Polycystic Liver

About the Disease
Polycystic Liver Disease, also known as autosomal dominant polycystic liver disease, is related to polycystic liver disease 1 with or without kidney cysts and polycystic kidney disease 3 with or without polycystic liver disease, and has symptoms including hepatosplenomegaly An important gene associated with Polycystic Liver Disease is PRKCSH (Protein Kinase C Substrate 80K-H), and among its related pathways/superpathways are WNT Signaling and Bardet-Biedl syndrome. The drugs Miconazole and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include liver, kidney and pancreas, and related phenotypes are hepatomegaly and abdominal distention

Common Targets
FKBP1A | PKD1 | GH1 | Somatostatin receptor (nonspecified subtype) | CDK5/p25 | CDK5 | LRP5 | SSTR3 | PKHD1 | BUB1 | FASN | SST | UGT1A1 | PKM | GANAB | SSTR5 | SSTR1 | AMP-activated protein kinase (AMPK) | ALG8 | HDAC6 | G2475 | PRKCSH | SEC61A1 | GPBAR1 | SSTR2 | G5243

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