Polycystic Ovary Syndrome

About the Disease
Polycystic Ovary Syndrome, also known as polycystic ovarian syndrome, is related to prediabetes syndrome and alopecia, androgenetic, 1, and has symptoms including pelvic pain An important gene associated with Polycystic Ovary Syndrome is PCOS1 (Polycystic Ovary Syndrome 1), and among its related pathways/superpathways are Metabolism of steroids and Glucose / Energy Metabolism. The drugs Iron and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include ovary, liver and skin, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Common Targets
G7295 | PGR | G367 | ERBB3 | NRIP1 | DNA Topoisomerase II (nonspecified subtype) | ZBTB16 | TOX3 | FFAR1 | TENM2 | CYP17A1 | GHRL | ADIPOQ | SEC16B | SMG6 | XDH | G3480 | CYP1A1 | G7422 | CDKN2B-AS1 | HSD11B1 | G5594 | G3479 | NF-kappaB (NFkB) | GSTT1 | AKR1C2 | PTPN1 | FAM167A-AS1 | ETV5 | FSHR | PGPEP1 | GSK3B | NLRP11 | FBN3 | SRD5A1 | MYL6B | ETS2-AS1 | CADM2 | GCK | SH2B1 | INSL3 | SOD2 | RASA2 | SERPINE1 | GHRLOS | POMC | CCDC171 | LPP | MYO10 | RABEP1 | SRD5A2 | PDE5A | INSR | HMGA2 | Mitogen-Activated Protein Kinase (nonspecified subtype) | FHIT | SUMO1P1 | NLRC3 | G5563 | RNF44 | KAT8 | TMEM150B | C11orf65 | LEP | STK11 | SUOX | PAPSS2 | IRAK4 | CYC1 | NAV1 | G5595 | FPGT-TNNI3K | HHIP | NWD1 | RARB | CYP2E1 | CYP11A1 | IRS4 | SHBG | MIR141 | FAAH | ACVR2A | ATP2A1 | VHL | GNRH1 | AKT2 | DFFB | ADRB2 | SLC22A2 | LOC105371116 | PCNX2 | EHBP1 | CRBN | HIP1 | TET1 | MATN4 | MAP4K4 | CLIP1 | PIKFYVE | AMHR2 | ZP4 | G2309 | GSTM1 | MGAT5B | MCM8 | GNRHR | ERBB4 | ACVR1 | TGFB1 | LEPR | ACER3 | KCNQ1 | TBX2 | QPCTL | PRKAG3 | KCNK3 | GPR84 | LMX1B | CYP19A1 | LHCGR | PON1 | STON1-GTF2A1L | CRHR1 | LMNA | ORC4 | AKR1C3 | LINC02210-CRHR1 | BDNF-AS | GRID1 | CCDC33 | HSD17B6 | ASB4 | H6PD | MTCH2 | Class III phosphatidylinositol 3-kinase (PI3-kinase) sub-complex | SLC5A1 | ENDOV | AGER | PIK3C3 | SCN5A | FTO | LOC102724934 | ELAVL4 | HLA-C | POC5 | MIR429 | APOA1 | MAOB | HIPK3 | SCARB2 | CHEK2 | FEM1B | INO80E | AMP-activated protein kinase (AMPK) | ACTG1 | HSD17B12 | GPX4 | HLA-DRB1 | SGTA | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | FIGN | MAPRE1 | AOPEP | TAL1 | METAP2 | G5243 | G4780 | EPHX1 | TCF7L2 | DMXL2 | MTHFR | LOC105369844 | CHRM2 | CMKLR1 | RMC1 | PIK3CA | PPARG | MPO | AMH | Mitochondrial pyruvate carrier complex (MPC) | PRKN | HLA-B | LOC107984901 | FEM1A | BDNF | LINC00907 | FABP4 | ARL14EP-DT | LOC105378797 | RAB5B | MIR126 | G7124 | ROBO1 | IGF2BP2 | ILRUN | NR3C1 | LINC01060 | IGFBPL1 | IRS1 | ZC3H4 | MTIF3 | CNR1 | GYS2 | LINC01709 | G3569 | KDM6A | CYBA | G2099 | PON2 | SLC5A2 | GPBAR1 | ALDOA | G10413 | HSD17B3 | USP37 | THADA | LOC102723403 | DLGAP2 | SLC2A8 | LOC107985979 | LOC105372666 | PTGS1 | FABP1 | DENND1A | MAOA | G3630 | TACR3 | FSHB | LOC105372667 | G9429 | AHRR | ESR2 | RPTOR | SREBF1 | AGBL4 | NRXN3 | VDR | LINGO2 | GABRB1 | GNAT2 | IL1B | SLC39A8 | NT5C2 | MAP2K1 | G23411 | RNLS | CAPN10 | SLC22A1 | G1026 | CYP2D6 | SBK1 | CMKLR2 | ZNRF3 | TOMM40 | LOC107986544 | FUBP1 | TRIM66

Note: If you'd like to get a target analysis report for Polycystic Ovary Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Polycystic Ovary Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

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