Disease

Autoimmune Hepatitis

About the Disease
Autoimmune Hepatitis, also known as hepatitis, autoimmune, is related to hepatitis and autoimmune cholangitis. An important gene associated with Autoimmune Hepatitis is SEPSECS (Sep (O-Phosphoserine) TRNA:Sec (Selenocysteine) TRNA Synthase), and among its related pathways/superpathways are NF-kappaB Signaling and CD28 co-stimulation. The drugs Azathioprine and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include Blood and Umbilical Cord, and related phenotypes are increased circulating igg level and elevated hepatic transaminase

Common Targets
FKBP1A | LTA | MLKL | PNPLA3 | HLA-A | MIF-AS1 | G3630 | PSMB9 | PPP3R2 | TPMT | TRPV2 | G7124 | PPP3CC | IL10 | Integrin alpha4beta7 (LPAM-1) receptor | IL-2 receptor | CTLA4 | TM6SF2 | STAT4 | IL2 | TRPA1 | MBOAT7 | PTPN22 | HSD17B13 | Immunoproteasome | HLA-DQB1 | MIF | TGFB1 | G7099 | G5133 | PPP3CB | HLA-C | PPP3R1 | TNFRSF13C | GPR55 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | G6774 | KRR1 | IFNL4 | RIPK1 | PSMB8 | S1PR1 | SH2B3 | HLA-DRB1 | OPRM1 | MADCAM1 | HLA-B | OPRK1 | TRPM8 | G2099 | NR3C1 | HLA-DQA1 | CX3CL1 | TRPV1 | KCNA3

疾病靶点研报
Autoimmune Hepatitis

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