GM1 Gangliosidosis

About the Disease
Gm1 Gangliosidosis, also known as beta-galactosidase deficiency, is related to gm1-gangliosidosis, type i and gm1-gangliosidosis, type iii. An important gene associated with Gm1 Gangliosidosis is GLB1 (Galactosidase Beta 1), and among its related pathways/superpathways are Innate Immune System and Metabolism. The drugs Miglustat and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and brain, and related phenotypes are hyperreflexia and nystagmus

Common Targets
UGCG | INSR | Chaperone (nonspecified subtype) | GLB1 | GBA2

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