Fatty Aldehyde Dehydrogenase Deficiency

About the Disease
Sjogren-Larsson Syndrome, also known as sj枚gren-larsson syndrome, is related to quadriplegia and autosomal recessive congenital ichthyosis, and has symptoms including muscle spasticity, seizures and photophobia. An important gene associated with Sjogren-Larsson Syndrome is ALDH3A2 (Aldehyde Dehydrogenase 3 Family Member A2), and among its related pathways/superpathways are Metabolism and Sphingolipid metabolism. The drug Ethanol has been mentioned in the context of this disorder. Affiliated tissues include skin, eye and retina, and related phenotypes are intellectual disability and abnormal pyramidal sign

Common Targets
TTC21B | NPHP4 | ACADVL | ALDH3A2 | IQCB1 | SDCCAG8 | NPHP1

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