC | NUTM2F | IQGAP3 | Estrogen receptor (nonspecified subtype) | NUP42 | G7157 | SYTL1 | HOXA11 | FAM47C | G23411 | WAC | NAT1 | MAP3K14 | NR4A1 | E2F2 | CDKN2B-AS1 | IGFN1 | FLRT2 | KLLN | RCOR2 | TNFAIP2 | MTRR | MIR100HG | HAGLROS | EDDM3A | USP17L2 | FLT4 | PHLDB1 | KDM3B | RSC1A1 | FGD6 | Oxysterols receptor LXR (nonspecified subtype) | CCDC183 | LNC-LBCS | KDM4E | TSC2 | EPPK1 | SOD2 | NTRK3 | NR5A1 | PPARG | ATAD3A | PUM1 | HLA-DQA2 | PTCH1 | Reverse transcriptase (Telomerase) | TBX3 | G5595 | NEK7 | KLK3 | MIR423 | PMEL | SCRIB | DEPP1 | IRAG2 | PRSS3 | HSD11B1 | OR8B3 | PRAMEF1 | IFNLR1 | GATA2 | CRYBG2 | CACNA2D4 | SART3 | G999 | STK11 | TAF12 | MIR26A1 | FLT1 | ZNF681 | FCRL3 | IL12RB2 | CCDC82 | PRRC2B | ASH2L | Prolactin receptor (isoform 1) | IL27 | ACSM5 | RBM12B | PPP1R3A | STAT5 (nonspecified subtype) | WNK2 | NTRK1 | PHF2 | CYP2W1 | VEZT | ARAP1 | IRAK4 | GSTT1 | SIDT2 | SMARCD1 | PAX5 | G3480 | G2099 | CELSR2 | MUC5B | ASPSCR1 | OXT | OR52B4 | PIKFYVE | MMP7 | F2 | PCF11 | PYCARD | FAM98B | R3HCC1L | AHNAK | UGT2B28 | ZCWPW1 | RADIL | NFE2L3 | LINC00703 | MUC12 | MERTK | BIRC3 | PRL | UBQLN4 | SKAP1 | SLC2A7 | RIN3 | PDE4DIP | FLG2 | PKD1L1 | FGB | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | AGAP1 | SF1 | GATA5 | HOXA2 | STIL | OR4F6 | ANKLE1 | PADI3 | ACVRL1 | PTGER4 | Mitogen-Activated Protein Kinase (nonspecified subtype) | MRPS16 | MTSS1 | G4318 | ESRRA | SPATA31D3 | LRP1 | PRG4 | GPIHBP1 | EPX | RARB | LAS1L | RPL35 | CT47B1 | RTN4RL1 | MIR27A | MIR196B | NFIL3 | ZFPM2 | NR3C1 | STS | G7124 | AKR1C3 | GNRHR | G4193 | FAM234A | LRRC47 | RB1 | ASTN1 | CTLA4 | G2064 | PDZD7 | PIK3CA | TRIM64B | ZNF423 | KIAA2013 | CPQ | 17-beta-Hydroxysteroid dehydrogenase (nonspecified subtype) | RXRA | PKM | CCR1 | TYRO3 | FASN | GAK | TMCO3 | SFRP5 | FLT3 | ATN1 | AP-1 Transcription Factor Complex | G367 | REM2 | UBXN1 | IL1A | IL2 | LIF | CDCA2 | WWC3 | TAL1 | TDO2 | CCDC22 | KCNQ1 | DPP6 | G5243 | SRRM4 | C2CD3 | NAT10 | Poly [ADP-ribose] polymerase (nonspecified subtype) | G196 | MMP2 | CDKN1B | TCHH | ERBB4 | GRAMD1B | BDKRB1 | IL16 | WT1 | ARMCX4 | CA9 | ERO1B | TSPYL2 | PAX6 | FCGR2A | SLC2A1 | SPHK1 | SNAPC1 | CHMP4C | IL10 | G672 | SNAPC3 | RERG | MGMT | ETV3L | AHNAK2 | TALDO1 | SETX | SLC5A1 | KDR | MTHFR | METAP2 | ELFN1 | MIR146A | KRT74 | EML5 | CAPN5 | PGF | MGAM | SLC10A2 | G1956 | OR2D3 | RPS2P32 | PLA2G2D | PAGE1 | IFNG | RAB40A | SYNE1 | GAA | OR2D2 | ARL14EP-DT | KMT2D | OR6C2 | SDK1 | WHRN | CFAP251 | CADM1 | HSD17B1 | KCNU1 | VHL | MYEF2 | CFTR | MFSD13A | PRB4 | GSTM1 | AGER | ZNF735 | Proteasome Complex | KCNA1 | SOAT2 | DNM3 | CYP1B1 | G7422 | ARID1A | ALKBH8 | NID2 | HEY2 | GSTP1 | MTIF3 | MINDY4 | ZNF721 | ZNF180 | ASTN2 | G3845 | SYCE1 | OR51Q1 | APC | HSD3B1 | USP7 | FSCB | MIR196A2 | PXDNL | CYP19A1 | VSIG2 | HOXA3 | MTR | MIR6074 | CFAP126 | LOC105376845 | AK9 | DIABLO | ENOX2 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | G472 | TBK1 | LOC105376850 | CCDC168 | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | UNC5D | TFR2 | FGF2 | CRBN | ZNF16 | ATP2B4 | NFASC | MLLT10 | CTNNB1 | MSH6 | LOC105370134 | MAOB | OXTR | HOTAIR | UNC93A | IKBKE | KLF8 | MUC6 | IL13 | G7015 | BMPR1B | OR5W2 | SIK3 | MIR499A | HNF1B | PTGER2 | FOXP3 | Interleukin 23 complex (IL-23) | IL1B | ATXN1L | G3576 | COQ4 | HELB | ADGRA2 | AEN | RAPSN | G3569 | G6714 | MATN2 | PRR25 | KISS1R | NEBL | HOXA5 | KLHL6 | GPRC5A | INPP5E | HSD17B3 | HLA-DQB1 | DNAH10 | NTRK2 | WNT4 | ZNF678 | CNGA2 | MLST8 | BIRC2 | SCGB1D1 | SELE | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | HHIPL2 | BEGAIN | MDM4 | MST1R | NACAD | DCAF5 | VWA8 | MTMR7 | Uncharacterized LOC102723888, transcript variant X1 | ADAMTSL2 | TMEM200B | ENPP2 | ODF1

Note: If you'd like to get a target analysis report for Endometriosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Endometriosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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