Diffuse Mesangial Sclerosis

About the Disease
Diffuse Mesangial Sclerosis, also known as familial mesangial sclerosis, is related to nephrotic syndrome, type 4 and denys-drash syndrome. An important gene associated with Diffuse Mesangial Sclerosis is WT1 (WT1 Transcription Factor), and among its related pathways/superpathways are Integrin Pathway and Phospholipase-C Pathway. Affiliated tissues include kidney, eye and thyroid, and related phenotypes are renal/urinary system and growth/size/body region

Common Targets
PDSS2

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