Apert Syndrome

About the Disease
Apert Syndrome, also known as acrocephalosyndactyly type i, is related to hypertelorism and hydrocephalus. An important gene associated with Apert Syndrome is FGFR2 (Fibroblast Growth Factor Receptor 2), and among its related pathways/superpathways are ERK Signaling and Apoptotic Pathways in Synovial Fibroblasts. Affiliated tissues include bone, eye and brain, and related phenotypes are frontal bossing and depressed nasal bridge

Common Targets
FGFR3 | FGFR1 | PTPN11 | FGFR2

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